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A Biological role for GnRH I and GnRH II at the maternal-fetal interface

https://cwslc.andornot.com/en/permalink/catalog113971
Zhou, Junshan. [Vancouver, BC?]: University of British Columbia , 2003.
Website
http://hdl.handle.net/2429/14957
Material Type
Thesis
Call Number
Thesis Shelf
Remodeling of the endometrial extracellular matrix, which occurs during the early stages of pregnancy in the human, is mediated by the temporal expression of urokinase-type plasminogen activator (uPA) and matrix metalloproteinases (MMP) in both the maternal and fetal compartments and counterbalance…
Website
http://hdl.handle.net/2429/14957
Author
Zhou, Junshan
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2003
Subject
Faculty of Medicine
Theses
Abstract
Remodeling of the endometrial extracellular matrix, which occurs during the early stages of pregnancy in the human, is mediated by the temporal expression of urokinase-type plasminogen activator (uPA) and matrix metalloproteinases (MMP) in both the maternal and fetal compartments and counterbalanced by their respective endogenous inhibitors, plasminogen activator inhibitor (PAI-1) and tissue inhibitors of metalloproteinases (TIMPs) in both an autocrine and paracrine manner. To date, the factors capable of regulating the expression of uPA and MMP proteolytic systems at the maternal-fetal interface remain poorly characterized.
Language
English
Material Type
Thesis
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Thesis Shelf
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