Website

http://hdl.handle.net/2429/33832

Author

Chan Wong, Edgar Antonio

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2011

Subject

Faculty of Medicine

Theses

Abstract

In-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are two of the most common forms of assisted reproductive technologies (ARTs) used to treat human infertility. Presently, over two million children have been conceived by ART. The majority of these children are born healthy. However, IVF and ICSI have been associated with increased risks of adverse perinatal health outcomes. The higher risk of low birth weight, intrauterine growth restriction, and small for gestational age are of special concern due to its association with adult-onset diseases. In this thesis project, the effect of ART on the genetic and epigenetic status of the placenta, and their associations with fetal growth restriction are examined.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Copies

Website

http://hdl.handle.net/2429/16403

Author

Devarakonda, Rajashree M.

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2005

Subject

Faculty of Medicine

Theses

Abstract

Pre-eclampsia (PET) continues to contribute to maternal and perinatal morbidity and mortality. Management decisions include an evaluation of maternal risk, which is assisted by expert opinion-based guidelines, while not accounting for gestational age (GA) at diagnosis. We evaluated the feasibility of developing a severity score that can predict adverse maternal outcome.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf