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2015 handbook of emergency cardiovascular care for healthcare providers

https://cwslc.andornot.com/en/permalink/catalog113897
American Heart Association, Heart & Stroke Foundation. , 2015.
Material Type
Book
This handbook contains the 2015 Canadian guidelines for resuscitation and first aid. It is intended to be used by healthcare professionals in emergency, intensive care, or critical care departments; emergency medical care providers; first responders; and AHA and other healthcare instructors. The ha…
Author
American Heart Association
Heart & Stroke Foundation
Publication Date
2015
Physical Description
Pocket-sized, spiral bound, 6.25" x 4" book; 216 pages.
Abstract
This handbook contains the 2015 Canadian guidelines for resuscitation and first aid. It is intended to be used by healthcare professionals in emergency, intensive care, or critical care departments; emergency medical care providers; first responders; and AHA and other healthcare instructors. The handbook is organized into sections for basic, advanced adult, and pediatric life support and newborn resuscitation. It provides algorithms for BCLS, ACLS and PALS, protocols, sequences, drug dosages, and more.
ISBN
9781926969367
Language
English
Material Type
Book
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ACoRN: Acute care of at-risk newborns: A resource and learning tool for health care professionals

https://cwslc.andornot.com/en/permalink/catalog123249
Perinatal Services BC. [Vancouver, BC?]: McCallum Printing Group, Inc. , 2021. 2nd Edition.
Material Type
Book
Call Number
REF EB 800 ACO 2021
Availability
18 copies, 5 available
The Acute Care of at-Risk Newborns (ACoRN) program trains health care providers to stabilize that most challenging and enigmatic of medical patients: the unwell newborn. Early assessment, intervention, and management of at-risk or unstable infants can be critical for their survival and long-term he…
Author
Perinatal Services BC
Edition
2nd Edition
Place of Publication
[Vancouver, BC?]
Publisher
McCallum Printing Group, Inc.
Publication Date
2021
Physical Description
Hardcover: [437 p.]
Subject
Neonatal Assessment
Abstract
The Acute Care of at-Risk Newborns (ACoRN) program trains health care providers to stabilize that most challenging and enigmatic of medical patients: the unwell newborn. Early assessment, intervention, and management of at-risk or unstable infants can be critical for their survival and long-term health. Clinical care standards and educational programs to address these requirements are needed. ­The ACoRN program provides a unique, prioritized, and systematic approach to newborn stabilization for health care professionals with any degree of experience. ACoRN-trained providers learn to gather information, prioritize, intervene appropriately, and deliver high-quality care to at-risk and unwell newborns in any setting. Because research and practice have advanced dramatically in recent years, the need for a new ACoRN text, the program's centrepiece, became essential. Hence the development of this new edition, which reflects current guidelines and evidence-based best practices. ACoRN teaches the concepts and skills required to stabilize unwell newborns through system-based algorithms ('Sequences'), each with its own chapter: - Respiratory - Fluid and Glucose - Cardiovascular - Jaundice - Neurology - Thermoregulation - Surgical Conditions - Infection Each chapter includes educational objectives, key concepts, learning points, and at least one case scenario with questions and answers to reinforce content and learnings. Chapters describing newborn transition, the ACoRN process, supportive care, and safe transport round out the systems-based core. This book is written for any health professional who may be required to participate in the stabilization of sick or preterm babies within their scope of practice.
ISBN
9780197525227
Language
English
Material Type
Book
Call Number
REF EB 800 ACO 2021

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Adolescent health care: A practical guide

https://cwslc.andornot.com/en/permalink/catalog112707
Neinstein, Lawrence S., Gordon, Catherine M., Katzman, Debra K., Rosen, David S., Woods, Elizabeth R. Philadelphia, PA: Lippincott Williams & Wilkins , 2008. 5th ed.
Material Type
Book
Call Number
REF GL 200 NEI 2008
Availability
1 copy, 1 available
Deals with adolescent medicine. This guide is suitable for health care facilities that treat adolescents. Recommended by the American College of Physicians for their internal medicine library, it includes chapters that cover psychosomatic illness and complementary medicine. It can also be used for …
Author
Neinstein, Lawrence S.
Gordon, Catherine M.
Katzman, Debra K.
Rosen, David S.
Woods, Elizabeth R.
Edition
5th ed.
Place of Publication
Philadelphia, PA
Publisher
Lippincott Williams & Wilkins
Publication Date
2008
Physical Description
Hardcover: 1132 P.
Subject
Young Adults
Young Adults Health Promotion
Young Adults Sexuality
Sexual Health
Young Adults Coping with Family Illness
Young Adults-Mental Health. Psychology
Abstract
Deals with adolescent medicine. This guide is suitable for health care facilities that treat adolescents. Recommended by the American College of Physicians for their internal medicine library, it includes chapters that cover psychosomatic illness and complementary medicine. It can also be used for board preparation.
ISBN
9780781792561
Language
English
Material Type
Book
Call Number
REF GL 200 NEI 2008

