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3 records – page 1 of 1.

Roles of Confined Placental Mosaicism (CPM) and H19/IGF2 imprinting in pregnancies derived from intracytoplasmic sperm injection (ICSI)

https://cwslc.andornot.com/en/permalink/catalog113961
Hatakeyama, Chiho. [Vancouver, BC?]: University of British Columbia , 2007.
Website
http://hdl.handle.net/2429/32719
Material Type
Thesis
Call Number
Thesis Shelf
In contrast to the success of ICSI in treating male infertility, concerns have been raised about the health outcomes of the children conceived through this procedure. Cohort studies have shown that the ICSI population has an increase in low birth weight (LBW), birth defects, chromosomal abnormaliti…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/32719
Author
Hatakeyama, Chiho
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2007
Subject
Faculty of Medicine
Theses
Abstract
In contrast to the success of ICSI in treating male infertility, concerns have been raised about the health outcomes of the children conceived through this procedure. Cohort studies have shown that the ICSI population has an increase in low birth weight (LBW), birth defects, chromosomal abnormalities, and imprinting disorders. However, the underlying causes remain unknown.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/32719
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Fish analysis of chromosomal aneuploidies in spermatozoa from severely infertile men undergoing intracytoplasmic sperm injection (ICSI)

https://cwslc.andornot.com/en/permalink/catalog113969
Gao, Haijun. [Vancouver, BC?]: University of British Columbia , 2004.
Website
http://hdl.handle.net/2429/16195
Material Type
Thesis
Call Number
Thesis Shelf
The association between subsets of male infertility, oligoasthenoteratozoospermia (OAT), obstructive azoospermic (OA), non-obstructive azoospermia (NOA), and increased risk of having chromosomal abnormalities in the sperm has not been investigated. Chromosomal aneuploidy in sperm will be systematic…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/16195
Author
Gao, Haijun
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2004
Subject
Faculty of Medicine
Theses
Abstract
The association between subsets of male infertility, oligoasthenoteratozoospermia (OAT), obstructive azoospermic (OA), non-obstructive azoospermia (NOA), and increased risk of having chromosomal abnormalities in the sperm has not been investigated. Chromosomal aneuploidy in sperm will be systematically investigated by standard methods with large sample sizes required to present significance.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/16195
Show Less

Aneuploidy and DNA fragmentation in morphologically abnormal sperm

https://cwslc.andornot.com/en/permalink/catalog113959
Tang, Steven Siu Yan. [Vancouver, BC?]: University of British Columbia , 2008.
Website
http://hdl.handle.net/2429/945
Material Type
Thesis
Call Number
Thesis Shelf
Intracytoplasmic sperm injection (ICSI) has been a successful assisted reproductive technique for men with severe male-factor infertility. However, ICSI requires the subjective selection of normal looking sperm, which does not preclude the transmission of genetically abnormal sperm. Correlation bet…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/945
Author
Tang, Steven Siu Yan
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2008
Subject
Faculty of Medicine
Theses
Abstract
Intracytoplasmic sperm injection (ICSI) has been a successful assisted reproductive technique for men with severe male-factor infertility. However, ICSI requires the subjective selection of normal looking sperm, which does not preclude the transmission of genetically abnormal sperm. Correlation between abnormal sperm morphology and chromosomal abnormalities has been suggested but not been conclusive and less is known about the connection between sperm morphology and DNA integrity. Sperm morphology will be evaluated on its ability to identify the level of chromosomal abnormalities or fragmented DNA in sperm. To further focus this investigation on sperm morphology, men with infertility isolated to abnormal sperm morphology (isolated teratozoopsermia) are examined.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/945
Show Less