Browse and borrow resources that support the learning needs and professional development of C&W staff, clinicians, students and faculty.
The distintegrin-like and metalloproteinase with thrombospondin repeats (ADAMTS) are members of a gene family of secreted, multidomain and multifunctional proteinases that are able to proteolytically degrade a diverse array of cellular, extracellular and extracellular matrix (ECM) substrates. We ex…
With the increasing use of assisted reproductive techniques (ART) every year, concerns have been raised regarding the possible effect these procedures have on the health of the children procured by them. Although patients born via ART are usually healthy, studies have associated these procedures wi…
Activin A (homodimer of inhibin βA-subunit) is known to increase inhibin βB-subunit and inhibin B (heterodimer of inhibin α- and βB-subunit) levels and decrease progesterone accumulation in human granulosa cells. Growth differentiation factor 9 (GDF9) is a potent paracrine regul…
Sex hormone-binding globulin (SHBG) binds androgens and estrogens with high affinity, and regulates the distribution of these sex steroids in the blood and other biological fluids. Liver is the primary site of SHBG production, but the human SHBG transcription unit responsible for this is also expre…
Aberrant epidermal growth factor receptor (EGFR) activity contributes to the development of epithelial ovarian cancer (EOC), a common and lethal female malignancy. Elucidating the regulation of EGFR function will improve treatments for EOC and the survival of patients. This study aims to elucidate …
It is increasingly apparent that GnRH-II acts as an autocrine/paracrine regulator in non-pituitary tissues, in addition to its role in the regulation of gonadotropin synthesis, and is an important player in cancer cell biology. High levels of GnRH-II and GnRHR in malignant ovarian tumors as compare…
Disruptions or imbalances of the vaginal microbiome can lead to negative reproductive health consequences for women, including an increased risk of sexually transmitted infections, pelvic inflammatory disease, and preterm birth. HIV-positive women may be particularly vulnerable to microbiome disrup…
Human newborns exposed in utero to maternally administered SSRIs such as fluoxetine (FX) have an increased risk of adverse pregnancy outcomes including poor neonatal adaptation. This comprises respiratory difficulty, jitteriness, cyanosis when feeding and persists for several days after birth. Seve…
Pregnancies derived from in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are associated with increased rates of chromosome abnormalities, congenital malformations, low birth weight, pre-term births, multiple gestations, and imprinting disorders. Assisted reproductive techno…
Light microscopy has remained the primary tool for the assessment of embryo quality and the selection of embryos for transfer in clinical IVF practice. Recent studies have suggested that metabolomic profiling of embryo culture media can distinguish human embryos with better implantation potential. …
Abnormal DNA methylation at imprinted and non-imprinted genes has been associated with spermatogenesis failure. However, little information is available regarding DNA methylation at those genes in men affected by severe male factor infertility. We hypothesized a higher incidence of aberrant DNA met…
Nuclear receptors including estrogen receptors (ERs) and progesterone receptors (PRs) are activated by their ligands as well as by signaling pathways in response to peptide hormones and growth factors. In gonadotrophs, gonadotropin releasing hormones (GnRHs) act via the GnRH receptor (GnRHR). Both …
In-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) are two of the most common forms of assisted reproductive technologies (ARTs) used to treat human infertility. Presently, over two million children have been conceived by ART. The majority of these children are born healthy. H…
Copy 1 BC Children's and Women's Study and Learning Commons Thesis Shelf | Available |
This text boils down your coursework to just the critical concepts you need to know for exam success. Features a quick-read, two-column, “flashcard in a book” Q&A format. – specifically designed to help you remember a large amount of pertinent information in the least amount of time possible. The f…
Copy 1 BC Children's and Women's Study and Learning Commons REF | Available |
Highly acclaimed in its first three editions, McWhinney's Textbook of Family Medicine is one of the seminal texts in the field. While many family medicine texts simply cover the disorders a practitioner might see in clinical practice, McWhinney's defines the principles and practices of family medic…
Copy 1 BC Children's and Women's Study and Learning Commons REF | Available |
This resource provides students with a complete review of key concepts and topics and serves as a rapid reference during day-to-day activities in patient care—perfect for clerkship rotations and the USMLE.
Copy 1 BC Children's and Women's Study and Learning Commons REF | Available |
This resource provides students with a complete review of key concepts and topics and serves as a rapid reference during day-to-day activities in patient care—perfect for clerkship rotations and the USMLE.
Copy 1 BC Children's and Women's Study and Learning Commons REF | Available | ||
Copy 2 BC Children's and Women's Study and Learning Commons REF- MISSING | Available |
This text boils down your coursework to just the critical concepts you need to know for exam success. This unbeatable guide features a quick-read, two-column "flashcard" Q&A format--specifically designed to help you remember a large amount of pertinent information in the least amount of time possib…
Copy 1 BC Children's and Women's Study and Learning Commons REF | Available |
This text is written and designed principally for students of medicine adn the related health sciences. Pathology is presented in the context of modern cellular and molecular biology and contemporary clinical practice.
Copy 1 BC Children's and Women's Study and Learning Commons REF | Available |
Underwood?s Pathology (formerly General and Systematic Pathology) is an internationally popular and highly acclaimed textbook, written and designed principally for students of medicine and the related health sciences. Pathology is presented in the context of modern cellular and molecular biology an…
Copy 1 BC Children's and Women's Study and Learning Commons REF | Available |