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Harwood-Nuss' Clinical Practice of Emergency Medicine

https://cwslc.andornot.com/en/permalink/catalog125198
King, Brent, Loiselle, John. Philadelphia, PA: Wolters Kluwer , 2020. 6th.
Material Type
Book
Call Number
REF EB 800 WOL 2020
Availability
1 copy, 1 available
Harwood-Nuss' Clinical Practice of Emergency Medicine presents a clinically focused and evidence-based summary of emergency medicine. Chapters are templated to include the clinical presentation, differential diagnosis, evaluation, management and disposition, with highlighted critical interventions …
Author
King, Brent
Loiselle, John
Editor
Wolfson, Allan B
Edition
6th
Place of Publication
Philadelphia, PA
Publisher
Wolters Kluwer
Publication Date
2020
Physical Description
Hardcover, 1860 pp
Subjects
Pediatrics
Emergency Procedures
Subject
Emergency Medicine
Abstract
Harwood-Nuss' Clinical Practice of Emergency Medicine presents a clinically focused and evidence-based summary of emergency medicine. Chapters are templated to include the clinical presentation, differential diagnosis, evaluation, management and disposition, with highlighted critical interventions and common pitfalls. Management and disposition are especially critical in the emergency department, and their emphasis is unique to Harwood-Nuss. Often, a diagnosis can not be made, given the constraints of an ED evaluation; thus, effecive management of the patient, with or without a confirmed diagnosis, is key. Also distinct to Harwood-Nuss is the High-Risk Chief Complaints section, which covers the key presentations in the ED: chest pain, abdominal pain, shortness of breath, altered mental status. When patients present in the ED, they don't present with a known diagnosis; this chapter walks the physician through possible differential diagnoses and the evaluation and management of these patients so that they can be stabilized and treated quickly and effectively.
ISBN
978-1451188813
Language
English
Material Type
Book
Call Number
REF EB 800 WOL 2020

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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Washington manual of medical therapeutics

https://cwslc.andornot.com/en/permalink/catalog123797
Foster, Cory, Mistry, Neville, F. Philadelphia, PA: Lippincott Williams & Wilkins , 2020. 36th Ed.
Material Type
Book
Call Number
REF FA 100 FOS 2020
Availability
1 copy, 1 available
Established for more than 75 years,The Washington Manual of Medical Therapeutics, 36th Edition, provides concise, high-yield content that reflects today's fast-changing advances in medical technology and therapeutics. In one convenient, portable resource, you'll find complete coverage of every area…
Author
Foster, Cory
Mistry, Neville, F.
Edition
36th Ed.
Place of Publication
Philadelphia, PA
Publisher
Lippincott Williams & Wilkins
Publication Date
2020
Physical Description
Paperback; 1074 pages.
Subject
General Medicine
UBC MD Undergrad
Abstract
Established for more than 75 years,The Washington Manual of Medical Therapeutics, 36th Edition, provides concise, high-yield content that reflects today's fast-changing advances in medical technology and therapeutics. In one convenient, portable resource, you'll find complete coverage of every area of medicine and the core subspecialties?all at your fingertips for quick review and reference. Discover why housestaff and faculty worldwide depend on this best-selling resource for day-to-day clinical practice in internal medicine.
ISBN
978-1975-113483
Language
English
Material Type
Book
Call Number
REF FA 100 FOS 2020

Copies

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Vancouver Notes for Internal Medicine: High-Yield Consult Guides

https://cwslc.andornot.com/en/permalink/catalog125185
Vancouver, BC: Brush Education , 2022.
Material Type
Book
Call Number
REF AB 22 TAN 2022
Availability
2 copies, 2 available
A point-of-care guide for internal medicine trainees; When students and residents begin a new rotation in internal medicine, they often start from scratch, relying on their own research to prepare for consultations. What questions are crucial during history taking? What should the physical examinat…
Editor
Tang, Brandon
Zhuang, Meiying
Tessaro, James
Place of Publication
Vancouver, BC
Publisher
Brush Education
Publication Date
2022
Physical Description
424 pp
Subjects
Internal Medicine
Subject
Medical Directories. Resource Guides
UBC MD Undergrad
Abstract
A point-of-care guide for internal medicine trainees
When students and residents begin a new rotation in internal medicine, they often start from scratch, relying on their own research to prepare for consultations. What questions are crucial during history taking? What should the physical examination and investigations focus on? What should the consultation write-up include? Now, physician learners can turn to Vancouver Notes for Internal Medicine for guidance on conducting consultations in each of the core internal medicine subspecialties.
Vancouver Notes provides learners with an organized approach to common presentations in internal medicine. For each subspecialty, it lays out the process for identifying key information and communicating findings and management recommendations to a patient?s health-care team. Developed through the efforts of more than 90 resident physicians and faculty members at the University of British Columbia, Vancouver Notes combines valuable clinical pearls in a single, accessible resource to give students and residents the tools they need to succeed from day one.
ISBN
978-1550598995
Language
English
Material Type
Book
Call Number
REF AB 22 TAN 2022

