Website

PHSA Users:

http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp50997&site=pfi-live

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=Nature+medicine

Alternate Title

Nat. Med.

Place of Publication

New York, NY

Publisher

Nature Publishing Group

Publication Date

1995 - Present.

ISSN

1078-8956

Language

English

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.1:1-v.11:7,10,12 (1995-2005); v.12:10 (2006); v.13:3 (2007); v.14:11+suppls. (2008).

Missing: v.1:2,5 (1995); v.4:1,2,6,8-12 (1998); v.5:1-6 (1999); v.6:8 (2000); v.11:8,9,11 (2005); v.12:1-11 (2006); v.13:1-2 (2007).

Online: 1995 to present.

Website

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UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=Journal+of+Molecular+Medicine

Place of Publication

Berlin

Publisher

Springer International Publishing

Publication Date

1864 - Present

ISSN

0946-2716

Language

English

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.82:11-v.85:9 (2004-2007).

Missing: v.83:7-9 (2005); v.84:3,9 (2006).

Online: 1995 to present.

Website

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http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp51617&site=pfi-live

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=I_M&C=0028-4793

Alternate Title

NEJM

Place of Publication

[Boston, MA]

Publisher

Massachusetts Medical Society

Publication Date

1990 - Present.

ISSN

0028-4793

Language

English

Material Type

Serial

Frequency

Weekly

Holdings

CFRI/Study & Learning Commons - Print: v.330:20-v.365:17 (1994-2011).

Missing: v.331:10,12,14,15,19-21 (1994); v.332:20 (1995); v.334:13 (1996); v.337:14 (1997); v.338:2,4,12,22 (1998); v.341:16 (1999); v.342:all (2000); v.343:3,4,6-13,15-17,19,21-22,24-26 (2000); v.344:19-21,23,26; v.345:4,5,7-9,11-13,16,17,20-23,26 (2001); v.346:6-9,14,15,18-20,26 (2002); v.349:5-8,11,12,17,18,24 (2003); v.350:21 (2004); v.353:6,8-13,20 (2005); v.354:7,10,16; v.355:15,18,23 (2006); v.356:2,3,20; v.357:23 (2007); v.358:22,23; v.359:16,18 (2008); v.360:23; v.361:1,9-12 (2009); v.362:4; v.363:21 (2010).

Online: 1990 to present.

Website

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UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=clinical+genetics

Place of Publication

Malden, Ma.

Publisher

John Wiley & Sons, Inc.

Publication Date

1970 - Present.

ISSN

0009-9163

Language

English

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.45:6-v.57:4+special issue (1994-2000); v.61:1 (2002); v.69:3-v.76:3 (2006-2009).

Missing: v.51:3, v.52:4 (1997); v.53:2 (1998); v.55:4, v.56:1,3 (1999); v.57:1-3, v.58:1-6 (2000); v.59:1-6, v.60:1-6 (2001); v.61:2-6, v.62:1-6 (2002); 2003-2005; v.69:1-2 (2006); v.73:3-5 (2008); v.75:1,3,4, v.76:2,4-6 (2009).

Online: 1970 to present.

Website

http://www.nap.edu/catalog.php?record_id=11903

Website Notes

Read online or download as PDF.

Author

Olsen, LeighAnne;

Aisner, Dara;

McGinnis, J. Michael (Eds).

Place of Publication

Washington, DC

Publisher

National Academies Press

Publication Date

2007

Physical Description

374 pages, 2 MB PDF file.

Subject

Health Care Delivery Systems

Evidence-Based Medicine

Abstract

This book considers how health care is structured to develop and to apply evidence--from health profession training and infrastructure development to advances in research methodology, patient engagement, payment schemes, and measurement--and highlights opportunities for the creation of a sustainable learning health care system that gets the right care to people when they need it and then captures the results for improvement. This book will be of primary interest to hospital and insurance industry administrators, health care providers, those who train and educate health workers, researchers, and policymakers.

ISBN

978-0-309-10300-8

Language

English

Material Type

Online

Website

PHSA Users:

http://web.a.ebscohost.com/pfi/detail/detail?vid=15&sid=80dd29ce-f1c9-480f-93d5-346abac169f7%40sessionmgr4009&hid=4106&bdata=JnNpdGU9cGZpLWxpdmU%3d#AN=edp15358&db=edspub

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Alternate Title

Canadian journal of rural medicine : the official journal of the Society of Rural Physicians of Canada = Journal canadien de la médecine rurale : le journal officiel de la Société de médecine rurale du Canada.

