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9 records – page 1 of 1.

Human gene therapy

https://cwslc.andornot.com/en/permalink/catalog119691
Website
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=Human+gene+therapy
Place of Publication
Baltimore, MD
Publisher
Mary Ann Liebert, Inc.
Publication Date
1990 - Present
ISSN
1043-0342
Language
English
Material Type
Serial
Frequency
Monthly
Holdings
CFRI/Study & Learning Commons - Print: v.5:9 (1994); v.6:1-v.13:18 (1995-2002).
Missing: v.8:8 (1997); v.10:17 (1999); v.11:3,4,6-18 (2000); v.12:1-12,14,17,18 (2001); v.13:5 (2002).
Online: 2006 to 2014.
Websites
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Recombinant human activated protein C as a therapy for pre-eclampsia

https://cwslc.andornot.com/en/permalink/catalog113962
Peng, Gang. [Vancouver, BC?]: University of British Columbia , 2007.
Website
http://hdl.handle.net/2429/32051
Material Type
Thesis
Call Number
Thesis Shelf
Pre-eclampsia remains one of the most common causes of maternal mortality in the developed world, and we still have no known effective prophylaxis and proven modifiers. The recent successful clinical trial of recombinant human activated protein C (rhAPC) in the management of SIRS (systemic inflamma…
Website
http://hdl.handle.net/2429/32051
Author
Peng, Gang
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2007
Subject
Faculty of Medicine
Theses
Abstract
Pre-eclampsia remains one of the most common causes of maternal mortality in the developed world, and we still have no known effective prophylaxis and proven modifiers. The recent successful clinical trial of recombinant human activated protein C (rhAPC) in the management of SIRS (systemic inflammatory response syndrome) has drawn attention to the possible use of this medicine for other conditions. Pre-eclampsia, has remarkable similarity to SIRS and may be such a condition.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Genes & development

https://cwslc.andornot.com/en/permalink/catalog119625
Cold Spring Harbor Laboratory., Genetical Society (Great Britain). Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press , 1987 - Present.
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp30646&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=Genes+%26+Development
Material Type
Serial
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp30646&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=Genes+%26+Development
Alternate Title
Genes and development
Corporate Author
Cold Spring Harbor Laboratory.
Genetical Society (Great Britain)
Place of Publication
Cold Spring Harbor, N.Y.
Publisher
Cold Spring Harbor Laboratory Press
Publication Date
1987 - Present
ISSN
0890-9369
Language
English
Material Type
Serial
Frequency
Biweekly
Holdings
CFRI/Study & Learning Commons - Print: v.8:4-v.17:17 (1994-2003).
Missing: v.8:6 (1994); v.9:5 (1995); v.13:21 (1999); v.14:22 (2000); v.15:13,16,18,24 (2001); v.16:1,6 (2002).
Online: 1987 to present.
Websites
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Characterization of the human gonadotropin-releasing hormone receptor gene at the molecular level

https://cwslc.andornot.com/en/permalink/catalog113982
Fan, Nancy C. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7255
Material Type
Thesis
Call Number
Thesis Shelf
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling sti…
Website
http://hdl.handle.net/2429/7255
Author
Fan, Nancy C.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling stimulates the synthesis and release of both luteinizing hormone and follicle stimulating hormone from the anterior pituitary. In addition, GnRH - GnRH receptor binding acts locally to regulate human chorionic gonadotropin secretion in the placenta and steroidogenesis in the ovary. The objective of this thesis was to isolate and characterize the gene for the GnRH receptor in human.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Investigation of methylation and gene expression in placenta of pregnancies conceived by assisted reproductive technology (ART)

https://cwslc.andornot.com/en/permalink/catalog113947
Sakian, Sina. [Vancouver, BC?]: University of British Columbia , 2011.
Website
http://hdl.handle.net/2429/31191
Material Type
Thesis
Call Number
Thesis Shelf
With the increasing use of assisted reproductive techniques (ART) every year, concerns have been raised regarding the possible effect these procedures have on the health of the children procured by them. Although patients born via ART are usually healthy, studies have associated these procedures wi…
Website
http://hdl.handle.net/2429/31191
Author
Sakian, Sina
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2011
Subject
Faculty of Medicine
Theses
Abstract
With the increasing use of assisted reproductive techniques (ART) every year, concerns have been raised regarding the possible effect these procedures have on the health of the children procured by them. Although patients born via ART are usually healthy, studies have associated these procedures with increased incidence of low birth weight (LBW), chromosomal abnormalities, birth defects and imprinting disorders. No study has proposed a single defined cause for any of these defects in ART infants, however it is believed that they may be due to both the invasiveness of ART and to genetic defects that are at the root of the infertility in the parents. In this study, changes in the methylation of the H19 and IGF2 imprinting control region 1 (ICR1) were investigated for both ART (n=92) and naturally conceived controls (n=19) using pyrosequencing.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Expression and function of HOXA genes in the normal ovary and ovarian carcinoma

https://cwslc.andornot.com/en/permalink/catalog113963
Ota, Takayo. [Vancouver, BC?]: University of British Columbia , 2006.
Website
http://hdl.handle.net/2429/30974
Material Type
Thesis
Call Number
Thesis Shelf
Homeobox genes, which code for families of transcription factors, act at the top of genetic hierarchies. HOX genes specify positional identity during development, and in adult tissues, regulate differentiation and proliferation. Most ovarian carcinomas are derived from the ovarian surface epitheliu…
Website
http://hdl.handle.net/2429/30974
Author
Ota, Takayo
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2006
Subject
Faculty of Medicine
Theses
Abstract
Homeobox genes, which code for families of transcription factors, act at the top of genetic hierarchies. HOX genes specify positional identity during development, and in adult tissues, regulate differentiation and proliferation. Most ovarian carcinomas are derived from the ovarian surface epithelium (OSE). In contrast to other carcinomas, OSE differentiates further with neoplastic progression and acquires Mtillerian duct-derived epithelial properties. I tested the hypothesis that growth and differentiation in ovarian carcinogenesis are regulated by HOX genes.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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DNA methylation at imprinted and non-imprinted genes in the sperm of men affected by severe male factor infertility

https://cwslc.andornot.com/en/permalink/catalog113950
Minor, Agata. [Vancouver, BC?]: University of British Columbia , 2010.
Website
http://hdl.handle.net/2429/29282
Material Type
Thesis
Call Number
Thesis Shelf
Abnormal DNA methylation at imprinted and non-imprinted genes has been associated with spermatogenesis failure. However, little information is available regarding DNA methylation at those genes in men affected by severe male factor infertility. We hypothesized a higher incidence of aberrant DNA met…
Website
http://hdl.handle.net/2429/29282
Author
Minor, Agata
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2010
Subject
Faculty of Medicine
Theses
Abstract
Abnormal DNA methylation at imprinted and non-imprinted genes has been associated with spermatogenesis failure. However, little information is available regarding DNA methylation at those genes in men affected by severe male factor infertility. We hypothesized a higher incidence of aberrant DNA methylation would be present in the ejaculate and testicular sperm of men affected by severe male factor infertility compared to that in fertile control men. Furthermore, we hypothesized abnormal DNA methylation would also affect non-imprinted genes in the sperm of men affected by severe oligozoospermia.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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9 records – page 1 of 1.