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Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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American journal of human genetics

https://cwslc.andornot.com/en/permalink/catalog114382

Anti-racist health care practice

https://cwslc.andornot.com/en/permalink/catalog114282
McGibbon, Elizabeth Anne, Etowa, Josephine B.;. [Toronto, ON]: Canadian Scholars Press , 2009.
Material Type
Book
Call Number
REF BE 500 MCG 2009
Availability
1 copy, 1 available
Building on an everyday clinical practice perspective, the authors provide clear and detailed definitions of concepts and terms related to racism and health. Filled with examples of racism in the health care system and strategies to examine and contest racism, this book will become an essential res…
Author
McGibbon, Elizabeth Anne
Etowa, Josephine B.;
Place of Publication
[Toronto, ON]
Publisher
Canadian Scholars Press
Publication Date
2009
Physical Description
Paperback, 245 p., ill.
Subject
Leadership/Coaching
Public Health and Safety
Bullying
Abstract
Building on an everyday clinical practice perspective, the authors provide clear and detailed definitions of concepts and terms related to racism and health. Filled with examples of racism in the health care system and strategies to examine and contest racism, this book will become an essential resource for students and practitioners in the health sciences, the sociology of health, and a variety of other disciplines which investigate racism.
ISBN
9781551303550
Language
English
Material Type
Book
Call Number
REF BE 500 MCG 2009

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copy 1 BC Children's and Women's Study and Learning Commons Available
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Are you culturally competent?

https://cwslc.andornot.com/en/permalink/catalog111191
Ammerican Academy of Orthopaedic Surgeons (AAOS). Warsaw, IN: Zimmer Inc. , 2005.
Material Type
CD
Audio
Call Number
REF GN 300 CUL 2005
Availability
1 copy, 1 available
The Cultural Competency Challenge is a self-assessment and learning tool, showcasing 18 diverse patient cases, designed to help surgeons become more aware of cultural differences among their patients, including communication and clinical considerations.
Author
Ammerican Academy of Orthopaedic Surgeons (AAOS)
Place of Publication
Warsaw, IN
Publisher
Zimmer Inc.
Publication Date
2005
Physical Description
1 CD-ROM
Subject
Cross-Cultural Health Care
Minority Health
Patient-Health Care Practitioner Relations. Doctor-Patient Relations.
Patient Relations
Abstract
The Cultural Competency Challenge is a self-assessment and learning tool, showcasing 18 diverse patient cases, designed to help surgeons become more aware of cultural differences among their patients, including communication and clinical considerations.
Notes
AAOS Product: #02735
Language
English
Material Type
CD
Audio
Call Number
REF GN 300 CUL 2005

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Assessment of Autism Spectrum Disorder: Critical issues in clinical, forensic, and school settings

https://cwslc.andornot.com/en/permalink/catalog120001
Kroncke, Anna P., Willard, Marcy, Huckabee, Helena. Cham, Switzerland: Springer International Publishing , 2016.
Material Type
Book
Call Number
REF FM 272 KRO 2016
Availability
1 copy, 1 available
This book offers clear best-practice guidelines for the assessment of Autism Spectrum Disorder. It discusses both the rising rates of autism and the growing need for appropriate, effective treatments and services. The book examines measures and methods used in assessing for core symptoms of ASD as …
Author
Kroncke, Anna P.
Willard, Marcy
Huckabee, Helena
Place of Publication
Cham, Switzerland
Publisher
Springer International Publishing
Publication Date
2016
Physical Description
Hardcover; 546 p.
Subject
Autism Spectrum Disorder (includes Asperger Syndrome)
Abstract
This book offers clear best-practice guidelines for the assessment of Autism Spectrum Disorder. It discusses both the rising rates of autism and the growing need for appropriate, effective treatments and services. The book examines measures and methods used in assessing for core symptoms of ASD as well as memory, attention, visual and spatial skills, and other areas relevant to autism assessment. In-depth material on differential diagnosis and a range of comorbid conditions depict the complexities of the assessment process and the necessity of accurate identification. The book's case vignettes and sample recommendations add practical and personal dimensions to issues and challenges surrounding diagnosis.
Topics featured include:
A practical guide to the comprehensive assessment process.
Discussion of the assessment process from referral to recommendation.
Diagnostic framework for ASD and other disorders
School-based ASD eligibility evaluation.
Assessment across the lifespan.
Assessment of Autism Spectrum Disorder is an important tool for clinicians, practitioners, researchers and graduate students in the fields of child and school psychology, behavioral therapy, and social work as well as the related areas of psychiatry, pediatrics, forensic psychology, and educational and healthcare policy.
ISBN
9783319255026
Language
English
Material Type
Book
Call Number
REF FM 272 KRO 2016

