Search Results - C&W Library Catalogue

Revise Search

Material Type

Language

Date

Author

Subject

Online Media Type

6 records – page 1 of 1.

Prev Next

Ligand-independent activation of steroid hormone receptors by gonadotropin-releasing hormone

https://cwslc.andornot.com/en/permalink/catalog113952

Chen, Junling. [Vancouver, BC?]: University of British Columbia , 2010.

Website: http://hdl.handle.net/2429/34980

Material Type: Thesis

Call Number: Thesis Shelf

Nuclear receptors including estrogen receptors (ERs) and progesterone receptors (PRs) are activated by their ligands as well as by signaling pathways in response to peptide hormones and growth factors. In gonadotrophs, gonadotropin releasing hormones (GnRHs) act via the GnRH receptor (GnRHR). Both …

1 website

Website: http://hdl.handle.net/2429/34980

Author: Chen, Junling

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 2010

Subject: Faculty of Medicine; Theses

Abstract: Nuclear receptors including estrogen receptors (ERs) and progesterone receptors (PRs) are activated by their ligands as well as by signaling pathways in response to peptide hormones and growth factors. In gonadotrophs, gonadotropin releasing hormones (GnRHs) act via the GnRH receptor (GnRHR). Both GnRH-I and GnRH-II activate an estrogen response element (ERE)-driven luciferase reporter gene in LβT2 mouse pituitary cells, and GnRH-I is more potent in this regard.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

Websites

http://hdl.handle.net/2429/34980

Single cell studies of calcium as second messenger in human granulosa-lutein and embryonic kidney 293 cells

https://cwslc.andornot.com/en/permalink/catalog113979

Lee, Pearly S.N. [Vancouver, BC?]: University of British Columbia , 1999.

Website: http://hdl.handle.net/2429/10789

Material Type: Thesis

Call Number: Thesis Shelf

It is well established that LH action is mediated primarily by adenylate cyclase/cAMP. Conversely, the role of inositol phosphate/calcium in LH signalling has only recently been investigated. We examined the effects of gonadotrophins on intracellular calcium mobilisation in HEK293 cells transiently…

1 website

Website: http://hdl.handle.net/2429/10789

Author: Lee, Pearly S.N.

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 1999

Subject: Faculty of Medicine; Theses

Abstract: It is well established that LH action is mediated primarily by adenylate cyclase/cAMP. Conversely, the role of inositol phosphate/calcium in LH signalling has only recently been investigated. We examined the effects of gonadotrophins on intracellular calcium mobilisation in HEK293 cells transiently transfected with human wild type or chimeric gonadotrophs receptors (n=3400). Intracellular free calcium concentration was measured using fura-2 microspectrofluorimetric techniques. Human LH (2-4 μg/ml) arid CG (10 IU/ml) consistently evoked oscillatory calcium signals in HEK293 cells transfected with hLHr, whereas hFSH (2-4 μg/ml) failed to elicit any calcium responses.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

Websites

http://hdl.handle.net/2429/10789

Studies of a sperm acrosomal antigen recognized by HS-63 monoclonal antibody

https://cwslc.andornot.com/en/permalink/catalog113989

Liu, Ming-Sun. [Vancouver, BC?]: University of British Columbia , 1991.

Website: http://hdl.handle.net/2429/30996

Material Type: Thesis

Call Number: Thesis Shelf

A sperm specific and species conserved monoclonal antibody (HS-63) was shown to inhibit in vitro fertilization of mouse oocytes and human sperm penetration to zona-free hamster ova. The sperm antigen (SA-63) which reacts with HS-63 was found to be localized on the sperm acrosome. Following sperm ca…

1 website

Website: http://hdl.handle.net/2429/30996

Author: Liu, Ming-Sun

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 1991

Subject: Faculty of Medicine; Theses

Abstract: A sperm specific and species conserved monoclonal antibody (HS-63) was shown to inhibit in vitro fertilization of mouse oocytes and human sperm penetration to zona-free hamster ova. The sperm antigen (SA-63) which reacts with HS-63 was found to be localized on the sperm acrosome. Following sperm capacitation, this antigen becomes exposed and is shed after the acrosome reaction. SA-63 may be involved in the sperm acrosome reaction during the initial fertilization process.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

Websites

http://hdl.handle.net/2429/30996

Studies of a sperm antigen recognized by two monoclonal antibodies

https://cwslc.andornot.com/en/permalink/catalog113986

McChesney, Patricia. [Vancouver, BC?]: University of British Columbia , 1994.

