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12 records – page 1 of 1.

Role of receptor tyrosine kinase regulator Sprouty in ovarian cancer cells

https://cwslc.andornot.com/en/permalink/catalog113944
So, Wai Kin. [Vancouver, BC?]: University of British Columbia , 2012.
Website
http://hdl.handle.net/2429/42242
Material Type
Thesis
Call Number
Thesis Shelf
Aberrant epidermal growth factor receptor (EGFR) activity contributes to the development of epithelial ovarian cancer (EOC), a common and lethal female malignancy. Elucidating the regulation of EGFR function will improve treatments for EOC and the survival of patients. This study aims to elucidate …
Website
http://hdl.handle.net/2429/42242
Author
So, Wai Kin
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2012
Subject
Faculty of Medicine
Theses
Abstract
Aberrant epidermal growth factor receptor (EGFR) activity contributes to the development of epithelial ovarian cancer (EOC), a common and lethal female malignancy. Elucidating the regulation of EGFR function will improve treatments for EOC and the survival of patients. This study aims to elucidate the role of Sprouty (SPRY) proteins, which are EGFR regulators, in EOC.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Noninvasive assessment of embryo quality in human in vitro fertilization : metabolomic profiling of embryo culture media with Raman spectroscopy

https://cwslc.andornot.com/en/permalink/catalog113946
Asghari Roodsari, Alaleh. [Vancouver, BC?]: University of British Columbia , 2012.
Website
http://hdl.handle.net/2429/43273
Material Type
Thesis
Call Number
Thesis Shelf
Light microscopy has remained the primary tool for the assessment of embryo quality and the selection of embryos for transfer in clinical IVF practice. Recent studies have suggested that metabolomic profiling of embryo culture media can distinguish human embryos with better implantation potential. …
Website
http://hdl.handle.net/2429/43273
Author
Asghari Roodsari, Alaleh
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2012
Subject
Faculty of Medicine
Theses
Abstract
Light microscopy has remained the primary tool for the assessment of embryo quality and the selection of embryos for transfer in clinical IVF practice. Recent studies have suggested that metabolomic profiling of embryo culture media can distinguish human embryos with better implantation potential. We therefore undertook the following study to further assess the usefulness of metabolomic profiling ?spent? embryo culture medium using Raman spectroscopy. Methods: Patients undergoing IVF+/-ICSI treatment from the UBC Centre for Reproductive Health were recruited for study.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Communicating risks and benefits: An evidence-based user's guide

https://cwslc.andornot.com/en/permalink/catalog111871
Fischhoff, Baruch, Brewer, Noel T., Downs, Julie S.(eds.). Maryland, USA: FDA, US Department of Health & Human Services , 2011.
Website
http://www.cw.bc.ca/library/pdf/Risk communication book remediated2.pdf
Material Type
Book
Online
Effective risk communication is essential to the well-being of any organization and those people who depend on it. Ineffective communication can cost lives, money, and reputations. Communicating Risks and Benefits: An Evidence-Based User's Guide provides the scientific foundations for effective …
Website
http://www.cw.bc.ca/library/pdf/Risk communication book remediated2.pdf
Website Notes
Click on the link above to view/print.
Author
Fischhoff, Baruch
Brewer, Noel T.
Downs, Julie S.(eds.)
Corporate Author
Food & Drug Administration (FDA), US Department of Health & Human Services
Place of Publication
Maryland, USA
Publisher
FDA, US Department of Health & Human Services
Publication Date
2011
Physical Description
PDF file: 242 p.
Subject
Leadership/Coaching
Communication
Abstract
Effective risk communication is essential to the well-being of any organization and those people who depend on it. Ineffective communication can cost lives, money, and reputations. Communicating Risks and Benefits: An Evidence-Based User's Guide provides the scientific foundations for effective communication.
Language
English
Material Type
Book
Online
Websites
Show Less

Human gonadotropin-releasing hormone-II regulation in ovarian cancer : mechanisms and potential functional role

https://cwslc.andornot.com/en/permalink/catalog113953
Poon, Song Ling. [Vancouver, BC?]: University of British Columbia , 2010.
Website
http://hdl.handle.net/2429/30021
Material Type
Thesis
Call Number
Thesis Shelf
It is increasingly apparent that GnRH-II acts as an autocrine/paracrine regulator in non-pituitary tissues, in addition to its role in the regulation of gonadotropin synthesis, and is an important player in cancer cell biology. High levels of GnRH-II and GnRHR in malignant ovarian tumors as compare…
Website
http://hdl.handle.net/2429/30021
Author
Poon, Song Ling
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2010
Subject
Faculty of Medicine
Theses
Abstract
It is increasingly apparent that GnRH-II acts as an autocrine/paracrine regulator in non-pituitary tissues, in addition to its role in the regulation of gonadotropin synthesis, and is an important player in cancer cell biology. High levels of GnRH-II and GnRHR in malignant ovarian tumors as compared with benign ovarian tissues underlies the importance of understanding GnRH-II function in ovarian cancer. In an attempt to define the regulation of GnRH-II in these tissues, we found that a cyclic-AMP responsive element (CRE) is critical for GnRH-II promoter transcription.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Book of awesome: Snow days, bakery air, finding money in your pocket, and other simple, brilliant things

https://cwslc.andornot.com/en/permalink/catalog112885
Pasricha, Neil. New York, NY: Berkley , 2010.
Website
1000awesomethings.com
Material Type
Book
Call Number
REF AA 75 PAS 2010
Availability
1 copy, 1 available
The Book of Awesome is a high five for humanity and a big celebration of life's little moments and the underappreciated, simple things that make us happy.
Website
1000awesomethings.com
Author
Pasricha, Neil
Place of Publication
New York, NY
Publisher
Berkley
Publication Date
2010
Physical Description
Paperback: 393 p.
Subject
Leadership/Coaching
Abstract
The Book of Awesome is a high five for humanity and a big celebration of life's little moments and the underappreciated, simple things that make us happy.
ISBN
9780425238905
Language
English
Material Type
Book
Call Number
REF AA 75 PAS 2010

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF AA 75 PAS 2010 MISSING Available
Websites
Show Less

Start with why: How great leaders inspire everyone to take action

https://cwslc.andornot.com/en/permalink/catalog112839
Sinek, Simon. New York, NY: Penguin Group , 2009.
Website
http://www.startwithwhy.com/Portals/0/Downloads/StartWithWHYChapter.pdf
Material Type
Book
Call Number
REF AA 75 SIN 2009
Availability
4 copies, 3 available
This book offers an unconventional perspective that explains why some people and organizations are more innovative, more profitable, command greater loyalties from customers and employees alike and, most importantly, are able to repeat their success over and over.
  1 image     1 website  
Website
http://www.startwithwhy.com/Portals/0/Downloads/StartWithWHYChapter.pdf
Author
Sinek, Simon
Place of Publication
New York, NY
Publisher
Penguin Group
Publication Date
2009
Physical Description
Paperback: 246 pages
Subject
Leadership/Coaching
Abstract
This book offers an unconventional perspective that explains why some people and organizations are more innovative, more profitable, command greater loyalties from customers and employees alike and, most importantly, are able to repeat their success over and over.
ISBN
9781591846444
Language
English
Material Type
Book
Call Number
REF AA 75 SIN 2009

Copies

Copy 2 BC Children's and Women's Study and Learning Commons REF On Loan, due Friday, April 3, 2020
Copy 1 BC Children's and Women's Study and Learning Commons Missing Available
Copy 3 BC Children's and Women's Study and Learning Commons REF Available
Copy 4 BC Children's and Women's Study and Learning Commons REF Available
Images
Websites
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Roles of Confined Placental Mosaicism (CPM) and H19/IGF2 imprinting in pregnancies derived from intracytoplasmic sperm injection (ICSI)

https://cwslc.andornot.com/en/permalink/catalog113961
Hatakeyama, Chiho. [Vancouver, BC?]: University of British Columbia , 2007.
Website
http://hdl.handle.net/2429/32719
Material Type
Thesis
Call Number
Thesis Shelf
In contrast to the success of ICSI in treating male infertility, concerns have been raised about the health outcomes of the children conceived through this procedure. Cohort studies have shown that the ICSI population has an increase in low birth weight (LBW), birth defects, chromosomal abnormaliti…
Website
http://hdl.handle.net/2429/32719
Author
Hatakeyama, Chiho
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2007
Subject
Faculty of Medicine
Theses
Abstract
In contrast to the success of ICSI in treating male infertility, concerns have been raised about the health outcomes of the children conceived through this procedure. Cohort studies have shown that the ICSI population has an increase in low birth weight (LBW), birth defects, chromosomal abnormalities, and imprinting disorders. However, the underlying causes remain unknown.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Gonadotropins and leptin : the role and molecular mechanism in normal and neoplastic ovarian epithelium cells

https://cwslc.andornot.com/en/permalink/catalog113965
Choi, Jung-Hye. [Vancouver, BC?]: University of British Columbia , 2006.
Website
http://hdl.handle.net/2429/18509
Material Type
Thesis
Call Number
Thesis Shelf
Ovarian cancer is the sixth most common cancer and the fifth leading cause of cancer-related death among women in developed countries. There is increasing evidence suggesting that the hormonal environment of the normal ovarian surface epithelium (OSE) and ovarian epithelial cancer (OEC) cells is as…
Website
http://hdl.handle.net/2429/18509
Author
Choi, Jung-Hye
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2006
Subject
Faculty of Medicine
Theses
Abstract
Ovarian cancer is the sixth most common cancer and the fifth leading cause of cancer-related death among women in developed countries. There is increasing evidence suggesting that the hormonal environment of the normal ovarian surface epithelium (OSE) and ovarian epithelial cancer (OEC) cells is associated with the development and progression of ovarian cancer. Exposure to excess gonadotropins and leptin, related to menopause or infertility therapy and obesity, respectively, has been implicated as a risk factor for ovarian cancer.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Creating a culture of collaboration

https://cwslc.andornot.com/en/permalink/catalog109693
Schuman, Sandy (Ed.). San Francisco, CA: Jossey-Bass , 2006.
Website
http://www.josseybass.com/WileyCDA/WileyTitle/productCd-0787981168.html
Material Type
Book
Call Number
REF AA 500 SCH 2006
Availability
1 copy, 1 available
Collaboration is often viewed as a one-time or project-oriented activity. An increasing challenge is to help organizations incorporate collaborative values and practices in their everyday ways of working. In Creating a Culture of Collaboration, an international group of practitioners and researcher…
Website
http://www.josseybass.com/WileyCDA/WileyTitle/productCd-0787981168.html
Author
Schuman, Sandy (Ed.)
Corporate Author
International Association of Facilitators
Place of Publication
San Francisco, CA
Publisher
Jossey-Bass
Publication Date
2006
Physical Description
Hardcover, 498 p.
Series
Business & Management Series
Subject
Administration
Abstract
Collaboration is often viewed as a one-time or project-oriented activity. An increasing challenge is to help organizations incorporate collaborative values and practices in their everyday ways of working. In Creating a Culture of Collaboration, an international group of practitioners and researchers–from Australia, Belgium, Canada, Chile, New Zealand, Northern Ireland, United Kingdom, and the United States–provide proven approaches to creating a culture of collaboration within and among groups, organizations, communities, and societies.
ISBN
0-7879-8116-8
Language
English
Material Type
Book
Call Number
REF AA 500 SCH 2006

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
Websites
Show Less

A Biological role for GnRH I and GnRH II at the maternal-fetal interface

https://cwslc.andornot.com/en/permalink/catalog113971
Zhou, Junshan. [Vancouver, BC?]: University of British Columbia , 2003.
Website
http://hdl.handle.net/2429/14957
Material Type
Thesis
Call Number
Thesis Shelf
Remodeling of the endometrial extracellular matrix, which occurs during the early stages of pregnancy in the human, is mediated by the temporal expression of urokinase-type plasminogen activator (uPA) and matrix metalloproteinases (MMP) in both the maternal and fetal compartments and counterbalance…
Website
http://hdl.handle.net/2429/14957
Author
Zhou, Junshan
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2003
Subject
Faculty of Medicine
Theses
Abstract
Remodeling of the endometrial extracellular matrix, which occurs during the early stages of pregnancy in the human, is mediated by the temporal expression of urokinase-type plasminogen activator (uPA) and matrix metalloproteinases (MMP) in both the maternal and fetal compartments and counterbalanced by their respective endogenous inhibitors, plasminogen activator inhibitor (PAI-1) and tissue inhibitors of metalloproteinases (TIMPs) in both an autocrine and paracrine manner. To date, the factors capable of regulating the expression of uPA and MMP proteolytic systems at the maternal-fetal interface remain poorly characterized.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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The role for insulin-like growth factor-I in preimplantation embryonic development and decidualization following superovulation in the rat

https://cwslc.andornot.com/en/permalink/catalog113980
Katagiri, Seiji. [Vancouver, BC?]: University of British Columbia , 1996.
Website
http://hdl.handle.net/2429/4814
Material Type
Thesis
Call Number
Thesis Shelf
Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation…
Website
http://hdl.handle.net/2429/4814
Author
Katagiri, Seiji
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1996
Subject
Faculty of Medicine
Theses
Abstract
Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation in the rat. IGF-I may be beneficial to preimplantation embryonic development. IGF-I stimulated embryonic development and metabolism in vitro and increased the rate of implantation and fetal development when the blastocysts were transferred into a receptive uterus.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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The role of norepinephrine in the neuroendocrine regulation of luteinizing hormone release in the rat

https://cwslc.andornot.com/en/permalink/catalog113999
Bergen, Hugo Theodore. [Vancouver, BC?]: University of British Columbia , 1988.
Website
http://hdl.handle.net/2429/28623
Material Type
Thesis
Call Number
Thesis Shelf
An excitatory role for norepinephrine (NE) in the regulation of luteinizing hormone (LH) release was first suggested when it was demonstrated that noradrenergic receptor antagonists were able to block ovulation. More recently it has been proposed that NE has both an excitatory role and an inhibitor…
Website
http://hdl.handle.net/2429/28623
Author
Bergen, Hugo Theodore
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1988
Subject
Faculty of Medicine
Theses
Abstract
An excitatory role for norepinephrine (NE) in the regulation of luteinizing hormone (LH) release was first suggested when it was demonstrated that noradrenergic receptor antagonists were able to block ovulation. More recently it has been proposed that NE has both an excitatory role and an inhibitory role in the neuroendocrine regulation of LH release. The excitatory effects may be mediated by alpha-adrenergic receptors and the inhibitory effects may be mediated via beta-adrenergic receptors. These experiments were performed to better understand the role of NE, the receptor type through which NE exerts its effects, and the role of the two major NE pathways in the brain, on LH secretion in the rat.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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12 records – page 1 of 1.