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2 records – page 1 of 1.

Characterization of the human gonadotropin-releasing hormone receptor gene at the molecular level

https://cwslc.andornot.com/en/permalink/catalog113982
Fan, Nancy C. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7255
Material Type
Thesis
Call Number
Thesis Shelf
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling sti…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/7255
Author
Fan, Nancy C.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling stimulates the synthesis and release of both luteinizing hormone and follicle stimulating hormone from the anterior pituitary. In addition, GnRH - GnRH receptor binding acts locally to regulate human chorionic gonadotropin secretion in the placenta and steroidogenesis in the ovary. The objective of this thesis was to isolate and characterize the gene for the GnRH receptor in human.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/7255
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The maternal predisposition to the syndrome of pre-eclampsia

https://cwslc.andornot.com/en/permalink/catalog113968
Alasaly, Kadria A. [Vancouver, BC?]: University of British Columbia , 2004.
Website
http://hdl.handle.net/2429/15429
Material Type
Thesis
Call Number
Thesis Shelf
Pre-eclampsia, which is characterized by maternal hypertension, proteinuria, hypoperfusion of end organs and a systemic maternal innate inflammatory response, is a leading cause of maternal mortality and morbidity world-wide. When of early-onset, pre-eclampsia is associated with fetal intrauterine …
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/15429
Author
Alasaly, Kadria A.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2004
Subject
Faculty of Medicine
Theses
Abstract
Pre-eclampsia, which is characterized by maternal hypertension, proteinuria, hypoperfusion of end organs and a systemic maternal innate inflammatory response, is a leading cause of maternal mortality and morbidity world-wide. When of early-onset, pre-eclampsia is associated with fetal intrauterine growth restriction (IUGR). IUGR can occur in isolation, so-called normotensive IUGR. What is poorly understood is that some women develop the maternal syndrome of pre-eclampsia whilst others have only the fetal syndrome (normotensive IUGR), despite the fact that the initiating event in both is believed to be reduced uteroplacental perfusion.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/15429
Show Less