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Step-up to medicine

https://cwslc.andornot.com/en/permalink/catalog123790
Agabegi, Steven, Agabegi, Elizabeth. Philadelphia, PA: Lippincott Williams & Wilkins , 2020. 5th ed.
Material Type
Book
Call Number
REF AB 22 AGA 2020
Availability
1 copy, 1 available
This bestselling volume in the popular Step-Up series provides a high-yield review of medicine, ideal for preparing for clerkships or clinical rotations, shelf exams, and the USMLE Step 2. Clinical pearls, full-color illustrations, and ?Quick Hits provide essential information in an efficient, easy…
Author
Agabegi, Steven
Agabegi, Elizabeth
Edition
5th ed.
Place of Publication
Philadelphia, PA
Publisher
Lippincott Williams & Wilkins
Publication Date
2020
Physical Description
582 pp
Subject
Medical Directories. Resource Guides
UBC MD Undergrad
Abstract
This bestselling volume in the popular Step-Up series provides a high-yield review of medicine, ideal for preparing for clerkships or clinical rotations, shelf exams, and the USMLE Step 2. Clinical pearls, full-color illustrations, and ?Quick Hits provide essential information in an efficient, easy-to-remember manner to help you excel on your exams and succeed in the clinical setting. Also includes a 100-question practice exam to support preparation.
ISBN
978-1975-103613
Language
English
Material Type
Book
Call Number
REF AB 22 AGA 2020

Copies

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Bates' guide to physical examination and history taking

https://cwslc.andornot.com/en/permalink/catalog123792
Bickley, Lynn S., Szilagyi, Peter G. Philadelphia, PA: Lippincott Williams & Wilkins , 2023. 13th Ed.
Material Type
Book
Call Number
REF FA 100 BIC 2023
Availability
1 copy, 1 available
Confidently Perform Accurate, Efficient, and Effective Physical Examinations.; Master the techniques for successful physical examinations with the #1 choice for complete, authoritative guidance. This highly regarded text in book-only format includes fully-illustrated, step-by-step techniques that o…
Author
Bickley, Lynn S.
Szilagyi, Peter G.
Edition
13th Ed.
Place of Publication
Philadelphia, PA
Publisher
Lippincott Williams & Wilkins
Publication Date
2023
Physical Description
Hardcover: 1024 p.
Subject
General Medicine
Diagnostic Tests/Procedures. Physical Diagnosis
UBC MD Undergrad
Abstract
Confidently Perform Accurate, Efficient, and Effective Physical Examinations.
Master the techniques for successful physical examinations with the #1 choice for complete, authoritative guidance. This highly regarded text in book-only format includes fully-illustrated, step-by-step techniques that outline the correct performance of the physical examination and an easy-to-follow two-column format that correlates examination techniques on the left and abnormalities (clearly indicated in red) with differential diagnoses on the right.
ISBN
978-1975210533
Language
English
Material Type
Book
Call Number
REF FA 100 BIC 2023

Copies

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Pocket medicine: The Massachusetts general hospital handbook of internal medicine