Corporate Author

Society of Rural Physicians of Canada

Place of Publication

[Ottawa, ON]

Publisher

Canadian Medical Association

Publication Date

1996 - Present

Notes

Articles in English; some are also in French.

ISSN

1203-7796

Language

English, French

Material Type

Serial

Frequency

Quarterly

Holdings

CFRI/Study & Learning Commons - Print:v.10:1-v.15:4 (2005-2010); v.16:3 (2011); v.17:1-2 (2012).

Missing: v.8:2-4 (2003); v.9:1-4 (2004); v.11:4 (2006); v.12:4 (2007); v.13:2 (2008).

Online: 1996 to present.

Website

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=Human+gene+therapy

Place of Publication

Baltimore, MD

Publisher

Mary Ann Liebert, Inc.

Publication Date

1990 - Present

ISSN

1043-0342

Language

English

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.5:9 (1994); v.6:1-v.13:18 (1995-2002).

Missing: v.8:8 (1997); v.10:17 (1999); v.11:3,4,6-18 (2000); v.12:1-12,14,17,18 (2001); v.13:5 (2002).

Online: 2006 to 2014.

Website

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Place of Publication

Oxford, England

Publisher

Oxford University Press

Publication Date

1992 - Present

ISSN

0964-6906

Language

English

Material Type

Serial

Frequency

Bimonthly

Holdings

CFRI/Study & Learning Commons - Print: v.3:1-v.8:13 (1994-1999); v.9:15-16 (2000); v.10:1-16,19,20,22-25 (2001); v.11:17,20 (2002); v.12:13 (2003).

Missing: v.4:8 (1995); v.5:8 (1996); v.6:8,10 (1997).

Online: 1992 to present.

Website

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Alternate Title

AJHG

Corporate Author

The American Society of Human Genetics

Publisher

Cell Press

ISSN

0002-9297

Material Type

Serial

Frequency

Monthly

Holdings

CFRI/Study & Learning Commons - Print: v.4:1-v.97:6 (1994-2012);

v.93:12-v.94:1 + suppls. (2013-2014)

Missing: v.59:3-5 (1996); v.61:1(1997); v.80:2(2007); v.85:2(2009); v.91:4-5(2009)

Online: 1949 to present (Full Text Delay: 6 months)

Website

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Place of Publication

[Ottawa, ON]

Publisher

Canadian Society for Clinical Investigation (CSCI)

Publication Date

1978 - Present

Notes

Print issues ceased with v. 29, no. 5 (Dec. 2006)

Articles in English; summaries in English and French

ISSN

0147-958X

Language

English

Material Type

Serial

Frequency

Bimonthly

Holdings

CFRI/Study & Learning Commons - Print: v.17:1-v.29:6+suppls.

Missing: v.19:3 (1996); v.24:5 (2001).

Online: 1996 to present.

Website

http://hdl.handle.net/2429/29783

Author

Zou, Junxuan

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2010

Subject

Faculty of Medicine

Theses

Abstract

The distintegrin-like and metalloproteinase with thrombospondin repeats (ADAMTS) are members of a gene family of secreted, multidomain and multifunctional proteinases that are able to proteolytically degrade a diverse array of cellular, extracellular and extracellular matrix (ECM) substrates. We examined the presence of ADAMTS in first trimester human placenta and only ADAMTS-12 was present in cultures of invasive extravillous cytotrophoblast (EVT) at significantly higher levels than in poorly invasive JEG-3 chorocarcinoma cells. Immunohistochemistry staining of chorionic villi derived from first trimester human placenta demonstrated that ADAMTS-12 was intensively immunolocalized in the cytotrophoblast layer but weakly immunolocalized in the poorly-invasive syncytial trophoblast layer.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

http://hdl.handle.net/2429/32051

Author

Peng, Gang

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2007

Subject

Faculty of Medicine

Theses

Abstract

Pre-eclampsia remains one of the most common causes of maternal mortality in the developed world, and we still have no known effective prophylaxis and proven modifiers. The recent successful clinical trial of recombinant human activated protein C (rhAPC) in the management of SIRS (systemic inflammatory response syndrome) has drawn attention to the possible use of this medicine for other conditions. Pre-eclampsia, has remarkable similarity to SIRS and may be such a condition.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

http://hdl.handle.net/2429/9760

Author

Ong, Aldrich Dixon

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

1999

Subject

Faculty of Medicine

Theses

Abstract

Ovarian cancer is the most lethal gynecological cancer in the Western world, but comparatively little is known about its development. Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e. the mesothelium covering the ovary, but experimental evidence for this origin has been lacking. Contrary to most epithelia where neoplastic progression is associated with loss of E-cadherin, this cell-cell adhesion molecule is sparse in normal human OSE but its expression increases in ovarian epithelial metaplasia and neoplasia.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

http://hdl.handle.net/2429/7255

Author

Fan, Nancy C.

