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2 records – page 1 of 1.

Roles of Confined Placental Mosaicism (CPM) and H19/IGF2 imprinting in pregnancies derived from intracytoplasmic sperm injection (ICSI)

https://cwslc.andornot.com/en/permalink/catalog113961
Hatakeyama, Chiho. [Vancouver, BC?]: University of British Columbia , 2007.
Website
http://hdl.handle.net/2429/32719
Material Type
Thesis
Call Number
Thesis Shelf
In contrast to the success of ICSI in treating male infertility, concerns have been raised about the health outcomes of the children conceived through this procedure. Cohort studies have shown that the ICSI population has an increase in low birth weight (LBW), birth defects, chromosomal abnormaliti…
Website
http://hdl.handle.net/2429/32719
Author
Hatakeyama, Chiho
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2007
Subject
Faculty of Medicine
Theses
Abstract
In contrast to the success of ICSI in treating male infertility, concerns have been raised about the health outcomes of the children conceived through this procedure. Cohort studies have shown that the ICSI population has an increase in low birth weight (LBW), birth defects, chromosomal abnormalities, and imprinting disorders. However, the underlying causes remain unknown.
Language
English
Material Type
Thesis
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Superovulation and chromosomal aberrations

https://cwslc.andornot.com/en/permalink/catalog113983
Ma, Sai. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7516
Material Type
Thesis
Call Number
Thesis Shelf
In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fai…
Website
http://hdl.handle.net/2429/7516
Author
Ma, Sai
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fail to achieve or sustain implantation. The failure of implantation has raised questions about the possible detrimental effect of superovulation on chromosomal complements. In this study, the hypothesis that chromosomal aberrations exist in mouse preimplantation embryos and human unfertilized oocytes after superovulation, was tested. The incidence of aneuploidy in spontaneously ovulated group (5.6%) was similar to that reported by others.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less