https://cwslc.andornot.com/en/permalink/catalog123803
Sabatine, Marc S. Philadelphia, PA: Wolters Kluwer , 2020. 7th ed.
Material Type
Book
Call Number
WB 115 S23 2020
Availability
1 copy, 1 available
Quick access to key clinical information and solutions to common problems in internal medicine - as close as your pocket!Pocket Medicine, Seventh Edition, is your go-to resource for fast answers to diagnostic questions you'll face on rounds and exams. Prepared by residents and attending physicians …
Author
Sabatine, Marc S.
Edition
7th ed.
Place of Publication
Philadelphia, PA
Publisher
Wolters Kluwer
Publication Date
2020
Physical Description
Softcover, 280 p., ill.
Abstract
Quick access to key clinical information and solutions to common problems in internal medicine - as close as your pocket!Pocket Medicine, Seventh Edition, is your go-to resource for fast answers to diagnostic questions you'll face on rounds and exams. Prepared by residents and attending physicians at Massachusetts General Hospital, this portable, best-selling reference tackles the diagnosis and treatment of the most common disorders in cardiology, pulmonary medicine, gastroenterology, nephrology, hematology-oncology, infectious diseases, endocrinology, rheumatology, and neurology. Bulleted lists, tables, and algorithms focus on the information you need in order to make an accurate diagnosis and develop a treatment plan.
ISBN
9781-975142-377
Language
English
Material Type
Book
Call Number
WB 115 S23 2020

Copies

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Nature medicine

https://cwslc.andornot.com/en/permalink/catalog119779
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp50997&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=Nature+medicine
Alternate Title
Nat. Med.
Place of Publication
New York, NY
Publisher
Nature Publishing Group
Publication Date
1995 - Present.
ISSN
1078-8956
Language
English
Material Type
Serial
Frequency
Monthly
Holdings
CFRI/Study & Learning Commons - Print: v.1:1-v.11:7,10,12 (1995-2005); v.12:10 (2006); v.13:3 (2007); v.14:11+suppls. (2008).
Missing: v.1:2,5 (1995); v.4:1,2,6,8-12 (1998); v.5:1-6 (1999); v.6:8 (2000); v.11:8,9,11 (2005); v.12:1-11 (2006); v.13:1-2 (2007).
Online: 1995 to present.
Websites
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New England journal of medicine

https://cwslc.andornot.com/en/permalink/catalog119831
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp51617&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=I_M&C=0028-4793
Alternate Title
NEJM
Place of Publication
[Boston, MA]
Publisher
Massachusetts Medical Society
Publication Date
1990 - Present.
ISSN
0028-4793
Language
English
Material Type
Serial
Frequency
Weekly
Holdings
CFRI/Study & Learning Commons - Print: v.330:20-v.365:17 (1994-2011).
Missing: v.331:10,12,14,15,19-21 (1994); v.332:20 (1995); v.334:13 (1996); v.337:14 (1997); v.338:2,4,12,22 (1998); v.341:16 (1999); v.342:all (2000); v.343:3,4,6-13,15-17,19,21-22,24-26 (2000); v.344:19-21,23,26; v.345:4,5,7-9,11-13,16,17,20-23,26 (2001); v.346:6-9,14,15,18-20,26 (2002); v.349:5-8,11,12,17,18,24 (2003); v.350:21 (2004); v.353:6,8-13,20 (2005); v.354:7,10,16; v.355:15,18,23 (2006); v.356:2,3,20; v.357:23 (2007); v.358:22,23; v.359:16,18 (2008); v.360:23; v.361:1,9-12 (2009); v.362:4; v.363:21 (2010).
Online: 1990 to present.
Websites
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We Are All Perfectly Fine: A Memoir of Love, Medicine & Healing

https://cwslc.andornot.com/en/permalink/catalog124050
Horton, Jillian. Toronto: HarperCollins Publishers Ltd , 2021.
Material Type
Book
Call Number
REF MD 106 HOR 2021
Availability
1 copy, 1 available
Funny, fresh, and deeply affecting, We Are All Perfectly Fine is the story of a married mother of three on the brink of personal and professional collapse who attends rehab with a twist: a meditation retreat for burned-out doctors.; Jillian Horton, a general internist, has no idea what to expect du…
Author
Horton, Jillian
Place of Publication
Toronto
Publisher
HarperCollins Publishers Ltd
Publication Date
2021
Physical Description
290pp
Subjects
Mind and body
Meditation
Abstract
Funny, fresh, and deeply affecting, We Are All Perfectly Fine is the story of a married mother of three on the brink of personal and professional collapse who attends rehab with a twist: a meditation retreat for burned-out doctors.
Jillian Horton, a general internist, has no idea what to expect during her five-day retreat at Chapin Mill, a Zen centre in upstate New York. She just knows she desperately needs a break. At first she is deeply uncomfortable with the spartan accommodations, silent meals and scheduled bonding sessions. But as the group struggles through awkward first encounters and guided meditations, something remarkable happens: world-class surgeons, psychiatrists, pediatricians and general practitioners open up and share stories about their secret guilt and grief, as well as their deep-seated fear of falling short of the expectations that define them. Jillian realizes that her struggle with burnout is not so much personal as it is the result of a larger system failure, and that compartmentalizing your most difficult emotions?a coping strategy that is drilled into doctors?is not useful unless you face these emotions too.
Jillian Horton throws open a window onto the flawed system that shapes medical professionals, revealing the rarely acknowledged stresses that lead doctors to depression and suicide, and emphasizing the crucial role of compassion not only in treating others, but also in taking care of ourselves.
ISBN
9781-4434-61641
Language
English
Material Type
Book
Call Number
REF MD 106 HOR 2021