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

1995

Subject

Faculty of Medicine

Theses

Abstract

The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling stimulates the synthesis and release of both luteinizing hormone and follicle stimulating hormone from the anterior pituitary. In addition, GnRH - GnRH receptor binding acts locally to regulate human chorionic gonadotropin secretion in the placenta and steroidogenesis in the ovary. The objective of this thesis was to isolate and characterize the gene for the GnRH receptor in human.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

http://hdl.handle.net/2429/3482

Author

Ge, Hong

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

1994

Subject

Faculty of Medicine

Theses

Abstract

This thesis investigated the expression and regulation of cytochrome P450s, aromatase (P450arom) and cholesterol side chain cleavage (P450scc) enzyme mRNAs in human granulosa-luteal cells using reverse transcription-polymerase chain reaction (RT-PCR). The two enzymes are instrumental in steroid hormone biosynthesis.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

http://www.ncbi.nlm.nih.gov/omim

Website Notes

The database corresponds to the print publication.

Author

McKusiak, Victor A (Ed).

Edition

12th Ed.

Place of Publication

Baltimore, MD

Publisher

Johns Hopkins University Press

Publication Date

1998

Physical Description

Hardcover

Subject

Genetics

Genetic Disorders

Genetics/Genetic Disorders-Encyclopedias

Abstract

A comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics.

ISBN

0801857422

Language

English

Material Type

Book

Call Number

REF GI 20 MCK 1998 VOL 1

Copies

Website

http://www.ncbi.nlm.nih.gov/omim

Website Notes

The database corresponds to the print publication.

Author

McKusiak, Victor A (Ed).

Edition

12th Ed.

Place of Publication

Baltimore, MD

Publisher

Johns Hopkins University Press

Publication Date

1998

Physical Description

Hardcover

Subject

Genetics

Genetics/Genetic Disorders-Encyclopedias

Genetic Disorders

Abstract

A comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics.

ISBN

0801857422

Language

English

Material Type

Book

Call Number

REF GI 20 MCK 1998 VOL 2

Copies

Website

http://www.ncbi.nlm.nih.gov/omim

Website Notes

The database corresponds to the print publication.

Author

McKusiak, Victor A (Ed).

Place of Publication

Baltimore, MD

Publisher

Johns Hopkins University Press

Publication Date

1998

Physical Description

Hardcover

Subject

Genetic Disorders

Genetics

Genetics/Genetic Disorders-Encyclopedias

Abstract

A comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics.

ISBN

0801857422

Language

English

Material Type

Book

Call Number

REF GI 20 MCK 1998 VOL 3

Copies

Website

http://hdl.handle.net/2429/6315

Author

Chen, Victor

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

1997

Subject

Faculty of Medicine

Theses

Abstract

There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type II (II and ILB) receptors. The role of activin in the human placenta is not clearly understood. In this study, the detection of inlubin/activin subunit and ActRI mRNA were examined in first trimester cytotrophoblasts, term cytotrophoblasts, extravillous trophoblast (EVT) cells, immortalized extravillous trophoblast (LEVT) cells, JEG-3 cells, decidual tissue, and decidual cells.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf

Website

http://hdl.handle.net/2429/30021

Author

Poon, Song Ling

Place of Publication

[Vancouver, BC?]

Publisher

University of British Columbia

Publication Date

2010

Subject

Faculty of Medicine

Theses

Abstract

It is increasingly apparent that GnRH-II acts as an autocrine/paracrine regulator in non-pituitary tissues, in addition to its role in the regulation of gonadotropin synthesis, and is an important player in cancer cell biology. High levels of GnRH-II and GnRHR in malignant ovarian tumors as compared with benign ovarian tissues underlies the importance of understanding GnRH-II function in ovarian cancer. In an attempt to define the regulation of GnRH-II in these tissues, we found that a cyclic-AMP responsive element (CRE) is critical for GnRH-II promoter transcription.

Language

English

Material Type

Thesis

Call Number

Thesis Shelf