Website: http://hdl.handle.net/2429/5455

Material Type: Thesis

Call Number: Thesis Shelf

In order to characterize and compare the pattern of inhibin production in the follicular phase between patients of the clomiphene citrate/human menopausal gonadotropin (hMG) and Buserelin/hMG protocols in in-vitro fertilization, serum inhibin levels from 20 patients in each protocol were measured. …

1 website

Website: http://hdl.handle.net/2429/5455

Author: McChesney, Patricia

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 1994

Subject: Faculty of Medicine; Theses

Abstract: In order to characterize and compare the pattern of inhibin production in the follicular phase between patients of the clomiphene citrate/human menopausal gonadotropin (hMG) and Buserelin/hMG protocols in in-vitro fertilization, serum inhibin levels from 20 patients in each protocol were measured. The patients were matched for age and had tubal diseases only. It was hypothesized that the serum inhibin levels would be different in these two groups due to possible local actions of clomiphene citrate and Buserelin (a GnRH agonist) on the ovary.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

Websites

http://hdl.handle.net/2429/5455

Studies of sperm antigens using specific monoclonal antibodies

https://cwslc.andornot.com/en/permalink/catalog113995

Sun, Ping. [Vancouver, BC?]: University of British Columbia , 1987.

Website: http://hdl.handle.net/2429/28405

Material Type: Thesis

Call Number: Thesis Shelf

This thesis work is focused on studies of sperm antigen: its purification and antifertility effect, its "internal image" by use of anti-idiotypic antibodies, and its capacity to induce antibodies of IgA class. Mouse sperm acrosomal antigens that react with a monoclonal antibody generated against mo…

1 website

Website: http://hdl.handle.net/2429/28405

Author: Sun, Ping

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 1987

Subject: Faculty of Medicine; Theses

Abstract: This thesis work is focused on studies of sperm antigen: its purification and antifertility effect, its "internal image" by use of anti-idiotypic antibodies, and its capacity to induce antibodies of IgA class. Mouse sperm acrosomal antigens that react with a monoclonal antibody generated against mouse spermatozoa, MS 207, were purified by immunoaffinity chromatography from soluble fraction of mouse testis homogenates.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

Websites

http://hdl.handle.net/2429/28405

Study of serum inhibin levels in two in-vitro fertilization protocols

https://cwslc.andornot.com/en/permalink/catalog113985

Kwong, Eugene Cheuk Kun. [Vancouver, BC?]: University of British Columbia , 1994.

Website: http://hdl.handle.net/2429/5375

Material Type: Thesis

Call Number: Thesis Shelf

In order to characterize and compare the pattern of inhibin production in the follicular phase between patients of the clomiphene citrate/human menopausal gonadotropin (hMG) and Buserelin/hMG protocols in in-vitro fertilization, serum inhibin levels from 20 patients in each protocol were measured. …

1 website

Website: http://hdl.handle.net/2429/5375

Author: Kwong, Eugene Cheuk Kun

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 1994

Subject: Faculty of Medicine; Theses

Abstract: In order to characterize and compare the pattern of inhibin production in the follicular phase between patients of the clomiphene citrate/human menopausal gonadotropin (hMG) and Buserelin/hMG protocols in in-vitro fertilization, serum inhibin levels from 20 patients in each protocol were measured. The patients were matched for age and had tubal diseases only. It was hypothesized that the serum inhibin levels would be different in these two groups due to possible local actions of clomiphene citrate and Buserelin (a GnRH agonist) on the ovary.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

Websites

http://hdl.handle.net/2429/5375

6 records – page 1 of 1.

Prev Next