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The role for insulin-like growth factor-I in preimplantation embryonic development and decidualization following superovulation in the rat

https://cwslc.andornot.com/en/permalink/catalog113980

Katagiri, Seiji. [Vancouver, BC?]: University of British Columbia , 1996.

Website: http://hdl.handle.net/2429/4814

Material Type: Thesis

Call Number: Thesis Shelf

Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation…

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Website: http://hdl.handle.net/2429/4814

Author: Katagiri, Seiji

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 1996

Subject: Faculty of Medicine; Theses

Abstract: Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation in the rat. IGF-I may be beneficial to preimplantation embryonic development. IGF-I stimulated embryonic development and metabolism in vitro and increased the rate of implantation and fetal development when the blastocysts were transferred into a receptive uterus.