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20 records – page 1 of 1.

Learning healthcare system: Workshop summary (IOM Roundtable on Evidence-Based Medicine)

https://cwslc.andornot.com/en/permalink/catalog113231
Olsen, LeighAnne;, Aisner, Dara;, McGinnis, J. Michael (Eds). Washington, DC: National Academies Press , 2007.
Website
http://www.nap.edu/catalog.php?record_id=11903
Material Type
Online
This book considers how health care is structured to develop and to apply evidence--from health profession training and infrastructure development to advances in research methodology, patient engagement, payment schemes, and measurement--and highlights opportunities for the creation of a sustainabl…
Website
http://www.nap.edu/catalog.php?record_id=11903
Website Notes
Read online or download as PDF.
Author
Olsen, LeighAnne;
Aisner, Dara;
McGinnis, J. Michael (Eds).
Place of Publication
Washington, DC
Publisher
National Academies Press
Publication Date
2007
Physical Description
374 pages, 2 MB PDF file.
Subject
Health Care Delivery Systems
Evidence-Based Medicine
Abstract
This book considers how health care is structured to develop and to apply evidence--from health profession training and infrastructure development to advances in research methodology, patient engagement, payment schemes, and measurement--and highlights opportunities for the creation of a sustainable learning health care system that gets the right care to people when they need it and then captures the results for improvement. This book will be of primary interest to hospital and insurance industry administrators, health care providers, those who train and educate health workers, researchers, and policymakers.
ISBN
978-0-309-10300-8
Language
English
Material Type
Online
Websites
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Communicating risks and benefits: An evidence-based user's guide

https://cwslc.andornot.com/en/permalink/catalog111871
Fischhoff, Baruch, Brewer, Noel T., Downs, Julie S.(eds.). Maryland, USA: FDA, US Department of Health & Human Services , 2011.
Website
http://www.cw.bc.ca/library/pdf/Risk communication book remediated2.pdf
Material Type
Book
Online
Effective risk communication is essential to the well-being of any organization and those people who depend on it. Ineffective communication can cost lives, money, and reputations. Communicating Risks and Benefits: An Evidence-Based User's Guide provides the scientific foundations for effective …
Website
http://www.cw.bc.ca/library/pdf/Risk communication book remediated2.pdf
Website Notes
Click on the link above to view/print.
Author
Fischhoff, Baruch
Brewer, Noel T.
Downs, Julie S.(eds.)
Corporate Author
Food & Drug Administration (FDA), US Department of Health & Human Services
Place of Publication
Maryland, USA
Publisher
FDA, US Department of Health & Human Services
Publication Date
2011
Physical Description
PDF file: 242 p.
Subject
Leadership/Coaching
Communication
Abstract
Effective risk communication is essential to the well-being of any organization and those people who depend on it. Ineffective communication can cost lives, money, and reputations. Communicating Risks and Benefits: An Evidence-Based User's Guide provides the scientific foundations for effective communication.
Language
English
Material Type
Book
Online
Websites
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Clinical and endocrine responses to ovarian hyperstimulation in flare and and luteal gonadotropin-releasing hormone agonist (GnRHa) protocols

https://cwslc.andornot.com/en/permalink/catalog113958
Nguyen, Tuan-Anh T. [Vancouver, BC?]: University of British Columbia , 2008.
Website
http://hdl.handle.net/2429/1395
Material Type
Thesis
Call Number
Thesis Shelf
Due to the ?flare effect? associated with the flare protocol, variation in the degree of follicular maturation during stimulation may result in differences in follicle response as compared to the luteal protocol which is based on maximal pituitary suppression and synchronization of follicular matur…
Website
http://hdl.handle.net/2429/1395
Author
Nguyen, Tuan-Anh T
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2008
Subject
Faculty of Medicine
Theses
Abstract
Due to the ?flare effect? associated with the flare protocol, variation in the degree of follicular maturation during stimulation may result in differences in follicle response as compared to the luteal protocol which is based on maximal pituitary suppression and synchronization of follicular maturation. In this study, besides other methods, Anti-Mullerian Hormone (AMH), a novel marker for ovarian reserve, was used as a tool to evaluate the ovarian responsiveness to stimulation.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Chinese cancer patient peer navigator toolkit: A model for language-based peer navigation

