Skip header and navigation
C&W Library Catalogue

Browse and borrow resources that support the learning needs and professional development of C&W staff, clinicians, students and faculty.

Revise Search

1 records – page 1 of 1.

Action of luteinizing hormone-releasing hormone in rat ovarian cells : hormone production and signal transduction

https://cwslc.andornot.com/en/permalink/catalog113996
Wang, Jian. [Vancouver, BC?]: University of British Columbia , 1989.
Website
http://hdl.handle.net/2429/29313
Material Type
Thesis
Call Number
Thesis Shelf
The present study was conducted to investigate the hypothesis that membrane phosphoinositide breakdown may participate in the actions of luteinizing hormone-releasing hormone (LHRH) on hormone production in the rat ovary. In granulosa cells prelabeled with [³H]-arachidonic acid or [³H]-inositol, tr…
Website
http://hdl.handle.net/2429/29313
Author
Wang, Jian
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1989
Subject
Faculty of Medicine
Theses
Abstract
The present study was conducted to investigate the hypothesis that membrane phosphoinositide breakdown may participate in the actions of luteinizing hormone-releasing hormone (LHRH) on hormone production in the rat ovary. In granulosa cells prelabeled with [³H]-arachidonic acid or [³H]-inositol, treatment with LHRH increased the accumulation of radiolabeled inositol lipids, diacylglycerol and free arachidonic acid, but luteinizing hormone (LH) or cholera toxin did not exert the same effect. Activation of protein kinase C by the phorbol ester, 12-0-tetradecanoyl phorbol-13-acetate (TPA) had a stimulatory action on membrane phosphoinositide breakdown.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less