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2 records – page 1 of 1.

Studies of a sperm acrosomal antigen recognized by HS-63 monoclonal antibody

https://cwslc.andornot.com/en/permalink/catalog113989
Liu, Ming-Sun. [Vancouver, BC?]: University of British Columbia , 1991.
Website
http://hdl.handle.net/2429/30996
Material Type
Thesis
Call Number
Thesis Shelf
A sperm specific and species conserved monoclonal antibody (HS-63) was shown to inhibit in vitro fertilization of mouse oocytes and human sperm penetration to zona-free hamster ova. The sperm antigen (SA-63) which reacts with HS-63 was found to be localized on the sperm acrosome. Following sperm ca…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/30996
Author
Liu, Ming-Sun
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1991
Subject
Faculty of Medicine
Theses
Abstract
A sperm specific and species conserved monoclonal antibody (HS-63) was shown to inhibit in vitro fertilization of mouse oocytes and human sperm penetration to zona-free hamster ova. The sperm antigen (SA-63) which reacts with HS-63 was found to be localized on the sperm acrosome. Following sperm capacitation, this antigen becomes exposed and is shed after the acrosome reaction. SA-63 may be involved in the sperm acrosome reaction during the initial fertilization process.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/30996
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The ontogeny of acyl coenzyme A: cholesterol acyltransferase in rat liver, intestine, adipose tissue, and aorta

https://cwslc.andornot.com/en/permalink/catalog113994
Little, Marie-Terese E. [Vancouver, BC?]: University of British Columbia , 1990.
Website
http://hdl.handle.net/2429/29416
Material Type
Thesis
Call Number
Thesis Shelf
Epidemiological studies have shown that cholesterol is a major risk factor for the development of atherosclerosis. Since the atherosclerotic plaque develops over a long period interventions early in life may be of some benefit. In addition, it has been shown that the enzymes involved in cholesterol…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/29416
Author
Little, Marie-Terese E.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1990
Subject
Faculty of Medicine
Theses
Abstract
Epidemiological studies have shown that cholesterol is a major risk factor for the development of atherosclerosis. Since the atherosclerotic plaque develops over a long period interventions early in life may be of some benefit. In addition, it has been shown that the enzymes involved in cholesterol metabolism can be manipulated in early life. Therefore, studies of the developmental patterns of the key enzymes in cholesterol metabolism are of great importance. Acyl coenzyme A: cholesterol acyltransferase (ACAT) is the primary enzyme which catalyzes the conversion of free cholesterol to cholesterol esters in cells.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/29416
Show Less