https://cwslc.andornot.com/en/permalink/catalog112530
Kwong, Sandy. [Vancouver, BC?]: BC Cancer Agency , 2013.
Website
http://www.cw.bc.ca/library/pdf/2013PeerNavigatorToolkit.pdf
Material Type
Book
Call Number
REF FE 220 CHI 2013
Availability
1 copy, 1 available
This guide describes the principles and processes involved in the development of the Chinese Peer Navigator Program at the BC Cancer Agency, Vancouver Centre and the bilingual resources that are used with Chinese-speaking patients (Mandarin, Cantonese and English).; This program also reflects “be…
  1 image     1 website  
Website
http://www.cw.bc.ca/library/pdf/2013PeerNavigatorToolkit.pdf
Author
Kwong, Sandy
Place of Publication
[Vancouver, BC?]
Publisher
BC Cancer Agency
Publication Date
2013
Physical Description
Softcover: 27 p.
Subject
Cancer-Coping
Cancer
Abstract
This guide describes the principles and processes involved in the development of the Chinese Peer Navigator Program at the BC Cancer Agency, Vancouver Centre and the bilingual resources that are used with Chinese-speaking patients (Mandarin, Cantonese and English).
This program also reflects “best practice” standards and can be used for future groups or organizations who may wish to adapt it for future peer navigator programs.
Language
English
Chinese
Material Type
Book
Call Number
REF FE 220 CHI 2013

Copies

Copy 1 BC Children's and Women's Study and Learning Commons Available
Images
Websites
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Journal of Clinical Investigation

https://cwslc.andornot.com/en/permalink/catalog119694
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp39613&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=Journal+of+Clinical+Investigation
Alternate Title
JCI
Place of Publication
Ann Arbor, MI
Publisher
American Society for Clinical Investigation
Publication Date
1924 - present
ISSN
0021-9738
Language
English
Material Type
Serial
Frequency
Monthly
Holdings
CFRI/Study & Learning Commons - Print: v.93:1-v.122:3 (1994-2012); v.124:1 (2014).
Missing: v.95:1 (1995); v.98:12 (1996); v.99:7-12 (1997); v.101:5 (1998); v.104:2 (1999); v.107:3, v.108:9 (2001); v.109:1,6,7 (2002); v.113:1,8,10,11; v.114:4,6,11 (2004); v.115:1,7-9 (2005); v.116:1,3,5,12 (2006); v.117:7,10 (2007); v.118:8 (2008).
Online: 1924 to present.
Websites
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American journal of clinical nutrition

https://cwslc.andornot.com/en/permalink/catalog114381

Clinical and investigative medicine (CIM). Médicine Clinique et Expérimentale: Official Journal of the Canadian Society for Clinical Investigation.

https://cwslc.andornot.com/en/permalink/catalog114753
Website
PHSA Users:
http://web.b.ebscohost.com/pfi/detail/detail?sid=8eead011-1960-4015-b7da-0e70b0435dd6%40sessionmgr105&vid=0&hid=118&bdata=JnNpdGU9cGZpLWxpdmU%3d#AN=edp18037&db=edspub
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=clinical+and+investigative+medicine
Place of Publication
[Ottawa, ON]
Publisher
Canadian Society for Clinical Investigation (CSCI)
Publication Date
1978 - Present
Notes
Print issues ceased with v. 29, no. 5 (Dec. 2006)
Articles in English; summaries in English and French
ISSN
0147-958X
Language
English
Material Type
Serial
Frequency
Bimonthly
Holdings
CFRI/Study & Learning Commons - Print: v.17:1-v.29:6+suppls.
Missing: v.19:3 (1996); v.24:5 (2001).
Online: 1996 to present.
Websites
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Best practice guidelines for mental health disorders in the perinatal period

https://cwslc.andornot.com/en/permalink/catalog112945
BC Reproductive Mental Health Program, Perinatal Services BC. [Vancouver, BC?]: BC Reproductive Mental Health , 2014.
Website
http://www.perinatalservicesbc.ca/Documents/Guidelines-Standards/Maternal/MentalHealthDisordersGuideline.pdf
Material Type
Book
Call Number
REF GH 200 BCR 2014
Availability
1 copy, 1 available
These guidelines are designed to support healthcare clinicians with early detection and treatment of mental health disorders in pregnant and postpartum women.; The guidelines include:; • an overview of mental health disorders in the perinatal period;; • four common disorders: depression, …
  1 image     1 website  
Website
http://www.perinatalservicesbc.ca/Documents/Guidelines-Standards/Maternal/MentalHealthDisordersGuideline.pdf
Corporate Author
BC Reproductive Mental Health Program
Perinatal Services BC
Place of Publication
[Vancouver, BC?]
Publisher
BC Reproductive Mental Health
Publication Date
2014
Physical Description
Softcover: 90 p.
Subject
Pregnancy/Childbirth. Obstetrics
Mental Health/Illness
Prenatal Care
Mental Health
Anxiety
Abstract
These guidelines are designed to support healthcare clinicians with early detection and treatment of mental health disorders in pregnant and postpartum women.
The guidelines include:
• an overview of mental health disorders in the perinatal period;
• four common disorders: depression, anxiety disorders, bipolar disorder, and psychotic disorders, including postpartum psychosis; and
• education and prevention, screening and diagnosis, treatment, and recommendations for each disorder.
Notes
Please note that the version for sale is in BLACK & WHITE only.
Language
English
Material Type
Book
Call Number
REF GH 200 BCR 2014

