Website

PHSA Users:

http://web.b.ebscohost.com/pfi/detail/detail?vid=2&sid=1ca4387a-7b18-48a7-8383-517069a00ce3%40sessionmgr101&hid=118&bdata=JnNpdGU9cGZpLWxpdmU%3d#AN=edp3739&db=edspub

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?sid=sersol&SS_jc=AMERJOUROFHU&title=American%20journal%20of%20human%20genetics

Alternate Title

AJHG

Corporate Author

The American Society of Human Genetics

Publisher

Cell Press

ISSN

0002-9297

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.4:1-v.97:6 (1994-2012);

v.93:12-v.94:1 + suppls. (2013-2014)

Missing: v.59:3-5 (1996); v.61:1(1997); v.80:2(2007); v.85:2(2009); v.91:4-5(2009)

Online: 1949 to present (Full Text Delay: 6 months)

Website

PHSA Users:

http://web.a.ebscohost.com/pfi/detail/detail?vid=12&sid=4b03aa3d-52ba-418e-83aa-912631ff2be1%40sessionmgr4005&hid=4209&bdata=JnNpdGU9cGZpLWxpdmU%3d#AN=edp9502&db=edspub

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=Behavior+Genetics

Corporate Author

Behavior Genetics Association

Place of Publication

New York, NY

Publisher

Springer International Publishing AG in cooperation with the Behavior Genetics Association

Publication Date

1970-

ISSN

0001-8244

Language

English

Material Type

Serial

Frequency

Bimonthly

Holdings

CFRI/Study & Learning Commons - Print: v.28:3-6 (1998);

v.29:1 (1999);

v.29:2-6 (1999);

v.31:1-v.36:6 (2001-2006;

v.38:1-5 (2008).

Online: 1997 to present

Website

http://hdl.handle.net/2429/7255

Author

Fan, Nancy C.

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

1995

Subject

Faculty of Medicine

Theses

Abstract

The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling stimulates the synthesis and release of both luteinizing hormone and follicle stimulating hormone from the anterior pituitary. In addition, GnRH - GnRH receptor binding acts locally to regulate human chorionic gonadotropin secretion in the placenta and steroidogenesis in the ovary. The objective of this thesis was to isolate and characterize the gene for the GnRH receptor in human.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

PHSA Users:

http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp18084&site=pfi-live

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=clinical+genetics

Place of Publication

Malden, Ma.

Publisher

John Wiley & Sons, Inc.

Publication Date

1970 - Present.

ISSN

0009-9163

Language

English

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.45:6-v.57:4+special issue (1994-2000); v.61:1 (2002); v.69:3-v.76:3 (2006-2009).

Missing: v.51:3, v.52:4 (1997); v.53:2 (1998); v.55:4, v.56:1,3 (1999); v.57:1-3, v.58:1-6 (2000); v.59:1-6, v.60:1-6 (2001); v.61:2-6, v.62:1-6 (2002); 2003-2005; v.69:1-2 (2006); v.73:3-5 (2008); v.75:1,3,4, v.76:2,4-6 (2009).

Online: 1970 to present.

Website

http://hdl.handle.net/2429/29282

Author

Minor, Agata

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2010

Subject

Faculty of Medicine

Theses

Abstract

Abnormal DNA methylation at imprinted and non-imprinted genes has been associated with spermatogenesis failure. However, little information is available regarding DNA methylation at those genes in men affected by severe male factor infertility. We hypothesized a higher incidence of aberrant DNA methylation would be present in the ejaculate and testicular sperm of men affected by severe male factor infertility compared to that in fertile control men. Furthermore, we hypothesized abnormal DNA methylation would also affect non-imprinted genes in the sperm of men affected by severe oligozoospermia.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

http://hdl.handle.net/2429/30974

Author

Ota, Takayo

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2006

Subject

Faculty of Medicine

Theses

Abstract

Homeobox genes, which code for families of transcription factors, act at the top of genetic hierarchies. HOX genes specify positional identity during development, and in adult tissues, regulate differentiation and proliferation. Most ovarian carcinomas are derived from the ovarian surface epithelium (OSE). In contrast to other carcinomas, OSE differentiates further with neoplastic progression and acquires Mtillerian duct-derived epithelial properties. I tested the hypothesis that growth and differentiation in ovarian carcinogenesis are regulated by HOX genes.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

PHSA Users:

http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp30655&site=pfi-live

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=Genes%2C+Brain+and+Behavior

Alternate Title

G2B

Corporate Author

International Behavioural and Neural Genetics Society

Place of Publication

Malden, Ma.