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Atlas of human cross-sectional anatomy: With CT and MR images

https://cwslc.andornot.com/en/permalink/catalog112634
Cahill, Donald R., Orland, Matthew J., Miller, Gary M. [Toronto, ON]: Wiley-Liss , 1995. 3rd ed.
Material Type
Book
Call Number
REF AC 205 CAH 1995
Availability
1 copy, 1 available
This atlas provides detailed illustrations of anatomical cross-sections - meticulously drawn and labeled - that are matched with high-quality CT or MR images or actual photographs of cadaver sections. Orientation diagrams appear on the corner of every page and show precisely where the slice was tak…
Author
Cahill, Donald R.
Orland, Matthew J.
Miller, Gary M.
Edition
3rd ed.
Place of Publication
[Toronto, ON]
Publisher
Wiley-Liss
Publication Date
1995
Physical Description
Hardcover: 300 p.
Subject
Anatomy-Atlases. Pictorial Works
Abstract
This atlas provides detailed illustrations of anatomical cross-sections - meticulously drawn and labeled - that are matched with high-quality CT or MR images or actual photographs of cadaver sections. Orientation diagrams appear on the corner of every page and show precisely where the slice was taken as well as the direction from which the slice is being viewed.
ISBN
9780471591658
Language
English
Material Type
Book
Call Number
REF AC 205 CAH 1995

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ATTENDING: Medicine, Mindfulness & Humanity

https://cwslc.andornot.com/en/permalink/catalog124049
Epstein, Ronald. New York: Scribner , 2017.
Material Type
Book
Call Number
REF MD 106 EPS 2017
Availability
1 copy, 0 available
The first book for the general public about the importance of mindfulness in medical practice, Attending is a groundbreaking, intimate exploration of how doctors approach their work with patients. From his early days as a Harvard Medical School student, Epstein saw what made good doctors great?more…
Author
Epstein, Ronald
Place of Publication
New York
Publisher
Scribner
Publication Date
2017
Physical Description
292pp
Subjects
Mind and body
Meditation
Abstract
The first book for the general public about the importance of mindfulness in medical practice, Attending is a groundbreaking, intimate exploration of how doctors approach their work with patients. From his early days as a Harvard Medical School student, Epstein saw what made good doctors great?more accurate diagnoses, fewer errors, and stronger connections with their patients. This made a lasting impression on him and set the stage for his life?s work?identifying the qualities and habits that distinguish master clinicians from those who are merely competent. The secret, he learned, was mindfulness.
ISBN
978-15011-21722
Language
English
Material Type
Book
Call Number
REF MD 106 EPS 2017

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Copy 1 BC Children's and Women's Study and Learning Commons REF On Loan, due Wednesday, June 21, 2023
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Behavioral health care: Assessment, service planning, and total clinical outcomes management

https://cwslc.andornot.com/en/permalink/catalog111044
Lyons, John S., Weiner, Dana A. Kingston, NJ: Civic Research Institute , 2009.
Material Type
Book
Call Number
REF CC 600 LYO 2009
Availability
1 copy, 1 available
This book provides an approach for delivering more effective—and cost effective—behavioral health services. It offeres solutions to help improve the service delivery process, fine-tune behavioral health care needs assessments, match the level of care you provide to patients' needs and…
Author
Lyons, John S.
Weiner, Dana A.
Place of Publication
Kingston, NJ
Publisher
Civic Research Institute
Publication Date
2009
Physical Description
Hardcover: [534] p.
Subject
Behaviour Therapy. Behaviour Modification
Health Care Delivery Systems
Abstract
This book provides an approach for delivering more effective—and cost effective—behavioral health services. It offeres solutions to help improve the service delivery process, fine-tune behavioral health care needs assessments, match the level of care you provide to patients' needs and to retrieve better results.
ISBN
1887554696
Language
English
Material Type
Book
Call Number
REF CC 600 LYO 2009

