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Characterization of the human gonadotropin-releasing hormone receptor gene at the molecular level

https://cwslc.andornot.com/en/permalink/catalog113982

Fan, Nancy C. [Vancouver, BC?]: University of British Columbia , 1995.

Website: http://hdl.handle.net/2429/7255

Material Type: Thesis

Call Number: Thesis Shelf

The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling sti…

1 website

Website: http://hdl.handle.net/2429/7255

Author: Fan, Nancy C.

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 1995

Subject: Faculty of Medicine; Theses

Abstract: The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling stimulates the synthesis and release of both luteinizing hormone and follicle stimulating hormone from the anterior pituitary. In addition, GnRH - GnRH receptor binding acts locally to regulate human chorionic gonadotropin secretion in the placenta and steroidogenesis in the ovary. The objective of this thesis was to isolate and characterize the gene for the GnRH receptor in human.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

Websites

http://hdl.handle.net/2429/7255

The effects of clomiphene citrate on ovarian function in rats

https://cwslc.andornot.com/en/permalink/catalog113993

Feng, Tian Bin. [Vancouver, BC?]: University of British Columbia , 1990.

Website: http://hdl.handle.net/2429/28984

Material Type: Thesis

Call Number: Thesis Shelf

In the present study, the effects of clomiphene citrate (CC) on ovulation, ovarian growth and ovarian steroidogenesis were examined. Ovulation in rats in response to PMSG was completely blocked by administration of three daily treatments of 1.0 mg CC/rat, but was restored by administration of hCG a…

1 website

Website: http://hdl.handle.net/2429/28984

Author: Feng, Tian Bin

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 1990

Subject: Faculty of Medicine; Theses

Abstract: In the present study, the effects of clomiphene citrate (CC) on ovulation, ovarian growth and ovarian steroidogenesis were examined. Ovulation in rats in response to PMSG was completely blocked by administration of three daily treatments of 1.0 mg CC/rat, but was restored by administration of hCG as a preovulatory LH surge substitute. When the number of treatment days was reduced to two days, 1.0 mg of CC enhanced ovulation in response to PMSG, whereas treatment for one day with the same dose of CC did not affect ovulation.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

Websites

http://hdl.handle.net/2429/28984