name:"Wu, Elizabeth Xianshi" found 1 record

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X-chromosome inactivation and FMR1 CGG repeat and AGG interspersion number in female newborns conceived by assisted reproductive technologies (ARTs)

https://cwslc.andornot.com/en/permalink/catalog113945

Wu, Elizabeth Xianshi. [Vancouver, BC?]: University of British Columbia , 2012.

Website: http://hdl.handle.net/2429/42609

Material Type: Thesis

Call Number: Thesis Shelf

Pregnancies derived from in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are associated with increased rates of chromosome abnormalities, congenital malformations, low birth weight, pre-term births, multiple gestations, and imprinting disorders. Assisted reproductive techno…

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Website: http://hdl.handle.net/2429/42609

Author: Wu, Elizabeth Xianshi

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 2012

Subject: Faculty of Medicine; Theses

Abstract: Pregnancies derived from in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are associated with increased rates of chromosome abnormalities, congenital malformations, low birth weight, pre-term births, multiple gestations, and imprinting disorders. Assisted reproductive technologies (ARTs) enable sub-fertile individuals to circumvent the natural selective pressures involved in human reproduction. The risks of ARTs may be due to the underlying causes of subfertility in these individuals or to the artificial processes used to achieve pregnancy. X-chromosome inactivation (XCI) may be at risk to perturbations in ARTs as it is thought to occur during the blastocyst stage when in vitro culturing would be taking place. We examined the XCI status in females conceived by ICSI (n=70), IVF (n=68), and naturally (NC, n=42).

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

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http://hdl.handle.net/2429/42609