Copies

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Canadian journal of rural medicine: The official journal of the Society of Rural Physicians of Canada

https://cwslc.andornot.com/en/permalink/catalog114596
Website
PHSA Users:
http://web.a.ebscohost.com/pfi/detail/detail?vid=15&sid=80dd29ce-f1c9-480f-93d5-346abac169f7%40sessionmgr4009&hid=4106&bdata=JnNpdGU9cGZpLWxpdmU%3d#AN=edp15358&db=edspub
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=Canadian+journal+of+rural+medicine
Alternate Title
Canadian journal of rural medicine : the official journal of the Society of Rural Physicians of Canada = Journal canadien de la médecine rurale : le journal officiel de la Société de médecine rurale du Canada.
Corporate Author
Society of Rural Physicians of Canada
Place of Publication
[Ottawa, ON]
Publisher
Canadian Medical Association
Publication Date
1996 - Present
Notes
Articles in English; some are also in French.
ISSN
1203-7796
Language
English, French
Material Type
Serial
Frequency
Quarterly
Holdings
CFRI/Study & Learning Commons - Print:v.10:1-v.15:4 (2005-2010); v.16:3 (2011); v.17:1-2 (2012).
Missing: v.8:2-4 (2003); v.9:1-4 (2004); v.11:4 (2006); v.12:4 (2007); v.13:2 (2008).
Online: 1996 to present.
Websites
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BLS Basic life support: Provider manual

https://cwslc.andornot.com/en/permalink/catalog123201
American Heart Association, Heart & Stroke Foundation. [Ottawa, ON]: American Heart Association | Heart & Stroke Foundation , 2020.
Material Type
Book
Call Number
REF EB 270 AHA 2020
Availability
25 copies, 17 available
The Basic Life Support (BLS) for Healthcare Providers (HCP) is a classroom course that is designed to teach a variety of healthcare professionals how to recognize a number of life-threatening emergencies, how to provide CPR, how to use an AED and how to relieve choking in a safe, timely and effecti…
Website Notes
Click link to see Table of Contents
Corporate Author
American Heart Association
Heart & Stroke Foundation
Place of Publication
[Ottawa, ON]
Publisher
American Heart Association
Heart & Stroke Foundation
Publication Date
2020
Physical Description
Paperback: (112 p.: ill.).
Subject
Cardiopulmonary Resuscitation. CPR
First Aid
CPR
Certification
Abstract
The Basic Life Support (BLS) for Healthcare Providers (HCP) is a classroom course that is designed to teach a variety of healthcare professionals how to recognize a number of life-threatening emergencies, how to provide CPR, how to use an AED and how to relieve choking in a safe, timely and effective manner.
ISBN
9781988892603
Language
English
Material Type
Book
Call Number
REF EB 270 AHA 2020

Copies

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Neonatal Resuscitation Textbook (NRP): Provider Manual