Publisher

Wiley-Blackwell

Publication Date

2002 - Present

ISSN

1601-1848

Language

English

Material Type

Serial

Frequency

Irregular or Other

Holdings

CFRI/Study & Learning Commons - Print: v.3-v.6:8 (2004-2007).

Online: 2002 to present.

Website

PHSA Users:

http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp30646&site=pfi-live

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=Genes+%26+Development

Alternate Title

Genes and development

Corporate Author

Cold Spring Harbor Laboratory.

Genetical Society (Great Britain)

Place of Publication

Cold Spring Harbor, N.Y.

Publisher

Cold Spring Harbor Laboratory Press

Publication Date

1987 - Present

ISSN

0890-9369

Language

English

Material Type

Serial

Frequency

Biweekly

Holdings

CFRI/Study & Learning Commons - Print: v.8:4-v.17:17 (1994-2003).

Missing: v.8:6 (1994); v.9:5 (1995); v.13:21 (1999); v.14:22 (2000); v.15:13,16,18,24 (2001); v.16:1,6 (2002).

Online: 1987 to present.

Website

PHSA Users:

http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp30593&site=pfi-live

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=Gene+Therapy

Place of Publication

Baltimore, MD

Publisher

Nature Publishing Group

Publication Date

1994 - Present

ISSN

0969-7128

Language

English

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.1:2-v.12:14,17,19-22,24 (1994-2005); + suppls.

Missing: v.8:23 (2001); v.9:5,8,20,24 (2002); v.10:22-26 (2003); v.11:11,15,19,20 (2004); v.12:1,3,5,15,16,18,23 (2005).

Online: 1997 to present.

Website

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=Human+gene+therapy

Place of Publication

Baltimore, MD

Publisher

Mary Ann Liebert, Inc.

Publication Date

1990 - Present

ISSN

1043-0342

Language

English

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.5:9 (1994); v.6:1-v.13:18 (1995-2002).

Missing: v.8:8 (1997); v.10:17 (1999); v.11:3,4,6-18 (2000); v.12:1-12,14,17,18 (2001); v.13:5 (2002).

Online: 2006 to 2014.

Website

PHSA Users:

http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp33596&site=pfi-live

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=human+molecular+genetics

Place of Publication

Oxford, England

Publisher

Oxford University Press

Publication Date

1992 - Present

ISSN

0964-6906

Language

English

Material Type

Serial

Frequency

Bimonthly

Holdings

CFRI/Study & Learning Commons - Print: v.3:1-v.8:13 (1994-1999); v.9:15-16 (2000); v.10:1-16,19,20,22-25 (2001); v.11:17,20 (2002); v.12:13 (2003).

Missing: v.4:8 (1995); v.5:8 (1996); v.6:8,10 (1997).

Online: 1992 to present.

Website

http://hdl.handle.net/2429/31191

Author

Sakian, Sina

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2011

Subject

Faculty of Medicine

Theses

Abstract

With the increasing use of assisted reproductive techniques (ART) every year, concerns have been raised regarding the possible effect these procedures have on the health of the children procured by them. Although patients born via ART are usually healthy, studies have associated these procedures with increased incidence of low birth weight (LBW), chromosomal abnormalities, birth defects and imprinting disorders. No study has proposed a single defined cause for any of these defects in ART infants, however it is believed that they may be due to both the invasiveness of ART and to genetic defects that are at the root of the infertility in the parents. In this study, changes in the methylation of the H19 and IGF2 imprinting control region 1 (ICR1) were investigated for both ART (n=92) and naturally conceived controls (n=19) using pyrosequencing.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

PHSA Users:

http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp41514&site=pfi-live

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=Journal+of+Medical+Genetics

Alternate Title

J. Med. Genet.

Place of Publication

London, United Kingdom of Great Britain & Northern Ireland

Publisher

BMJ Publishing Group

Publication Date

1964 - Present

ISSN

0022-2593

Language

English

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.30:12-v.40:1+suppls. (1993-2003).

Missing: v.31:12 (1994); v.37:4 (2000).

Online: 1964 to present.

