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Superovulation and chromosomal aberrations

https://cwslc.andornot.com/en/permalink/catalog113983
Ma, Sai. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7516
Material Type
Thesis
Call Number
Thesis Shelf
In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fai…
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  1 website  
Website
http://hdl.handle.net/2429/7516
Author
Ma, Sai
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fail to achieve or sustain implantation. The failure of implantation has raised questions about the possible detrimental effect of superovulation on chromosomal complements. In this study, the hypothesis that chromosomal aberrations exist in mouse preimplantation embryos and human unfertilized oocytes after superovulation, was tested. The incidence of aneuploidy in spontaneously ovulated group (5.6%) was similar to that reported by others.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
http://hdl.handle.net/2429/7516
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