https://cwslc.andornot.com/en/permalink/catalog123322
Weiner, Gary M., Zaichkin, Jeanette, Kattwinkel, John. Elk Grove Village, IL: American Academy of Pediatrics , 2021. 8th.
Material Type
Book
Call Number
REF EB 800 NEO 2021
Availability
71 copies, 45 available
The Neonatal Resuscitation Program (NRP) is an educational program jointly sponsored with the American Heart Association (AHA). The course conveys an evidence-based approach to care of the newborn at birth and facilitates effective team-based care for healthcare professionals who care for newborns …
Author
Weiner, Gary M.
Zaichkin, Jeanette
Kattwinkel, John
Edition
8th
Place of Publication
Elk Grove Village, IL
Publisher
American Academy of Pediatrics
Publication Date
2021
Physical Description
Paperback, 361 p., ill
Subject
Neonatal Assessment
First Aid
Nursing
Abstract
The Neonatal Resuscitation Program (NRP) is an educational program jointly sponsored with the American Heart Association (AHA). The course conveys an evidence-based approach to care of the newborn at birth and facilitates effective team-based care for healthcare professionals who care for newborns at the time of delivery.
New in the 8th edition:
Key Points at the beginning of each lesson.
Quick response (QR) codes that enable the reader to view short videos about the topic on their mobile device.
Lesson Review Questions grouped together at the end of each lesson.
Quality Improvement Opportunities and Frequently Asked Questions in each lesson.
New sections in Lesson 10 (Special Considerations) about resuscitation of the newborn with a myelomeningocele or an abdominal wall defect.
Three Supplemental Lessons (Improving Resuscitation Team Performance, Resuscitation Outside the Delivery Room, and Bringing Quality Improvement to Your Resuscitation Team) that all NRP users to enhance their resuscitation knowledge and performance.
ISBN
9781610025249
Language
English
Material Type
Book
Call Number
REF EB 800 NEO 2021

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The developing human: Clinical oriented embryology

https://cwslc.andornot.com/en/permalink/catalog123798
Moore, Keith L., Persaud, T.V.N. Philadelphia, PA: Saunders Elsevier , 2020. 11th Ed.
Material Type
Book
Call Number
REF AB 55 MOO 2020
Availability
1 copy, 1 available
Extensively revised toincorporate recent research and current clinical practice ,The Developing Human: Clinically Oriented Embryology, 11th Edition,covers all aspects of normal and abnormal embryonic and fetal development. In a clear, concise manner and lavishly illustrated throughout, this textboo…
Author
Moore, Keith L.
Persaud, T.V.N.
Edition
11th Ed.
Place of Publication
Philadelphia, PA
Publisher
Saunders Elsevier
Publication Date
2020
Physical Description
Softcover: 503 pages
Subject
Embryology
UBC MD Undergrad
Abstract
Extensively revised toincorporate recent research and current clinical practice ,The Developing Human: Clinically Oriented Embryology, 11th Edition,covers all aspects of normal and abnormal embryonic and fetal development. In a clear, concise manner and lavishly illustrated throughout, this textbook is designed to successfully meet the needs of medical and health sciences profession students, as well as those in graduate programs. It provides aneasy-to-digest, comprehensive review of what can be a complex and challenging subject .BONUS online features such asmultiple-choice questions and narrated animations further support student success.
ISBN
9780-323-611541
Language
English
Material Type
Book
Call Number
REF AB 55 MOO 2020

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Pediatric advanced life support (PALS): Provider manual

https://cwslc.andornot.com/en/permalink/catalog123835
Chameides, Leon (ed.), Samson, Ricardo A. (ed.), Schexnayder, Stephen M. (ed.), et all. [Canada]: American Heart Association , 2020.
Material Type
Book
Call Number
REF EB 100 PAL 2020
Availability
26 copies, 13 available
The Pediatric Advanced Life Support (PALS) Provider Course is designed for healthcare providers who initiate and direct basic through advanced life support. Course concepts are designed to be used throughout the stabilization and transport phases for both in-hospital and out-of-hospital pediatric e…
Author
Chameides, Leon (ed.)
Samson, Ricardo A. (ed.)
Schexnayder, Stephen M. (ed.), et all.
Corporate Author
Heart & Stroke Foundation
Place of Publication
[Canada]
Publisher
American Heart Association
Publication Date
2020
Physical Description
Paperback, 332 p.
Subject
First Aid
Certification
Abstract
The Pediatric Advanced Life Support (PALS) Provider Course is designed for healthcare providers who initiate and direct basic through advanced life support. Course concepts are designed to be used throughout the stabilization and transport phases for both in-hospital and out-of-hospital pediatric emergencies. This course aims to increase your skills in the evaluation and management of an infant or child with respiratory compromise, circulatory compromise, or cardiac arrest.
ISBN
9781-988892-900
Language
English
Material Type
Book
Call Number
REF EB 100 PAL 2020

