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Physical and functional interaction of p53 and p110a and implications in ovarian carcinogenesis

https://cwslc.andornot.com/en/permalink/catalog113967
Astanehe, Arezoo. [Vancouver, BC?]: University of British Columbia , 2005.
Website
http://hdl.handle.net/2429/16421
Material Type
Thesis
Call Number
Thesis Shelf
n approximately 40% of ovarian cancers, PIK3CA, which encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K) is amplified. This amplification correlates with increased PIK3CA transcription, p110α protein expression, and PI3K activity. Moreover, PIK3CA is implicated as…
Website
http://hdl.handle.net/2429/16421
Author
Astanehe, Arezoo
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2005
Subject
Faculty of Medicine
Theses
Abstract
n approximately 40% of ovarian cancers, PIK3CA, which encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K) is amplified. This amplification correlates with increased PIK3CA transcription, p110α protein expression, and PI3K activity. Moreover, PIK3CA is implicated as an oncogene in ovarian cancers. Another common mutation in ovarian cancer leads to loss of p53 function. Alterations to p53 are known to be involved in tumour development and progression.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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The toyota way to healthcare excellence: Increase efficiency and improve quality with Lean

https://cwslc.andornot.com/en/permalink/catalog112895
Black, John R., Miller, David. Chicago, IL: Health Administration Press , 2008.
Material Type
Book
Call Number
REF AA 120 BLA 2008
Availability
22 copies, 20 available
This straightforward guide explains what Lean is, how it works, and how to implement the strategy at your organization.
Author
Black, John R.
Miller, David
Place of Publication
Chicago, IL
Publisher
Health Administration Press
Publication Date
2008
Physical Description
Softcover: 255 p.
Subject
Lean Leader Development
Abstract
This straightforward guide explains what Lean is, how it works, and how to implement the strategy at your organization.
ISBN
9781567932935
Language
English
Material Type
Book
Call Number
REF AA 120 BLA 2008

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