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
Images
Websites
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Clinical Genetics: An International Journal of Genetics, Molecular and Personalized Medicine

https://cwslc.andornot.com/en/permalink/catalog114754
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp18084&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=clinical+genetics
Place of Publication
Malden, Ma.
Publisher
John Wiley & Sons, Inc.
Publication Date
1970 - Present.
ISSN
0009-9163
Language
English
Material Type
Serial
Frequency
Monthly
Holdings
CFRI/Study & Learning Commons - Print: v.45:6-v.57:4+special issue (1994-2000); v.61:1 (2002); v.69:3-v.76:3 (2006-2009).
Missing: v.51:3, v.52:4 (1997); v.53:2 (1998); v.55:4, v.56:1,3 (1999); v.57:1-3, v.58:1-6 (2000); v.59:1-6, v.60:1-6 (2001); v.61:2-6, v.62:1-6 (2002); 2003-2005; v.69:1-2 (2006); v.73:3-5 (2008); v.75:1,3,4, v.76:2,4-6 (2009).
Online: 1970 to present.
Websites
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Amyloid: the international journal of experimental and clinical investigation: the official journal of the International Society of Amyloidosis

https://cwslc.andornot.com/en/permalink/catalog114439

Amyloid: The International Journal of Experimental & Clinical Investigation: the official journal of the International Society of Amyloidosis

https://cwslc.andornot.com/en/permalink/catalog119862
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp123865&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=I_M&C=1350-6129
Continues / Continued By
Amyloid: The Journal of Protein Folding Disorders
Alternate Title
Amyloid
Place of Publication
Rochester, Mn.
Publisher
The International Society of Amyloidosis
Publication Date
1994 ? Present
ISSN
1350-612
Language
English
Material Type
Serial
Frequency
Irregular or Other
Holdings
CFRI/Study & Learning Commons - Print: v.5:1-v.8:4 +suppls. (1998-2001).
Online: 2003 to present.
Websites
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Profiling the vaginal microbiome in HIV-positive women

https://cwslc.andornot.com/en/permalink/catalog113942
Mahal, Daljeet Singh. [Vancouver, BC?]: University of British Columbia , 2013.
Website
http://hdl.handle.net/2429/44267
Material Type
Thesis
Call Number
Thesis Shelf
Disruptions or imbalances of the vaginal microbiome can lead to negative reproductive health consequences for women, including an increased risk of sexually transmitted infections, pelvic inflammatory disease, and preterm birth. HIV-positive women may be particularly vulnerable to microbiome disrup…
Website
http://hdl.handle.net/2429/44267
Author
Mahal, Daljeet Singh
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2013
Subject
Faculty of Medicine
Theses
Abstract
Disruptions or imbalances of the vaginal microbiome can lead to negative reproductive health consequences for women, including an increased risk of sexually transmitted infections, pelvic inflammatory disease, and preterm birth. HIV-positive women may be particularly vulnerable to microbiome disruptions due to the immune dysfunction intrinsic to this disease. The objective of this study was to explore the vaginal microbiome in HIV-positive reproductive-aged women utilizing cpn60 metagenomic profiling and to correlate vaginal bacterial profiles with demographic/clinical variables.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Cardiovascular, metabolic, endocrine and behavioral aspects of development in postnatal lambs in relation to age, sex, lamb number and acute fluoxetine administration

