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2 records – page 1 of 1.

Physical and functional interaction of p53 and p110a and implications in ovarian carcinogenesis

https://cwslc.andornot.com/en/permalink/catalog113967
Astanehe, Arezoo. [Vancouver, BC?]: University of British Columbia , 2005.
Website
http://hdl.handle.net/2429/16421
Material Type
Thesis
Call Number
Thesis Shelf
n approximately 40% of ovarian cancers, PIK3CA, which encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K) is amplified. This amplification correlates with increased PIK3CA transcription, p110α protein expression, and PI3K activity. Moreover, PIK3CA is implicated as…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/16421
Author
Astanehe, Arezoo
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2005
Subject
Faculty of Medicine
Theses
Abstract
n approximately 40% of ovarian cancers, PIK3CA, which encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K) is amplified. This amplification correlates with increased PIK3CA transcription, p110α protein expression, and PI3K activity. Moreover, PIK3CA is implicated as an oncogene in ovarian cancers. Another common mutation in ovarian cancer leads to loss of p53 function. Alterations to p53 are known to be involved in tumour development and progression.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/16421
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Clinical neurology

https://cwslc.andornot.com/en/permalink/catalog112841
Greenberg, David A.,, Aminoff, Michael J. &, Simon, Roger P. New York, NY: McGraw Hill , 2012. 8th Ed.
Material Type
Book
Call Number
REF FM 100 GRE 2012
Availability
1 copy, 1 available
This text helps students, residents and clinicians understand the link between basic neuroscience and current approaches to diagnosis and treatment.
More Information is Available
Author
Greenberg, David A.,
Aminoff, Michael J. &
Simon, Roger P.
Edition
8th Ed.
Place of Publication
New York, NY
Publisher
McGraw Hill
Publication Date
2012
Physical Description
Paperback: p 441.
Subject
Brain
Nervous System/Nervous System Diseases. Neurology
UBC MD Undergrad
Abstract
This text helps students, residents and clinicians understand the link between basic neuroscience and current approaches to diagnosis and treatment.
ISBN
978-0-07-175905-2
Language
English
Material Type
Book
Call Number
REF FM 100 GRE 2012

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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