name:"Ong, Aldrich Dixon" found 1 record

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E-cadherin promotes tumorigenicity in human ovarian surface epithelium

https://cwslc.andornot.com/en/permalink/catalog113975

Ong, Aldrich Dixon. [Vancouver, BC?]: University of British Columbia , 1999.

Website: http://hdl.handle.net/2429/9760

Material Type: Thesis

Call Number: Thesis Shelf

Ovarian cancer is the most lethal gynecological cancer in the Western world, but comparatively little is known about its development. Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e. the mesothelium covering the ovary, but experimental evidence fo…

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Website: http://hdl.handle.net/2429/9760

Author: Ong, Aldrich Dixon

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 1999

Subject: Faculty of Medicine; Theses

Abstract: Ovarian cancer is the most lethal gynecological cancer in the Western world, but comparatively little is known about its development. Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e. the mesothelium covering the ovary, but experimental evidence for this origin has been lacking. Contrary to most epithelia where neoplastic progression is associated with loss of E-cadherin, this cell-cell adhesion molecule is sparse in normal human OSE but its expression increases in ovarian epithelial metaplasia and neoplasia.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

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http://hdl.handle.net/2429/9760