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Physical and functional interaction of p53 and p110a and implications in ovarian carcinogenesis

https://cwslc.andornot.com/en/permalink/catalog113967
Astanehe, Arezoo. [Vancouver, BC?]: University of British Columbia , 2005.
Website
http://hdl.handle.net/2429/16421
Material Type
Thesis
Call Number
Thesis Shelf
n approximately 40% of ovarian cancers, PIK3CA, which encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K) is amplified. This amplification correlates with increased PIK3CA transcription, p110α protein expression, and PI3K activity. Moreover, PIK3CA is implicated as…
Website
http://hdl.handle.net/2429/16421
Author
Astanehe, Arezoo
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2005
Subject
Faculty of Medicine
Theses
Abstract
n approximately 40% of ovarian cancers, PIK3CA, which encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K) is amplified. This amplification correlates with increased PIK3CA transcription, p110α protein expression, and PI3K activity. Moreover, PIK3CA is implicated as an oncogene in ovarian cancers. Another common mutation in ovarian cancer leads to loss of p53 function. Alterations to p53 are known to be involved in tumour development and progression.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Mastering leadership: An integrated framework for breakthrough performance and extraordinary business results

https://cwslc.andornot.com/en/permalink/catalog113746
Anderson, Robert J., Adams, William A. Hoboken, NJ: Wiley , 2016.
Material Type
Book
Call Number
REF AA 75 AND 2016
Availability
3 copies, 3 available
For most leaders today, complexity is outpacing their personal and collective development. Most leaders are in over their heads, whether they know it or not. The most successful organizations over time are the best led. While this has always been true, today escalating global complexity puts leader…
Author
Anderson, Robert J.
Adams, William A.
Place of Publication
Hoboken, NJ
Publisher
Wiley
Publication Date
2016
Subject
Leadership/Coaching
Abstract
For most leaders today, complexity is outpacing their personal and collective development. Most leaders are in over their heads, whether they know it or not. The most successful organizations over time are the best led. While this has always been true, today escalating global complexity puts leadership effectiveness at a premium. Mastering Leadership involves developing the effectiveness of leaders?individually and collectively?and turning that leadership into a competitive advantage.
ISBN
9781119147190
Language
English
Material Type
Book
Call Number
REF AA 75 AND 2016

Copies

Copy 1 BC Children's and Women's Study and Learning Commons Available
Copy 2 BC Children's and Women's Study and Learning Commons Available
Copy 3 BC Children's and Women's Study and Learning Commons Available
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