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Best practice guidelines for mental health disorders in the perinatal period

https://cwslc.andornot.com/en/permalink/catalog112945
BC Reproductive Mental Health Program, Perinatal Services BC. [Vancouver, BC?]: BC Reproductive Mental Health , 2014.
Website
http://www.perinatalservicesbc.ca/Documents/Guidelines-Standards/Maternal/MentalHealthDisordersGuideline.pdf
Material Type
Book
Call Number
REF GH 200 BCR 2014
Availability
1 copy, 1 available
These guidelines are designed to support healthcare clinicians with early detection and treatment of mental health disorders in pregnant and postpartum women.; The guidelines include:; • an overview of mental health disorders in the perinatal period;; • four common disorders: depression, …
  1 image     1 website  
Website
http://www.perinatalservicesbc.ca/Documents/Guidelines-Standards/Maternal/MentalHealthDisordersGuideline.pdf
Corporate Author
BC Reproductive Mental Health Program
Perinatal Services BC
Place of Publication
[Vancouver, BC?]
Publisher
BC Reproductive Mental Health
Publication Date
2014
Physical Description
Softcover: 90 p.
Subject
Pregnancy/Childbirth. Obstetrics
Mental Health/Illness
Prenatal Care
Mental Health
Anxiety
Abstract
These guidelines are designed to support healthcare clinicians with early detection and treatment of mental health disorders in pregnant and postpartum women.
The guidelines include:
• an overview of mental health disorders in the perinatal period;
• four common disorders: depression, anxiety disorders, bipolar disorder, and psychotic disorders, including postpartum psychosis; and
• education and prevention, screening and diagnosis, treatment, and recommendations for each disorder.
Notes
Please note that the version for sale is in BLACK & WHITE only.
Language
English
Material Type
Book
Call Number
REF GH 200 BCR 2014

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Beyond self-care for helping professionals : the expressive therapies continuum and the life enrichment model

https://cwslc.andornot.com/en/permalink/catalog124763
Hinz, Lisa D. New York, NY: Routledge , 2019.
Material Type
Book
Call Number
AA 74 HIN 2019
Availability
2 copies, 2 available
Beyond Self-Care for Helping Professionals is an innovative guide to professional self-care focused not just on avoiding the consequences of failing to take care of oneself, but on optimal health and positive psychology. This new volume builds upon the Expressive Therapies Continuum to introduce th…
  1 image     1 document  
Author
Hinz, Lisa D.
Place of Publication
New York, NY
Publisher
Routledge
Publication Date
2019
Physical Description
134p
Subjects
Self Care
Caregivers
Healthy Lifestyle
Abstract
Beyond Self-Care for Helping Professionals is an innovative guide to professional self-care focused not just on avoiding the consequences of failing to take care of oneself, but on optimal health and positive psychology. This new volume builds upon the Expressive Therapies Continuum to introduce the Life Enrichment Model, a strengths-based model that encourages mindful participation in a broad array of enriching experiences. By enabling therapists and other Helping Professionals to develop a rich emotional, intellectual, and creative foundation to their lives and clinical practices, this guide sets a new standard for self-care in the helping professions.
ISBN
9781138231016
Language
English
Material Type
Book
Call Number
AA 74 HIN 2019

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Documents

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Biomedical informatics: Computer applications in health care and biomedicine

https://cwslc.andornot.com/en/permalink/catalog113336
Shortliffe, Edward (ed.), Cimino, James (ed.). London, UK: Springer , 2014. 4th ed.
Material Type
Book
Call Number
REF AA 150 SHO 2014
Availability
1 copy, 1 available
This text provides comprehensive introduction to key topics in the field and the underlying scientific issues that sit at the intersection of biomedical science, patient care, public health, and information technology (IT). Emphasizing the conceptual basis of the field rather than technical details…
Author
Shortliffe, Edward (ed.)
Cimino, James (ed.)
Edition
4th ed.
Place of Publication
London, UK
Publisher
Springer
Publication Date
2014
Physical Description
xxvi, 965 p. : ill., port.
Subject
Health Informatics
Abstract
This text provides comprehensive introduction to key topics in the field and the underlying scientific issues that sit at the intersection of biomedical science, patient care, public health, and information technology (IT). Emphasizing the conceptual basis of the field rather than technical details, it provides an introduction and extensive bibliography so that readers can comprehend, assess, and utilize biomedical informatics and health IT. The volume focuses on easy-to-understand examples, a guide to additional literature, chapter summaries, and a comprehensive glossary with concise definitions of recurring terms for self-study or classroom use.
ISBN
9781447144731
Language
English
Material Type
Book
Call Number
REF AA 150 SHO 2014

