name:"Tang, Steven Siu Yan" found 1 record

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Aneuploidy and DNA fragmentation in morphologically abnormal sperm

https://cwslc.andornot.com/en/permalink/catalog113959

Tang, Steven Siu Yan. [Vancouver, BC?]: University of British Columbia , 2008.

Website: http://hdl.handle.net/2429/945

Material Type: Thesis

Call Number: Thesis Shelf

Intracytoplasmic sperm injection (ICSI) has been a successful assisted reproductive technique for men with severe male-factor infertility. However, ICSI requires the subjective selection of normal looking sperm, which does not preclude the transmission of genetically abnormal sperm. Correlation bet…

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Website: http://hdl.handle.net/2429/945

Author: Tang, Steven Siu Yan

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 2008

Subject: Faculty of Medicine; Theses

Abstract: Intracytoplasmic sperm injection (ICSI) has been a successful assisted reproductive technique for men with severe male-factor infertility. However, ICSI requires the subjective selection of normal looking sperm, which does not preclude the transmission of genetically abnormal sperm. Correlation between abnormal sperm morphology and chromosomal abnormalities has been suggested but not been conclusive and less is known about the connection between sperm morphology and DNA integrity. Sperm morphology will be evaluated on its ability to identify the level of chromosomal abnormalities or fragmented DNA in sperm. To further focus this investigation on sperm morphology, men with infertility isolated to abnormal sperm morphology (isolated teratozoopsermia) are examined.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

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http://hdl.handle.net/2429/945