Website

http://hdl.handle.net/2429/16421

Author

Astanehe, Arezoo

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2005

Subject

Faculty of Medicine

Theses

Abstract

n approximately 40% of ovarian cancers, PIK3CA, which encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K) is amplified. This amplification correlates with increased PIK3CA transcription, p110α protein expression, and PI3K activity. Moreover, PIK3CA is implicated as an oncogene in ovarian cancers. Another common mutation in ovarian cancer leads to loss of p53 function. Alterations to p53 are known to be involved in tumour development and progression.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Author

Blackburn, Susan Tucker

Edition

3rd ed.

Place of Publication

St. Louis, MI

Publisher

Saunders Elsevier

Publication Date

2007

Physical Description

Hardcover: 723 p.

Subject

Neonatal Assessment

Pregnancy/Childbirth. Obstetrics

Fetal Monitoring

Physiology

UBC MD Undergrad

Abstract

This text details the changes in physiology that occur throughout all major periods of the perinatal experience - prenatal, intrapartum, postpartum, and neonatal. This text provides a solid foundation for assessment and therapeutic interventions, featuring an emphasis on the evolving interrelationships between mother, fetus, and neonate and adaptations of preterm and term infants to the extrauterine environment. This edition offers a chapter on fetal assessment and surveillance, as well as expanded coverage of the physiologic basis for reproduction.

ISBN

9781416029441

Language

English

Material Type

Book

Call Number

REF GH 100 BLA 2007

Copies