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Business of kindness: Creating work environments where people thrive

https://cwslc.andornot.com/en/permalink/catalog109719
McIvor, Olivia. Lions Bay, BC: Fairwinds Press , 2006.
Material Type
Book
Call Number
REF BD 620 MCI 2006
Availability
1 copy, 1 available
The Business of Kindness™ is a leading-edge approach aimed at enhancing wellness and sustainability for employees throughout the organization as well as for the organization itself.
Author
McIvor, Olivia
Place of Publication
Lions Bay, BC
Publisher
Fairwinds Press
Publication Date
2006
Physical Description
Paperback, 241 p.
Subject
Work Behaviour
Job Satisfaction
Abstract
The Business of Kindness™ is a leading-edge approach aimed at enhancing wellness and sustainability for employees throughout the organization as well as for the organization itself.
ISBN
0968214991
Language
English
Material Type
Book
Call Number
REF BD 620 MCI 2006

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Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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Cardiovascular, metabolic, endocrine and behavioral aspects of development in postnatal lambs in relation to age, sex, lamb number and acute fluoxetine administration

https://cwslc.andornot.com/en/permalink/catalog113943
Nguyen, Tuan-Anh Thi. [Vancouver, BC?]: University of British Columbia , 2013.
Website
http://hdl.handle.net/2429/44653
Material Type
Thesis
Call Number
Thesis Shelf
Human newborns exposed in utero to maternally administered SSRIs such as fluoxetine (FX) have an increased risk of adverse pregnancy outcomes including poor neonatal adaptation. This comprises respiratory difficulty, jitteriness, cyanosis when feeding and persists for several days after birth. Seve…
Website
http://hdl.handle.net/2429/44653
Author
Nguyen, Tuan-Anh Thi
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2013
Subject
Faculty of Medicine
Theses
Abstract
Human newborns exposed in utero to maternally administered SSRIs such as fluoxetine (FX) have an increased risk of adverse pregnancy outcomes including poor neonatal adaptation. This comprises respiratory difficulty, jitteriness, cyanosis when feeding and persists for several days after birth. Several potential mechanisms underlying these symptoms have been proposed: 1) acute toxicity to the drugs (i.e. serotonin syndrome), 2) withdrawal syndrome due to the sudden discontinuation of maternal-fetal placental drug transfer at birth or 3) an SSRIs-elicited alteration in fetal brain development. However, the actual mechanism has not been elucidated.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Care of the high-risk neonate

https://cwslc.andornot.com/en/permalink/catalog112665
Fanaroff, Avroy A., Fanaroff, Jonathan M. Philadelphia, PA: Elsevier Saunders , 2013. 6th Ed.
Material Type
Book
Call Number
REF EB 800 FAN 2013
Availability
1 copy, 0 available
This neonatology reference thoroughly covers the new guidelines, equipment, drugs, and treatments that have greatly increased the chance of survival for high-risk infants. Expert contributors deliver the information you need to stay on top of the technological and medical advances in this challengi…
Author
Fanaroff, Avroy A.
Fanaroff, Jonathan M.
Edition
6th Ed.
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Publication Date
2013
Physical Description
Hardcover, 626 pages
Subject
Infants
Infants (Newborn)-Diseases
Neonatal Assessment
UBC MD Undergrad
Abstract
This neonatology reference thoroughly covers the new guidelines, equipment, drugs, and treatments that have greatly increased the chance of survival for high-risk infants. Expert contributors deliver the information you need to stay on top of the technological and medical advances in this challenging field.
ISBN
978-1-4160-4001-9
Language
English
Material Type
Book
Call Number
REF EB 800 FAN 2013

