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10 records – page 1 of 1.

Localization and regulation of mRNA transcripts encoding activin receptors in human placental trophoblast cells

https://cwslc.andornot.com/en/permalink/catalog113978
Chen, Victor. [Vancouver, BC?]: University of British Columbia , 1997.
Website
http://hdl.handle.net/2429/6315
Material Type
Thesis
Call Number
Thesis Shelf
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type…
Website
http://hdl.handle.net/2429/6315
Author
Chen, Victor
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1997
Subject
Faculty of Medicine
Theses
Abstract
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type II (II and ILB) receptors. The role of activin in the human placenta is not clearly understood. In this study, the detection of inlubin/activin subunit and ActRI mRNA were examined in first trimester cytotrophoblasts, term cytotrophoblasts, extravillous trophoblast (EVT) cells, immortalized extravillous trophoblast (LEVT) cells, JEG-3 cells, decidual tissue, and decidual cells.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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The molecular biology of calbindin-D9k

https://cwslc.andornot.com/en/permalink/catalog113987
Jeung, Eui-Bae. [Vancouver, BC?]: University of British Columbia , 1993.
Website
http://hdl.handle.net/2429/1766
Material Type
Thesis
Call Number
Thesis Shelf
Calbindin-D9k is a cytosolic calcium binding protein expressed in the mammalian intestine, placenta, and uterus. The protein is probably involved in calcium transport across the intestinal and placental epithelia. The objective of this thesis was to study the structure of the human and porcine calb…
Website
http://hdl.handle.net/2429/1766
Author
Jeung, Eui-Bae
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1993
Subject
Faculty of Medicine
Theses
Abstract
Calbindin-D9k is a cytosolic calcium binding protein expressed in the mammalian intestine, placenta, and uterus. The protein is probably involved in calcium transport across the intestinal and placental epithelia. The objective of this thesis was to study the structure of the human and porcine calbindin-D9k at the cDNA and genomic level. The cDNAs for the bovine, murine, and ratcalbindin-D9k as well as the gene for rat calbindin-D9k had been cloned previously.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Nature genetics

https://cwslc.andornot.com/en/permalink/catalog119777
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp50993&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=nature+genetics
Alternate Title
Nat. Genet.
Place of Publication
New York, NY
Publisher
Nature Publishing Group
Publication Date
1992 - Present.
ISSN
1061-4036
Language
English
Material Type
Serial
Frequency
Monthly
Holdings
CFRI/Study & Learning Commons - Print: v.6:1-v.46:6+suppls. (1994-2012).
Missing: v.11:1(1995); v.12:1 (1996); v.21:4; v.23:3 (1999); v.27:2; v.28:3 (2001); v.31:2; v.32:4 (2002); v.35:4 (2003).
Online: 1992 to present.
Websites
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Nature medicine

https://cwslc.andornot.com/en/permalink/catalog119779
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp50997&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=Nature+medicine
Alternate Title
Nat. Med.
Place of Publication
New York, NY
Publisher
Nature Publishing Group
Publication Date
1995 - Present.
ISSN
1078-8956
Language
English
Material Type
Serial
Frequency
Monthly
Holdings
CFRI/Study & Learning Commons - Print: v.1:1-v.11:7,10,12 (1995-2005); v.12:10 (2006); v.13:3 (2007); v.14:11+suppls. (2008).
Missing: v.1:2,5 (1995); v.4:1,2,6,8-12 (1998); v.5:1-6 (1999); v.6:8 (2000); v.11:8,9,11 (2005); v.12:1-11 (2006); v.13:1-2 (2007).
Online: 1995 to present.
Websites
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Prostaglandin F[sub 2a]-mediated luteolytic and luteotrophic effects on the human granulosa-luteal cell