Website

http://www.ncbi.nlm.nih.gov/omim

Website Notes

The database corresponds to the print publication.

Author

McKusiak, Victor A (Ed).

Edition

12th Ed.

Place of Publication

Baltimore, MD

Publisher

Johns Hopkins University Press

Publication Date

1998

Physical Description

Hardcover

Subject

Genetics

Genetic Disorders

Genetics/Genetic Disorders-Encyclopedias

Abstract

A comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics.

ISBN

0801857422

Language

English

Material Type

Book

Call Number

REF GI 20 MCK 1998 VOL 1

Copies

Website

http://www.ncbi.nlm.nih.gov/omim

Website Notes

The database corresponds to the print publication.

Author

McKusiak, Victor A (Ed).

Edition

12th Ed.

Place of Publication

Baltimore, MD

Publisher

Johns Hopkins University Press

Publication Date

1998

Physical Description

Hardcover

Subject

Genetics

Genetics/Genetic Disorders-Encyclopedias

Genetic Disorders

Abstract

A comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics.

ISBN

0801857422

Language

English

Material Type

Book

Call Number

REF GI 20 MCK 1998 VOL 2

Copies

Website

http://www.ncbi.nlm.nih.gov/omim

Website Notes

The database corresponds to the print publication.

Author

McKusiak, Victor A (Ed).

Place of Publication

Baltimore, MD

Publisher

Johns Hopkins University Press

Publication Date

1998

Physical Description

Hardcover

Subject

Genetic Disorders

Genetics

Genetics/Genetic Disorders-Encyclopedias

Abstract

A comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics.

ISBN

0801857422

Language

English

Material Type

Book

Call Number

REF GI 20 MCK 1998 VOL 3

Copies

Website

PHSA Users:

http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp50993&site=pfi-live

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=nature+genetics

Alternate Title

Nat. Genet.

Place of Publication

New York, NY

Publisher

Nature Publishing Group

Publication Date

1992 - Present.

ISSN

1061-4036

Language

English

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.6:1-v.46:6+suppls. (1994-2012).

Missing: v.11:1(1995); v.12:1 (1996); v.21:4; v.23:3 (1999); v.27:2; v.28:3 (2001); v.31:2; v.32:4 (2002); v.35:4 (2003).

Online: 1992 to present.

Website

http://hdl.handle.net/2429/16421

Author

Astanehe, Arezoo

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2005

Subject

Faculty of Medicine

Theses

Abstract

n approximately 40% of ovarian cancers, PIK3CA, which encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase (PI3K) is amplified. This amplification correlates with increased PIK3CA transcription, p110α protein expression, and PI3K activity. Moreover, PIK3CA is implicated as an oncogene in ovarian cancers. Another common mutation in ovarian cancer leads to loss of p53 function. Alterations to p53 are known to be involved in tumour development and progression.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

PHSA Users:

Not available online:

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=trends+in+genetics

Place of Publication

Cambridge, Ma.

Publisher

Elsevier Inc.

Publication Date

1985 - Present.

ISSN

0168-9525

Language

English

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.13:1-v.14:12 (1997-1998); v.15:1,10 (1999); v.16:4.10 (2000); v.17:1-11 (2001); v.18:2-4,6 (2002); v.22:5-9,11,12+suppls. (2006).

Missing: v.13:8 (1997); v.15:2-9,11,12 (1999); v.16:1-3,5-9,11,12 (2000); v.17:12 (2001); v.18:1,5,7-12 (2002); v.119-v.21 (2003-2005); v.22:1-4,10 (2006).

Online: 1985 to present.

Website

PHSA Users:

Not available online:

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=trends+in+genetics

Place of Publication

Cambridge, Ma.

Publisher

Elsevier Inc.

Publication Date

1985 - Present.

ISSN

0168-9525

Language

English

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.13:1-v.14:12 (1997-1998); v.15:1,10 (1999); v.16:4.10 (2000); v.17:1-11 (2001); v.18:2-4,6 (2002); v.22:5-9,11,12+suppls. (2006).

Missing: v.13:8 (1997); v.15:2-9,11,12 (1999); v.16:1-3,5-9,11,12 (2000); v.17:12 (2001); v.18:1,5,7-12 (2002); v.119-v.21 (2003-2005); v.22:1-4,10 (2006).

Online: 1985 to present.