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Physical and functional interaction of p53 and p110a and implications in ovarian carcinogenesis

https://cwslc.andornot.com/en/permalink/catalog113967
Astanehe, Arezoo. [Vancouver, BC?]: University of British Columbia , 2005.
Website
http://hdl.handle.net/2429/16421
Material Type
Thesis
Call Number
Thesis Shelf
n approximately 40% of ovarian cancers, PIK3CA, which encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K) is amplified. This amplification correlates with increased PIK3CA transcription, p110α protein expression, and PI3K activity. Moreover, PIK3CA is implicated as…
Website
http://hdl.handle.net/2429/16421
Author
Astanehe, Arezoo
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2005
Subject
Faculty of Medicine
Theses
Abstract
n approximately 40% of ovarian cancers, PIK3CA, which encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K) is amplified. This amplification correlates with increased PIK3CA transcription, p110α protein expression, and PI3K activity. Moreover, PIK3CA is implicated as an oncogene in ovarian cancers. Another common mutation in ovarian cancer leads to loss of p53 function. Alterations to p53 are known to be involved in tumour development and progression.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Toronto notes 2010: Comprehensive medical reference and review for MCCQE I & USMLE II

https://cwslc.andornot.com/en/permalink/catalog112655
Baxter, Simon, McSheffrey, Gordon. [Toronto, ON]: Toronto Notes for Medical Students, Inc. , 2010. 26th ed.
Material Type
Book
Call Number
REF AB 22 TOR 2010
Availability
1 copy, 1 available
The classic Canadian compilation of notes to assist medical students in studying for the MCCQE I and USMLE II exams.
Author
Baxter, Simon
McSheffrey, Gordon
Edition
26th ed.
Place of Publication
[Toronto, ON]
Publisher
Toronto Notes for Medical Students, Inc.
Publication Date
2010
Physical Description
Softcover: [alternative paging]
Subject
Medical Directories. Resource Guides
UBC MD Undergrad
Abstract
The classic Canadian compilation of notes to assist medical students in studying for the MCCQE I and USMLE II exams.
ISBN
9780980939729
Language
English
Material Type
Book
Call Number
REF AB 22 TOR 2010

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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