Website

http://hdl.handle.net/2429/30417

Author

Van der Weyde, Marlene

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

1990

Subject

Faculty of Medicine

Theses

Abstract

Ritodrine is a beta-adrenergic agonist commonly used to inhibit premature labor contractions in women. The primary goal of ritodrine tocolysis is to prolong gestation, however, other indications may include fetal distress. The purpose of the current study was to examine the metabolic and behavioral effects of ritodrine in the fetus, using the chronically instrumented pregnant sheep as an experimental model. Ritodrine was infused continuously into 11 fetal lambs at a rate of 2.6 ug/minute for a period of 8, 12 or 24 hours. Samples were taken simultaneously at predetermined time periods from a fetal femoral artery, umbilical vein, maternal femoral artery and uterine vein for the analysis of fetal and maternal arterial and umbilical and uterine venous blood gases, acid-base status, hematocrit, ritodrine concentration, uterine and umbilical blood flow, and glucose, lactate and oxygen concentrations and fluxes.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Author

Abrahams, P.H.

Hutchings, R.T.

Marks Jr, S.C.

Edition

4th ed.

Place of Publication

Philadelphia, PA

Publisher

Mosby

Publication Date

1998

Physical Description

Hardcover: 334 p.

Subject

Anatomy

Anatomy-Atlases. Pictorial Works

Language

English

Material Type

Book

Call Number

REF AC 205 ABR 1998

Copies