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3 records – page 1 of 1.

Action of luteinizing hormone-releasing hormone in rat ovarian cells : hormone production and signal transduction

https://cwslc.andornot.com/en/permalink/catalog113996
Wang, Jian. [Vancouver, BC?]: University of British Columbia , 1989.
Website
http://hdl.handle.net/2429/29313
Material Type
Thesis
Call Number
Thesis Shelf
The present study was conducted to investigate the hypothesis that membrane phosphoinositide breakdown may participate in the actions of luteinizing hormone-releasing hormone (LHRH) on hormone production in the rat ovary. In granulosa cells prelabeled with [³H]-arachidonic acid or [³H]-inositol, tr…
Website
http://hdl.handle.net/2429/29313
Author
Wang, Jian
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1989
Subject
Faculty of Medicine
Theses
Abstract
The present study was conducted to investigate the hypothesis that membrane phosphoinositide breakdown may participate in the actions of luteinizing hormone-releasing hormone (LHRH) on hormone production in the rat ovary. In granulosa cells prelabeled with [³H]-arachidonic acid or [³H]-inositol, treatment with LHRH increased the accumulation of radiolabeled inositol lipids, diacylglycerol and free arachidonic acid, but luteinizing hormone (LH) or cholera toxin did not exert the same effect. Activation of protein kinase C by the phorbol ester, 12-0-tetradecanoyl phorbol-13-acetate (TPA) had a stimulatory action on membrane phosphoinositide breakdown.
Language
English
Material Type
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The effects of superovulation on ovarian function and embryo development in rats

https://cwslc.andornot.com/en/permalink/catalog113997
Yun, Young Won. [Vancouver, BC?]: University of British Columbia , 1989.
Website
http://hdl.handle.net/2429/29326
Material Type
Thesis
Call Number
Thesis Shelf
This study examined primary defects and related mechanisms leading to impaired fertility following superovulation with exogenous gonadotropin. Experiments were designed to address the ovulatory response, oocyte quality (gross morphology and nuclear maturation) and embryo development with reference …
Website
http://hdl.handle.net/2429/29326
Author
Yun, Young Won
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1989
Subject
Faculty of Medicine
Theses
Abstract
This study examined primary defects and related mechanisms leading to impaired fertility following superovulation with exogenous gonadotropin. Experiments were designed to address the ovulatory response, oocyte quality (gross morphology and nuclear maturation) and embryo development with reference to ovarian steroid and circulating LH levels in immature rats treated with 4, 20 or 40 IU pregnant mare's serum gonadotropin (PMSG).
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Studies of sperm antigens using specific monoclonal antibodies

https://cwslc.andornot.com/en/permalink/catalog113995
Sun, Ping. [Vancouver, BC?]: University of British Columbia , 1987.
Website
http://hdl.handle.net/2429/28405
Material Type
Thesis
Call Number
Thesis Shelf
This thesis work is focused on studies of sperm antigen: its purification and antifertility effect, its "internal image" by use of anti-idiotypic antibodies, and its capacity to induce antibodies of IgA class. Mouse sperm acrosomal antigens that react with a monoclonal antibody generated against mo…
Website
http://hdl.handle.net/2429/28405
Author
Sun, Ping
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1987
Subject
Faculty of Medicine
Theses
Abstract
This thesis work is focused on studies of sperm antigen: its purification and antifertility effect, its "internal image" by use of anti-idiotypic antibodies, and its capacity to induce antibodies of IgA class. Mouse sperm acrosomal antigens that react with a monoclonal antibody generated against mouse spermatozoa, MS 207, were purified by immunoaffinity chromatography from soluble fraction of mouse testis homogenates.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less