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2 records – page 1 of 1.

Localization and regulation of mRNA transcripts encoding activin receptors in human placental trophoblast cells

https://cwslc.andornot.com/en/permalink/catalog113978
Chen, Victor. [Vancouver, BC?]: University of British Columbia , 1997.
Website
http://hdl.handle.net/2429/6315
Material Type
Thesis
Call Number
Thesis Shelf
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/6315
Author
Chen, Victor
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1997
Subject
Faculty of Medicine
Theses
Abstract
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type II (II and ILB) receptors. The role of activin in the human placenta is not clearly understood. In this study, the detection of inlubin/activin subunit and ActRI mRNA were examined in first trimester cytotrophoblasts, term cytotrophoblasts, extravillous trophoblast (EVT) cells, immortalized extravillous trophoblast (LEVT) cells, JEG-3 cells, decidual tissue, and decidual cells.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/6315
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Superovulation and chromosomal aberrations

https://cwslc.andornot.com/en/permalink/catalog113983
Ma, Sai. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7516
Material Type
Thesis
Call Number
Thesis Shelf
In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fai…
More Information is Available
  1 website  
Website
http://hdl.handle.net/2429/7516
Author
Ma, Sai
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fail to achieve or sustain implantation. The failure of implantation has raised questions about the possible detrimental effect of superovulation on chromosomal complements. In this study, the hypothesis that chromosomal aberrations exist in mouse preimplantation embryos and human unfertilized oocytes after superovulation, was tested. The incidence of aneuploidy in spontaneously ovulated group (5.6%) was similar to that reported by others.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/7516
Show Less