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7 records – page 1 of 1.

Study of serum inhibin levels in two in-vitro fertilization protocols

https://cwslc.andornot.com/en/permalink/catalog113985
Kwong, Eugene Cheuk Kun. [Vancouver, BC?]: University of British Columbia , 1994.
Website
http://hdl.handle.net/2429/5375
Material Type
Thesis
Call Number
Thesis Shelf
In order to characterize and compare the pattern of inhibin production in the follicular phase between patients of the clomiphene citrate/human menopausal gonadotropin (hMG) and Buserelin/hMG protocols in in-vitro fertilization, serum inhibin levels from 20 patients in each protocol were measured. …
Website
http://hdl.handle.net/2429/5375
Author
Kwong, Eugene Cheuk Kun
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1994
Subject
Faculty of Medicine
Theses
Abstract
In order to characterize and compare the pattern of inhibin production in the follicular phase between patients of the clomiphene citrate/human menopausal gonadotropin (hMG) and Buserelin/hMG protocols in in-vitro fertilization, serum inhibin levels from 20 patients in each protocol were measured. The patients were matched for age and had tubal diseases only. It was hypothesized that the serum inhibin levels would be different in these two groups due to possible local actions of clomiphene citrate and Buserelin (a GnRH agonist) on the ovary.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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A morphological investigation of the effects of pregnant mare serum gonadotrophin on oocyte maturation, fertilization and embryonic development in rats

https://cwslc.andornot.com/en/permalink/catalog113990
Britton, Ann Patricia. [Vancouver, BC?]: University of British Columbia , 1991.
Website
http://hdl.handle.net/2429/30962
Material Type
Thesis
Call Number
Thesis Shelf
A delicate balance of steroid and gonadotrophic hormones is essential for intrafollicular oocyte maturation and successful fertilization and embryonic development. Previous studies have demonstrated that a superovulatory dose of pregnant mare serum gonadotrophin (PMSG) has excessive gonadotrophic a…
Website
http://hdl.handle.net/2429/30962
Author
Britton, Ann Patricia
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1991
Subject
Faculty of Medicine
Theses
Abstract
A delicate balance of steroid and gonadotrophic hormones is essential for intrafollicular oocyte maturation and successful fertilization and embryonic development. Previous studies have demonstrated that a superovulatory dose of pregnant mare serum gonadotrophin (PMSG) has excessive gonadotrophic activity and alters intrafol1icular steroid hormone levels. In a series of four experiments, the morphology of oocytes and embryos retrieved from immature rats, treated with either a low or high dose of PMSG, and mature, cycling rats was compared to determine whether a superovulatory dose of PMSG has an adverse effect on oocyte maturation and subsequent fertilization and embryonic development in immature rats. Morphological criteria for the assessment of intraoviductal oocyte aging were established in the first experiment.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Localization and regulation of mRNA transcripts encoding activin receptors in human placental trophoblast cells

https://cwslc.andornot.com/en/permalink/catalog113978
Chen, Victor. [Vancouver, BC?]: University of British Columbia , 1997.
Website
http://hdl.handle.net/2429/6315
Material Type
Thesis
Call Number
Thesis Shelf
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type…
Website
http://hdl.handle.net/2429/6315
Author
Chen, Victor
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1997
Subject
Faculty of Medicine
Theses
Abstract
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type II (II and ILB) receptors. The role of activin in the human placenta is not clearly understood. In this study, the detection of inlubin/activin subunit and ActRI mRNA were examined in first trimester cytotrophoblasts, term cytotrophoblasts, extravillous trophoblast (EVT) cells, immortalized extravillous trophoblast (LEVT) cells, JEG-3 cells, decidual tissue, and decidual cells.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Superovulation and chromosomal aberrations

https://cwslc.andornot.com/en/permalink/catalog113983
Ma, Sai. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7516
Material Type
Thesis
Call Number
Thesis Shelf
In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fai…
Website
http://hdl.handle.net/2429/7516
Author
Ma, Sai
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fail to achieve or sustain implantation. The failure of implantation has raised questions about the possible detrimental effect of superovulation on chromosomal complements. In this study, the hypothesis that chromosomal aberrations exist in mouse preimplantation embryos and human unfertilized oocytes after superovulation, was tested. The incidence of aneuploidy in spontaneously ovulated group (5.6%) was similar to that reported by others.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Studies of a sperm antigen recognized by two monoclonal antibodies

https://cwslc.andornot.com/en/permalink/catalog113986
McChesney, Patricia. [Vancouver, BC?]: University of British Columbia , 1994.
Website
http://hdl.handle.net/2429/5455
Material Type
Thesis
Call Number
Thesis Shelf
In order to characterize and compare the pattern of inhibin production in the follicular phase between patients of the clomiphene citrate/human menopausal gonadotropin (hMG) and Buserelin/hMG protocols in in-vitro fertilization, serum inhibin levels from 20 patients in each protocol were measured. …
Website
http://hdl.handle.net/2429/5455
Author
McChesney, Patricia
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1994
Subject
Faculty of Medicine
Theses
Abstract
In order to characterize and compare the pattern of inhibin production in the follicular phase between patients of the clomiphene citrate/human menopausal gonadotropin (hMG) and Buserelin/hMG protocols in in-vitro fertilization, serum inhibin levels from 20 patients in each protocol were measured. The patients were matched for age and had tubal diseases only. It was hypothesized that the serum inhibin levels would be different in these two groups due to possible local actions of clomiphene citrate and Buserelin (a GnRH agonist) on the ovary.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Studies of a sperm acrosomal antigen recognized by HS-63 monoclonal antibody

https://cwslc.andornot.com/en/permalink/catalog113989
Liu, Ming-Sun. [Vancouver, BC?]: University of British Columbia , 1991.
Website
http://hdl.handle.net/2429/30996
Material Type
Thesis
Call Number
Thesis Shelf
A sperm specific and species conserved monoclonal antibody (HS-63) was shown to inhibit in vitro fertilization of mouse oocytes and human sperm penetration to zona-free hamster ova. The sperm antigen (SA-63) which reacts with HS-63 was found to be localized on the sperm acrosome. Following sperm ca…
Website
http://hdl.handle.net/2429/30996
Author
Liu, Ming-Sun
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1991
Subject
Faculty of Medicine
Theses
Abstract
A sperm specific and species conserved monoclonal antibody (HS-63) was shown to inhibit in vitro fertilization of mouse oocytes and human sperm penetration to zona-free hamster ova. The sperm antigen (SA-63) which reacts with HS-63 was found to be localized on the sperm acrosome. Following sperm capacitation, this antigen becomes exposed and is shed after the acrosome reaction. SA-63 may be involved in the sperm acrosome reaction during the initial fertilization process.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Amyloid: The International Journal of Experimental & Clinical Investigation: the official journal of the International Society of Amyloidosis

https://cwslc.andornot.com/en/permalink/catalog119862
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp123865&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=I_M&C=1350-6129
Continues / Continued By
Amyloid: The Journal of Protein Folding Disorders
Alternate Title
Amyloid
Place of Publication
Rochester, Mn.
Publisher
The International Society of Amyloidosis
Publication Date
1994 ? Present
ISSN
1350-612
Language
English
Material Type
Serial
Frequency
Irregular or Other
Holdings
CFRI/Study & Learning Commons - Print: v.5:1-v.8:4 +suppls. (1998-2001).
Online: 2003 to present.
Websites
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7 records – page 1 of 1.