https://cwslc.andornot.com/en/permalink/catalog113976
Vaananen, Jeffrey Eric. [Vancouver, BC?]: University of British Columbia , 1997.
Website
http://hdl.handle.net/2429/6811
Material Type
Thesis
Call Number
Thesis Shelf
These studies examined the effects of prostaglandin-F[sub 2a] (PGF[sub 2a]) on progesterone and 178-estradiol (estradiol) production, as well as DNA and PGF[sub 2a]-receptor (PGF[sub 2a]-R) mRNA levels, in the human granulosa-luteal cell (GLC). Additionally, the interactions of PGF[sub 2a] with hum…
Website
http://hdl.handle.net/2429/6811
Author
Vaananen, Jeffrey Eric
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1997
Subject
Faculty of Medicine
Theses
Abstract
These studies examined the effects of prostaglandin-F[sub 2a] (PGF[sub 2a]) on progesterone and 178-estradiol (estradiol) production, as well as DNA and PGF[sub 2a]-receptor (PGF[sub 2a]-R) mRNA levels, in the human granulosa-luteal cell (GLC). Additionally, the interactions of PGF[sub 2a] with human chorionic gonadotrophin (hCG), gonadotrophin-releasing hormone (GnRH) and prostaglandin E₂ (PGE₂) were examined, with respect to progesterone and estradiol production.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Regulation of cytochrome P450 and P450 mRNA in human granulosa-luteal cells

https://cwslc.andornot.com/en/permalink/catalog113984
Ge, Hong. [Vancouver, BC?]: University of British Columbia , 1994.
Website
http://hdl.handle.net/2429/3482
Material Type
Thesis
Call Number
Thesis Shelf
This thesis investigated the expression and regulation of cytochrome P450s, aromatase (P450arom) and cholesterol side chain cleavage (P450scc) enzyme mRNAs in human granulosa-luteal cells using reverse transcription-polymerase chain reaction (RT-PCR). The two enzymes are instrumental in steroid hor…
Website
http://hdl.handle.net/2429/3482
Author
Ge, Hong
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1994
Subject
Faculty of Medicine
Theses
Abstract
This thesis investigated the expression and regulation of cytochrome P450s, aromatase (P450arom) and cholesterol side chain cleavage (P450scc) enzyme mRNAs in human granulosa-luteal cells using reverse transcription-polymerase chain reaction (RT-PCR). The two enzymes are instrumental in steroid hormone biosynthesis.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Single cell studies of calcium as second messenger in human granulosa-lutein and embryonic kidney 293 cells

https://cwslc.andornot.com/en/permalink/catalog113979
Lee, Pearly S.N. [Vancouver, BC?]: University of British Columbia , 1999.
Website
http://hdl.handle.net/2429/10789
Material Type
Thesis
Call Number
Thesis Shelf
It is well established that LH action is mediated primarily by adenylate cyclase/cAMP. Conversely, the role of inositol phosphate/calcium in LH signalling has only recently been investigated. We examined the effects of gonadotrophins on intracellular calcium mobilisation in HEK293 cells transiently…
Website
http://hdl.handle.net/2429/10789
Author
Lee, Pearly S.N.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1999
Subject
Faculty of Medicine
Theses
Abstract
It is well established that LH action is mediated primarily by adenylate cyclase/cAMP. Conversely, the role of inositol phosphate/calcium in LH signalling has only recently been investigated. We examined the effects of gonadotrophins on intracellular calcium mobilisation in HEK293 cells transiently transfected with human wild type or chimeric gonadotrophs receptors (n=3400). Intracellular free calcium concentration was measured using fura-2 microspectrofluorimetric techniques. Human LH (2-4 μg/ml) arid CG (10 IU/ml) consistently evoked oscillatory calcium signals in HEK293 cells transfected with hLHr, whereas hFSH (2-4 μg/ml) failed to elicit any calcium responses.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Trends in cell biology

https://cwslc.andornot.com/en/permalink/catalog119853
Website
PHSA Users:
Not available online.
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=I_M&C=0962-8924
Place of Publication
Cambridge, Ma.
Publisher
Elsevier Inc.
Publication Date
1990 - Present.
ISSN
0962-8924
Language
English
Material Type
Serial
Frequency
Monthly
Holdings
CFRI/Study & Learning Commons - Print: v.4:10-v.8:12 (1994-1998); v.9:1,6 (1999); v.11:12-v.24:2 (2001-2014).
Missing: v.4:11 (1994); v.5:1 (1995); v.8:3 (1998); v.9:2-5,7-12 (1999); v.10:all (2000); v.13:12 (2003); v.14:1-2 (2004).
Online: 1990 to present.
Websites
Show Less

10 records – page 1 of 1.