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2 records – page 1 of 1.

Regulation of cytochrome P450 and P450 mRNA in human granulosa-luteal cells

https://cwslc.andornot.com/en/permalink/catalog113984
Ge, Hong. [Vancouver, BC?]: University of British Columbia , 1994.
Website
http://hdl.handle.net/2429/3482
Material Type
Thesis
Call Number
Thesis Shelf
This thesis investigated the expression and regulation of cytochrome P450s, aromatase (P450arom) and cholesterol side chain cleavage (P450scc) enzyme mRNAs in human granulosa-luteal cells using reverse transcription-polymerase chain reaction (RT-PCR). The two enzymes are instrumental in steroid hor…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/3482
Author
Ge, Hong
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1994
Subject
Faculty of Medicine
Theses
Abstract
This thesis investigated the expression and regulation of cytochrome P450s, aromatase (P450arom) and cholesterol side chain cleavage (P450scc) enzyme mRNAs in human granulosa-luteal cells using reverse transcription-polymerase chain reaction (RT-PCR). The two enzymes are instrumental in steroid hormone biosynthesis.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/3482
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A morphological investigation of the effects of pregnant mare serum gonadotrophin on oocyte maturation, fertilization and embryonic development in rats

https://cwslc.andornot.com/en/permalink/catalog113990
Britton, Ann Patricia. [Vancouver, BC?]: University of British Columbia , 1991.
Website
http://hdl.handle.net/2429/30962
Material Type
Thesis
Call Number
Thesis Shelf
A delicate balance of steroid and gonadotrophic hormones is essential for intrafollicular oocyte maturation and successful fertilization and embryonic development. Previous studies have demonstrated that a superovulatory dose of pregnant mare serum gonadotrophin (PMSG) has excessive gonadotrophic a…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/30962
Author
Britton, Ann Patricia
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1991
Subject
Faculty of Medicine
Theses
Abstract
A delicate balance of steroid and gonadotrophic hormones is essential for intrafollicular oocyte maturation and successful fertilization and embryonic development. Previous studies have demonstrated that a superovulatory dose of pregnant mare serum gonadotrophin (PMSG) has excessive gonadotrophic activity and alters intrafol1icular steroid hormone levels. In a series of four experiments, the morphology of oocytes and embryos retrieved from immature rats, treated with either a low or high dose of PMSG, and mature, cycling rats was compared to determine whether a superovulatory dose of PMSG has an adverse effect on oocyte maturation and subsequent fertilization and embryonic development in immature rats. Morphological criteria for the assessment of intraoviductal oocyte aging were established in the first experiment.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/30962
Show Less