https://cwslc.andornot.com/en/permalink/catalog113943
Nguyen, Tuan-Anh Thi. [Vancouver, BC?]: University of British Columbia , 2013.
Website
http://hdl.handle.net/2429/44653
Material Type
Thesis
Call Number
Thesis Shelf
Human newborns exposed in utero to maternally administered SSRIs such as fluoxetine (FX) have an increased risk of adverse pregnancy outcomes including poor neonatal adaptation. This comprises respiratory difficulty, jitteriness, cyanosis when feeding and persists for several days after birth. Seve…
Website
http://hdl.handle.net/2429/44653
Author
Nguyen, Tuan-Anh Thi
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2013
Subject
Faculty of Medicine
Theses
Abstract
Human newborns exposed in utero to maternally administered SSRIs such as fluoxetine (FX) have an increased risk of adverse pregnancy outcomes including poor neonatal adaptation. This comprises respiratory difficulty, jitteriness, cyanosis when feeding and persists for several days after birth. Several potential mechanisms underlying these symptoms have been proposed: 1) acute toxicity to the drugs (i.e. serotonin syndrome), 2) withdrawal syndrome due to the sudden discontinuation of maternal-fetal placental drug transfer at birth or 3) an SSRIs-elicited alteration in fetal brain development. However, the actual mechanism has not been elucidated.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Role of receptor tyrosine kinase regulator Sprouty in ovarian cancer cells

https://cwslc.andornot.com/en/permalink/catalog113944
So, Wai Kin. [Vancouver, BC?]: University of British Columbia , 2012.
Website
http://hdl.handle.net/2429/42242
Material Type
Thesis
Call Number
Thesis Shelf
Aberrant epidermal growth factor receptor (EGFR) activity contributes to the development of epithelial ovarian cancer (EOC), a common and lethal female malignancy. Elucidating the regulation of EGFR function will improve treatments for EOC and the survival of patients. This study aims to elucidate …
Website
http://hdl.handle.net/2429/42242
Author
So, Wai Kin
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2012
Subject
Faculty of Medicine
Theses
Abstract
Aberrant epidermal growth factor receptor (EGFR) activity contributes to the development of epithelial ovarian cancer (EOC), a common and lethal female malignancy. Elucidating the regulation of EGFR function will improve treatments for EOC and the survival of patients. This study aims to elucidate the role of Sprouty (SPRY) proteins, which are EGFR regulators, in EOC.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

X-chromosome inactivation and FMR1 CGG repeat and AGG interspersion number in female newborns conceived by assisted reproductive technologies (ARTs)

https://cwslc.andornot.com/en/permalink/catalog113945
Wu, Elizabeth Xianshi. [Vancouver, BC?]: University of British Columbia , 2012.
Website
http://hdl.handle.net/2429/42609
Material Type
Thesis
Call Number
Thesis Shelf
Pregnancies derived from in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are associated with increased rates of chromosome abnormalities, congenital malformations, low birth weight, pre-term births, multiple gestations, and imprinting disorders. Assisted reproductive techno…
Website
http://hdl.handle.net/2429/42609
Author
Wu, Elizabeth Xianshi
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2012
Subject
Faculty of Medicine
Theses
Abstract
Pregnancies derived from in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are associated with increased rates of chromosome abnormalities, congenital malformations, low birth weight, pre-term births, multiple gestations, and imprinting disorders. Assisted reproductive technologies (ARTs) enable sub-fertile individuals to circumvent the natural selective pressures involved in human reproduction. The risks of ARTs may be due to the underlying causes of subfertility in these individuals or to the artificial processes used to achieve pregnancy. X-chromosome inactivation (XCI) may be at risk to perturbations in ARTs as it is thought to occur during the blastocyst stage when in vitro culturing would be taking place. We examined the XCI status in females conceived by ICSI (n=70), IVF (n=68), and naturally (NC, n=42).
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Noninvasive assessment of embryo quality in human in vitro fertilization : metabolomic profiling of embryo culture media with Raman spectroscopy

https://cwslc.andornot.com/en/permalink/catalog113946
Asghari Roodsari, Alaleh. [Vancouver, BC?]: University of British Columbia , 2012.
Website
http://hdl.handle.net/2429/43273
Material Type
Thesis
Call Number
Thesis Shelf
Light microscopy has remained the primary tool for the assessment of embryo quality and the selection of embryos for transfer in clinical IVF practice. Recent studies have suggested that metabolomic profiling of embryo culture media can distinguish human embryos with better implantation potential. …
Website
http://hdl.handle.net/2429/43273
Author
Asghari Roodsari, Alaleh
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2012
Subject
Faculty of Medicine
Theses
Abstract
Light microscopy has remained the primary tool for the assessment of embryo quality and the selection of embryos for transfer in clinical IVF practice. Recent studies have suggested that metabolomic profiling of embryo culture media can distinguish human embryos with better implantation potential. We therefore undertook the following study to further assess the usefulness of metabolomic profiling ?spent? embryo culture medium using Raman spectroscopy. Methods: Patients undergoing IVF+/-ICSI treatment from the UBC Centre for Reproductive Health were recruited for study.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Investigation of methylation and gene expression in placenta of pregnancies conceived by assisted reproductive technology (ART)

