Website

http://hdl.handle.net/2429/1228

Author

Ferguson, Kyle Akira

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2008

Subject

Faculty of Medicine

Theses

Abstract

While the introduction of intracytoplasmic sperm injection (ICSI) has revolutionized the treatment of male infertility, concerns have been raised regarding the risk of chromosomal abnormalities in pregnancies derived from ICSI. Studies on sperm from infertile men have suggested that this population may produce higher rates of aneuploid sperm. Thus, we hypothesized that defects in early meiotic events may contribute to both male infertility and the production of aneuploid sperm.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

http://hdl.handle.net/2429/9705

Author

Kirkpatrick, Gordon

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2009

Subject

Faculty of Medicine

Theses

Abstract

Male carriers of chromosomal abnormalities (CA) are more frequent in the infertile population. These men have higher levels of sperm aneuploidy due to the aberrant segregation of the chromosomes involved in the abnormality. The presence of a CA may also influence the segregation of other chromosomes, in a process known as in interchromosomal effect (ICE). The behaviour of the CA during meiosis may account for the infertility observed in this population. We studied chromosome segregation, ICE and meiotic defects in a variety of CA. In carriers of CA, we determined the segregation patterns of chromosomes involved in the abnormality.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

http://www.longwoods.com/home.php?cat=571

Website Notes

To read individual chapters online...click on the link above

Author

Baker, G. Ross

MacIntosh-Murray, Anu

Porcellato, Christina

Dionne, Lynn

Stelmacovich, Kim

Born, Karen

Place of Publication

[Toronto, ON]

Publisher

Longwoods Publishing Corporation

Publication Date

2008

Physical Description

Paperback: 292 pages.

Subject

Health Care Delivery Systems

Hospitals Services

Abstract

An examination of leadership strategies, organizational processes and investments made to create and sustain improvement in healthcare.

ISBN

9780981008905

Language

English

Material Type

Book

Call Number

REF JB 100 BAK 2008

Copies

Website

http://www.nap.edu/catalog.php?record_id=11903

Website Notes

Read online or download as PDF.

Author

Olsen, LeighAnne;

Aisner, Dara;

McGinnis, J. Michael (Eds).

Place of Publication

Washington, DC

Publisher

National Academies Press

Publication Date

2007

Physical Description

374 pages, 2 MB PDF file.

Subject

Health Care Delivery Systems

Evidence-Based Medicine

Abstract

This book considers how health care is structured to develop and to apply evidence--from health profession training and infrastructure development to advances in research methodology, patient engagement, payment schemes, and measurement--and highlights opportunities for the creation of a sustainable learning health care system that gets the right care to people when they need it and then captures the results for improvement. This book will be of primary interest to hospital and insurance industry administrators, health care providers, those who train and educate health workers, researchers, and policymakers.

ISBN

978-0-309-10300-8

Language

English

Material Type

Online