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF On Loan, due Wednesday, December 11, 2019
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Caring for women with problematic substance use, their newborns & families: A self-directed learning module

https://cwslc.andornot.com/en/permalink/catalog109530
Seymour, Laurie, Payne, Sarah, BC Women's Hospital & Health Centre. [Vancouver, BC?]: BC Women's Hospital + Health Centre , 2006.
Material Type
Book
Call Number
REF DB 100 CAR 2006
Availability
1 copy, 1 available
This self-directed learning module is designed to assist nurses in developing their competency in working with childbearing women with problematic substance use and their newborns.
Author
Seymour, Laurie
Payne, Sarah
BC Women's Hospital & Health Centre
Place of Publication
[Vancouver, BC?]
Publisher
BC Women's Hospital + Health Centre
Publication Date
2006
Physical Description
Spiral bound paperback: 156 pages
Subject
Substance Use
Substance Abuse
Women's Health. Gynecology
Abstract
This self-directed learning module is designed to assist nurses in developing their competency in working with childbearing women with problematic substance use and their newborns.
Language
English
Material Type
Book
Call Number
REF DB 100 CAR 2006

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Challenging genetic determinism: New perspectives on the gene in its multiple environments

https://cwslc.andornot.com/en/permalink/catalog113270
Maheu, Louis, Macdonal, Roderick A. (Eds). Kingston, ON: McGill-Queen's University Press , 2011.
Material Type
Book
Call Number
REF GI 200 MAC 2011
Availability
2 copies, 2 available
Advances in genetic research have captured the attention of the media and the public through reports about genetically caused diseases and behaviours. However, all too often the coverage of scientists' innovations has implied that genetic factors alone are responsible for effects ranging from perso…
Author
Maheu, Louis
Macdonal, Roderick A. (Eds)
Place of Publication
Kingston, ON
Publisher
McGill-Queen's University Press
Publication Date
2011
Physical Description
319 pages
Subject
Personality
Genetics
UBC MD Undergrad
Abstract
Advances in genetic research have captured the attention of the media and the public through reports about genetically caused diseases and behaviours. However, all too often the coverage of scientists' innovations has implied that genetic factors alone are responsible for effects ranging from personality and sexual preferences to morbid obesity and intellectual disabilities. Challenging Genetic Determinism argues that hypotheses cannot be based solely on genetic factors but must take into account the context in which these factors occur.
ISBN
978-0773538139
Language
English
Material Type
Book
Call Number
REF GI 200 MAC 2011

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Copy 2 BC Children's and Women's Study and Learning Commons REF Available
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The characterization of ADAMTS-12 in the regulation of human trophoblast invasion in vitro

https://cwslc.andornot.com/en/permalink/catalog113949
Zou, Junxuan. [Vancouver, BC?]: University of British Columbia , 2010.
Website
http://hdl.handle.net/2429/29783
Material Type
Thesis
Call Number
Thesis Shelf
The distintegrin-like and metalloproteinase with thrombospondin repeats (ADAMTS) are members of a gene family of secreted, multidomain and multifunctional proteinases that are able to proteolytically degrade a diverse array of cellular, extracellular and extracellular matrix (ECM) substrates. We ex…
Website
http://hdl.handle.net/2429/29783
Author
Zou, Junxuan
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2010
Subject
Faculty of Medicine
Theses
Abstract
The distintegrin-like and metalloproteinase with thrombospondin repeats (ADAMTS) are members of a gene family of secreted, multidomain and multifunctional proteinases that are able to proteolytically degrade a diverse array of cellular, extracellular and extracellular matrix (ECM) substrates. We examined the presence of ADAMTS in first trimester human placenta and only ADAMTS-12 was present in cultures of invasive extravillous cytotrophoblast (EVT) at significantly higher levels than in poorly invasive JEG-3 chorocarcinoma cells. Immunohistochemistry staining of chorionic villi derived from first trimester human placenta demonstrated that ADAMTS-12 was intensively immunolocalized in the cytotrophoblast layer but weakly immunolocalized in the poorly-invasive syncytial trophoblast layer.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Characterization of the human gonadotropin-releasing hormone receptor gene at the molecular level

https://cwslc.andornot.com/en/permalink/catalog113982
Fan, Nancy C. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7255
Material Type
Thesis
Call Number
Thesis Shelf
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling sti…
Website
http://hdl.handle.net/2429/7255
Author
Fan, Nancy C.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling stimulates the synthesis and release of both luteinizing hormone and follicle stimulating hormone from the anterior pituitary. In addition, GnRH - GnRH receptor binding acts locally to regulate human chorionic gonadotropin secretion in the placenta and steroidogenesis in the ovary. The objective of this thesis was to isolate and characterize the gene for the GnRH receptor in human.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
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