https://cwslc.andornot.com/en/permalink/catalog113947
Sakian, Sina. [Vancouver, BC?]: University of British Columbia , 2011.
Website
http://hdl.handle.net/2429/31191
Material Type
Thesis
Call Number
Thesis Shelf
With the increasing use of assisted reproductive techniques (ART) every year, concerns have been raised regarding the possible effect these procedures have on the health of the children procured by them. Although patients born via ART are usually healthy, studies have associated these procedures wi…
Website
http://hdl.handle.net/2429/31191
Author
Sakian, Sina
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2011
Subject
Faculty of Medicine
Theses
Abstract
With the increasing use of assisted reproductive techniques (ART) every year, concerns have been raised regarding the possible effect these procedures have on the health of the children procured by them. Although patients born via ART are usually healthy, studies have associated these procedures with increased incidence of low birth weight (LBW), chromosomal abnormalities, birth defects and imprinting disorders. No study has proposed a single defined cause for any of these defects in ART infants, however it is believed that they may be due to both the invasiveness of ART and to genetic defects that are at the root of the infertility in the parents. In this study, changes in the methylation of the H19 and IGF2 imprinting control region 1 (ICR1) were investigated for both ART (n=92) and naturally conceived controls (n=19) using pyrosequencing.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Regulation of androgen action by sex hormone-binding globulin

https://cwslc.andornot.com/en/permalink/catalog113948
Hong, Eui-ju. [Vancouver, BC?]: University of British Columbia , 2011.
Website
http://hdl.handle.net/2429/35861
Material Type
Thesis
Call Number
Thesis Shelf
Sex hormone-binding globulin (SHBG) binds androgens and estrogens with high affinity, and regulates the distribution of these sex steroids in the blood and other biological fluids. Liver is the primary site of SHBG production, but the human SHBG transcription unit responsible for this is also expre…
Website
http://hdl.handle.net/2429/35861
Author
Hong, Eui-ju
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2011
Subject
Faculty of Medicine
Theses
Abstract
Sex hormone-binding globulin (SHBG) binds androgens and estrogens with high affinity, and regulates the distribution of these sex steroids in the blood and other biological fluids. Liver is the primary site of SHBG production, but the human SHBG transcription unit responsible for this is also expressed in proximal convoluted tubule (PCT) epithelial cells in a transgenic mouse model. Unlike hepatocytes which actively secrete SHBG and retain little immunoreactive SHBG within their cytoplasm, an incompletely glycosylated SHBG isoform has been found to accumulate inside PCT cells. These cells are androgen target cells, and the presence of SHBG within them accentuates androgen-dependent regulation of gene expression mediated by the androgen receptor (AR).
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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The characterization of ADAMTS-12 in the regulation of human trophoblast invasion in vitro

https://cwslc.andornot.com/en/permalink/catalog113949
Zou, Junxuan. [Vancouver, BC?]: University of British Columbia , 2010.
Website
http://hdl.handle.net/2429/29783
Material Type
Thesis
Call Number
Thesis Shelf
The distintegrin-like and metalloproteinase with thrombospondin repeats (ADAMTS) are members of a gene family of secreted, multidomain and multifunctional proteinases that are able to proteolytically degrade a diverse array of cellular, extracellular and extracellular matrix (ECM) substrates. We ex…
Website
http://hdl.handle.net/2429/29783
Author
Zou, Junxuan
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2010
Subject
Faculty of Medicine
Theses
Abstract
The distintegrin-like and metalloproteinase with thrombospondin repeats (ADAMTS) are members of a gene family of secreted, multidomain and multifunctional proteinases that are able to proteolytically degrade a diverse array of cellular, extracellular and extracellular matrix (ECM) substrates. We examined the presence of ADAMTS in first trimester human placenta and only ADAMTS-12 was present in cultures of invasive extravillous cytotrophoblast (EVT) at significantly higher levels than in poorly invasive JEG-3 chorocarcinoma cells. Immunohistochemistry staining of chorionic villi derived from first trimester human placenta demonstrated that ADAMTS-12 was intensively immunolocalized in the cytotrophoblast layer but weakly immunolocalized in the poorly-invasive syncytial trophoblast layer.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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20 records – page 1 of 1.