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Studies of a sperm acrosomal antigen recognized by HS-63 monoclonal antibody

https://cwslc.andornot.com/en/permalink/catalog113989
Liu, Ming-Sun. [Vancouver, BC?]: University of British Columbia , 1991.
Website
http://hdl.handle.net/2429/30996
Material Type
Thesis
Call Number
Thesis Shelf
A sperm specific and species conserved monoclonal antibody (HS-63) was shown to inhibit in vitro fertilization of mouse oocytes and human sperm penetration to zona-free hamster ova. The sperm antigen (SA-63) which reacts with HS-63 was found to be localized on the sperm acrosome. Following sperm ca…
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Website
http://hdl.handle.net/2429/30996
Author
Liu, Ming-Sun
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1991
Subject
Faculty of Medicine
Theses
Abstract
A sperm specific and species conserved monoclonal antibody (HS-63) was shown to inhibit in vitro fertilization of mouse oocytes and human sperm penetration to zona-free hamster ova. The sperm antigen (SA-63) which reacts with HS-63 was found to be localized on the sperm acrosome. Following sperm capacitation, this antigen becomes exposed and is shed after the acrosome reaction. SA-63 may be involved in the sperm acrosome reaction during the initial fertilization process.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/30996
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