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF On Loan, due Friday, April 14, 2023
Copy 2 BC Children's and Women's Study and Learning Commons REF On Loan, due Wednesday, May 29, 2024
Copy 3 BC Children's and Women's Study and Learning Commons REF On Loan, due Monday, June 12, 2023
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Advanced cardiovascular life support (ACLS): Provider manual

https://cwslc.andornot.com/en/permalink/catalog123903
Heart & Stroke Foundation. [United States of America]: American Heart Association , 2020.
Material Type
Book
Call Number
REF EB 100 ACL 2020
Availability
15 copies, 12 available
Advanced Cardiovascular Life Support (ACLS) courses provide critical training to Canadian healthcare professionals. The Heart & Stroke ACLS course has been updated to reflect new science from the 2020 Guidelines Update for CPR and Emergency Cardiovascular Care (2020 Guidelines for CPR and ECC).; AC…
Corporate Author
Heart & Stroke Foundation
Place of Publication
[United States of America]
Publisher
American Heart Association
Publication Date
2020
Physical Description
Paperback, 202 pp
Subject
First Aid
CPR
Certification
Abstract
Advanced Cardiovascular Life Support (ACLS) courses provide critical training to Canadian healthcare professionals. The Heart & Stroke ACLS course has been updated to reflect new science from the 2020 Guidelines Update for CPR and Emergency Cardiovascular Care (2020 Guidelines for CPR and ECC).
ACLS builds on the foundation of basic life support (BLS) skills, emphasizing the importance of continuous, high-quality CPR. This advanced course highlights the importance of preventing cardiac arrest, high-performance team dynamics and communication, systems of care, recognition and intervention of cardiopulmonary arrest, immediate post-cardiac arrest, acute dysrhythmia, stroke, and acute coronary syndromes.
The ACLS Provider Manual is designed for a single user and is required for all students taking an ACLS course. Students will use this book to progress through the course and as a reference tool before and after the classroom session.
ISBN
9781-988892-726
Language
English
Material Type
Book
Call Number
REF EB 100 ACL 2020

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF On Loan, due Monday, April 17, 2023
Copy 10 BC Children's and Women's Study and Learning Commons REF On Loan, due Monday, April 22, 2024
Copy 14 BC Children's and Women's Study and Learning Commons REF On Loan, due Thursday, July 13, 2023
Copy 2 BC Children's and Women's Study and Learning Commons REF Available
Copy 3 BC Children's and Women's Study and Learning Commons REF Available
Copy 4 BC Children's and Women's Study and Learning Commons REF Available
Copy 5 BC Children's and Women's Study and Learning Commons REF Available
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Copy 12 BC Children's and Women's Study and Learning Commons REF Available
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E-cadherin promotes tumorigenicity in human ovarian surface epithelium

https://cwslc.andornot.com/en/permalink/catalog113975
Ong, Aldrich Dixon. [Vancouver, BC?]: University of British Columbia , 1999.
Website
http://hdl.handle.net/2429/9760
Material Type
Thesis
Call Number
Thesis Shelf
Ovarian cancer is the most lethal gynecological cancer in the Western world, but comparatively little is known about its development. Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e. the mesothelium covering the ovary, but experimental evidence fo…
Website
http://hdl.handle.net/2429/9760
Author
Ong, Aldrich Dixon
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1999
Subject
Faculty of Medicine
Theses
Abstract
Ovarian cancer is the most lethal gynecological cancer in the Western world, but comparatively little is known about its development. Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e. the mesothelium covering the ovary, but experimental evidence for this origin has been lacking. Contrary to most epithelia where neoplastic progression is associated with loss of E-cadherin, this cell-cell adhesion molecule is sparse in normal human OSE but its expression increases in ovarian epithelial metaplasia and neoplasia.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Prostaglandin F[sub 2a]-mediated luteolytic and luteotrophic effects on the human granulosa-luteal cell

