Publisher

ThedaCare Center for Healthcare Value

Publication Date

2011

Physical Description

DVD

Subject

Lean Leader Development

Abstract

In this DVD, you will see ThedaCare's leading lean practices at their system-level boardroom (the "visual room") and at multiple locations throughout Appleton Medical Center. You will hear directly from the leading figures in the development of the ThedaCare Improvement System: Dr. John Toussaint, CEO of the ThedaCare Center for Healthcare Value, and Dr. Dean Gruner, CEO of ThedaCare. You will also see and hear other leaders, from the hospital COO to a unit-level nursing manager, describe how strategy deployment creates alignment throughout the organization.

The DVD illustrates how ThedaCare's "true north" objectives are translated to multiple departments. You will also see how leaders use standardized visual boards to track key metrics, rapid improvement events, and staff suggestions - all aimed at providing the best patient care.

Language

English

Material Type

Video

Call Number

REF AA 120 THE 2011

Copies

Website

http://hdl.handle.net/2429/35861

Author

Hong, Eui-ju

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2011

Subject

Faculty of Medicine

Theses

Abstract

Sex hormone-binding globulin (SHBG) binds androgens and estrogens with high affinity, and regulates the distribution of these sex steroids in the blood and other biological fluids. Liver is the primary site of SHBG production, but the human SHBG transcription unit responsible for this is also expressed in proximal convoluted tubule (PCT) epithelial cells in a transgenic mouse model. Unlike hepatocytes which actively secrete SHBG and retain little immunoreactive SHBG within their cytoplasm, an incompletely glycosylated SHBG isoform has been found to accumulate inside PCT cells. These cells are androgen target cells, and the presence of SHBG within them accentuates androgen-dependent regulation of gene expression mediated by the androgen receptor (AR).

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

http://hdl.handle.net/2429/29313

Author

Wang, Jian

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

1989

Subject

Faculty of Medicine

Theses

Abstract

The present study was conducted to investigate the hypothesis that membrane phosphoinositide breakdown may participate in the actions of luteinizing hormone-releasing hormone (LHRH) on hormone production in the rat ovary. In granulosa cells prelabeled with [³H]-arachidonic acid or [³H]-inositol, treatment with LHRH increased the accumulation of radiolabeled inositol lipids, diacylglycerol and free arachidonic acid, but luteinizing hormone (LH) or cholera toxin did not exert the same effect. Activation of protein kinase C by the phorbol ester, 12-0-tetradecanoyl phorbol-13-acetate (TPA) had a stimulatory action on membrane phosphoinositide breakdown.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

http://hdl.handle.net/2429/1395

Author

Nguyen, Tuan-Anh T

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2008

Subject

Faculty of Medicine

Theses

Abstract

Due to the ?flare effect? associated with the flare protocol, variation in the degree of follicular maturation during stimulation may result in differences in follicle response as compared to the luteal protocol which is based on maximal pituitary suppression and synchronization of follicular maturation. In this study, besides other methods, Anti-Mullerian Hormone (AMH), a novel marker for ovarian reserve, was used as a tool to evaluate the ovarian responsiveness to stimulation.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf