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3 records – page 1 of 1.

Inhibition of pulsatile luteinizing hormone release by atrial natriuretic peptide and brain natriuretic peptide in the ovariectomized rat

https://cwslc.andornot.com/en/permalink/catalog113992
Zhang, Jin. [Vancouver, BC?]: University of British Columbia , 1990.
Website
http://hdl.handle.net/2429/29412
Material Type
Thesis
Call Number
Thesis Shelf
Atrial natriuretic peptide (ANP) of atrial myocyte origin, has been shown to play a role in the diuresis, natriuresis, and antagonism of angiotensin and vasopressin. However, it is now apparent that in addition to the production of the peptide in the heart and in its role in fluid and electrolyte h…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/29412
Author
Zhang, Jin
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1990
Subject
Faculty of Medicine
Theses
Abstract
Atrial natriuretic peptide (ANP) of atrial myocyte origin, has been shown to play a role in the diuresis, natriuresis, and antagonism of angiotensin and vasopressin. However, it is now apparent that in addition to the production of the peptide in the heart and in its role in fluid and electrolyte homeostasis, it is also produced in the central nervous system participating in the regulation of pituitary hormone secretion. Administration of ANP through both central and peripheral routes has been shown to inhibit secretion of luteinizing hormone (LH) in the gonadectomized rat model.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/29412
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The role for insulin-like growth factor-I in preimplantation embryonic development and decidualization following superovulation in the rat

https://cwslc.andornot.com/en/permalink/catalog113980
Katagiri, Seiji. [Vancouver, BC?]: University of British Columbia , 1996.
Website
http://hdl.handle.net/2429/4814
Material Type
Thesis
Call Number
Thesis Shelf
Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/4814
Author
Katagiri, Seiji
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1996
Subject
Faculty of Medicine
Theses
Abstract
Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation in the rat. IGF-I may be beneficial to preimplantation embryonic development. IGF-I stimulated embryonic development and metabolism in vitro and increased the rate of implantation and fetal development when the blastocysts were transferred into a receptive uterus.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/4814
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A morphological investigation of the effects of pregnant mare serum gonadotrophin on oocyte maturation, fertilization and embryonic development in rats

https://cwslc.andornot.com/en/permalink/catalog113990
Britton, Ann Patricia. [Vancouver, BC?]: University of British Columbia , 1991.
Website
http://hdl.handle.net/2429/30962
Material Type
Thesis
Call Number
Thesis Shelf
A delicate balance of steroid and gonadotrophic hormones is essential for intrafollicular oocyte maturation and successful fertilization and embryonic development. Previous studies have demonstrated that a superovulatory dose of pregnant mare serum gonadotrophin (PMSG) has excessive gonadotrophic a…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/30962
Author
Britton, Ann Patricia
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1991
Subject
Faculty of Medicine
Theses
Abstract
A delicate balance of steroid and gonadotrophic hormones is essential for intrafollicular oocyte maturation and successful fertilization and embryonic development. Previous studies have demonstrated that a superovulatory dose of pregnant mare serum gonadotrophin (PMSG) has excessive gonadotrophic activity and alters intrafol1icular steroid hormone levels. In a series of four experiments, the morphology of oocytes and embryos retrieved from immature rats, treated with either a low or high dose of PMSG, and mature, cycling rats was compared to determine whether a superovulatory dose of PMSG has an adverse effect on oocyte maturation and subsequent fertilization and embryonic development in immature rats. Morphological criteria for the assessment of intraoviductal oocyte aging were established in the first experiment.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/30962
Show Less