https://cwslc.andornot.com/en/permalink/catalog113976
Vaananen, Jeffrey Eric. [Vancouver, BC?]: University of British Columbia , 1997.
Website
http://hdl.handle.net/2429/6811
Material Type
Thesis
Call Number
Thesis Shelf
These studies examined the effects of prostaglandin-F[sub 2a] (PGF[sub 2a]) on progesterone and 178-estradiol (estradiol) production, as well as DNA and PGF[sub 2a]-receptor (PGF[sub 2a]-R) mRNA levels, in the human granulosa-luteal cell (GLC). Additionally, the interactions of PGF[sub 2a] with hum…
Website
http://hdl.handle.net/2429/6811
Author
Vaananen, Jeffrey Eric
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1997
Subject
Faculty of Medicine
Theses
Abstract
These studies examined the effects of prostaglandin-F[sub 2a] (PGF[sub 2a]) on progesterone and 178-estradiol (estradiol) production, as well as DNA and PGF[sub 2a]-receptor (PGF[sub 2a]-R) mRNA levels, in the human granulosa-luteal cell (GLC). Additionally, the interactions of PGF[sub 2a] with human chorionic gonadotrophin (hCG), gonadotrophin-releasing hormone (GnRH) and prostaglandin E₂ (PGE₂) were examined, with respect to progesterone and estradiol production.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Regulation of rat ovarian gonadotropin Releasing hormone receptor mRNA levels

https://cwslc.andornot.com/en/permalink/catalog113977
Vaananen, Celine Claire. [Vancouver, BC?]: University of British Columbia , 1997.
Website
http://hdl.handle.net/2429/6615
Material Type
Thesis
Call Number
Thesis Shelf
The studies undertaken herewithin sought to characterize the pattern of regulation of the gonadotrophin-releasing hormone receptor (GnRH-R) mRNA levels in the rat ovary. The demonstration of gonadotrophin-releasing hormone (GnRH) transcripts in steroidproducing and steroid-dependent tissues suggest…
Website
http://hdl.handle.net/2429/6615
Author
Vaananen, Celine Claire
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1997
Subject
Faculty of Medicine
Theses
Abstract
The studies undertaken herewithin sought to characterize the pattern of regulation of the gonadotrophin-releasing hormone receptor (GnRH-R) mRNA levels in the rat ovary. The demonstration of gonadotrophin-releasing hormone (GnRH) transcripts in steroidproducing and steroid-dependent tissues suggests that GnRH may be implicated in the modulation of steroid action in those target tissues. Expression of GnRH-R mRNA increases in gonadal tissues and the pituitary with age, supporting the concept of GnRH as a local regulator in the developing rat as well as in the adult.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Localization and regulation of mRNA transcripts encoding activin receptors in human placental trophoblast cells

https://cwslc.andornot.com/en/permalink/catalog113978
Chen, Victor. [Vancouver, BC?]: University of British Columbia , 1997.
Website
http://hdl.handle.net/2429/6315
Material Type
Thesis
Call Number
Thesis Shelf
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type…
Website
http://hdl.handle.net/2429/6315
Author
Chen, Victor
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1997
Subject
Faculty of Medicine
Theses
Abstract
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type II (II and ILB) receptors. The role of activin in the human placenta is not clearly understood. In this study, the detection of inlubin/activin subunit and ActRI mRNA were examined in first trimester cytotrophoblasts, term cytotrophoblasts, extravillous trophoblast (EVT) cells, immortalized extravillous trophoblast (LEVT) cells, JEG-3 cells, decidual tissue, and decidual cells.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Single cell studies of calcium as second messenger in human granulosa-lutein and embryonic kidney 293 cells

https://cwslc.andornot.com/en/permalink/catalog113979
Lee, Pearly S.N. [Vancouver, BC?]: University of British Columbia , 1999.
Website
http://hdl.handle.net/2429/10789
Material Type
Thesis
Call Number
Thesis Shelf
It is well established that LH action is mediated primarily by adenylate cyclase/cAMP. Conversely, the role of inositol phosphate/calcium in LH signalling has only recently been investigated. We examined the effects of gonadotrophins on intracellular calcium mobilisation in HEK293 cells transiently…
Website
http://hdl.handle.net/2429/10789
Author
Lee, Pearly S.N.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1999
Subject
Faculty of Medicine
Theses
Abstract
It is well established that LH action is mediated primarily by adenylate cyclase/cAMP. Conversely, the role of inositol phosphate/calcium in LH signalling has only recently been investigated. We examined the effects of gonadotrophins on intracellular calcium mobilisation in HEK293 cells transiently transfected with human wild type or chimeric gonadotrophs receptors (n=3400). Intracellular free calcium concentration was measured using fura-2 microspectrofluorimetric techniques. Human LH (2-4 μg/ml) arid CG (10 IU/ml) consistently evoked oscillatory calcium signals in HEK293 cells transfected with hLHr, whereas hFSH (2-4 μg/ml) failed to elicit any calcium responses.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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