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The role for insulin-like growth factor-I in preimplantation embryonic development and decidualization following superovulation in the rat

https://cwslc.andornot.com/en/permalink/catalog113980
Katagiri, Seiji. [Vancouver, BC?]: University of British Columbia , 1996.
Website
http://hdl.handle.net/2429/4814
Material Type
Thesis
Call Number
Thesis Shelf
Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation…
Website
http://hdl.handle.net/2429/4814
Author
Katagiri, Seiji
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1996
Subject
Faculty of Medicine
Theses
Abstract
Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation in the rat. IGF-I may be beneficial to preimplantation embryonic development. IGF-I stimulated embryonic development and metabolism in vitro and increased the rate of implantation and fetal development when the blastocysts were transferred into a receptive uterus.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
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The effects of clomiphene citrate on ovarian function in rats

https://cwslc.andornot.com/en/permalink/catalog113993
Feng, Tian Bin. [Vancouver, BC?]: University of British Columbia , 1990.
Website
http://hdl.handle.net/2429/28984
Material Type
Thesis
Call Number
Thesis Shelf
In the present study, the effects of clomiphene citrate (CC) on ovulation, ovarian growth and ovarian steroidogenesis were examined. Ovulation in rats in response to PMSG was completely blocked by administration of three daily treatments of 1.0 mg CC/rat, but was restored by administration of hCG a…
Website
http://hdl.handle.net/2429/28984
Author
Feng, Tian Bin
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1990
Subject
Faculty of Medicine
Theses
Abstract
In the present study, the effects of clomiphene citrate (CC) on ovulation, ovarian growth and ovarian steroidogenesis were examined. Ovulation in rats in response to PMSG was completely blocked by administration of three daily treatments of 1.0 mg CC/rat, but was restored by administration of hCG as a preovulatory LH surge substitute. When the number of treatment days was reduced to two days, 1.0 mg of CC enhanced ovulation in response to PMSG, whereas treatment for one day with the same dose of CC did not affect ovulation.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less