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Action of luteinizing hormone-releasing hormone in rat ovarian cells : hormone production and signal transduction

https://cwslc.andornot.com/en/permalink/catalog113996

Wang, Jian. [Vancouver, BC?]: University of British Columbia , 1989.

Website: http://hdl.handle.net/2429/29313

Material Type: Thesis

Call Number: Thesis Shelf

The present study was conducted to investigate the hypothesis that membrane phosphoinositide breakdown may participate in the actions of luteinizing hormone-releasing hormone (LHRH) on hormone production in the rat ovary. In granulosa cells prelabeled with [³H]-arachidonic acid or [³H]-inositol, tr…

1 website

Website: http://hdl.handle.net/2429/29313

Author: Wang, Jian

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 1989

Subject: Faculty of Medicine; Theses

Abstract: The present study was conducted to investigate the hypothesis that membrane phosphoinositide breakdown may participate in the actions of luteinizing hormone-releasing hormone (LHRH) on hormone production in the rat ovary. In granulosa cells prelabeled with [³H]-arachidonic acid or [³H]-inositol, treatment with LHRH increased the accumulation of radiolabeled inositol lipids, diacylglycerol and free arachidonic acid, but luteinizing hormone (LH) or cholera toxin did not exert the same effect. Activation of protein kinase C by the phorbol ester, 12-0-tetradecanoyl phorbol-13-acetate (TPA) had a stimulatory action on membrane phosphoinositide breakdown.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

Websites

http://hdl.handle.net/2429/29313

Biotechniques: The International Journal of Life Science Methods

https://cwslc.andornot.com/en/permalink/catalog114500

New York, NY: Informa BioSciences , 1983 to present.

Website: UBC Users:; http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=bio+techniques

Material Type: Serial

2 websites

Website: UBC Users:; http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=bio+techniques

Alternate Title: Bio techniques

Place of Publication: New York, NY

Publisher: Informa BioSciences

Publication Date: 1983 to present

ISSN: 0736-6205

Language: English

Material Type: Serial

Frequency: Monthly

Holdings: CFRI/Study & Learning Commons - Print: v.16:1-v.47:5+suppl. (1994-2009); Missing: v.19:1 (1995); v.21:4 (1996); v.29:1 (2000); v.31:5 (2001); v.32:1,4 (2002); v.41:4-5 (2006); v.42:3,5 (2007); v. 43:2 (2007); v.46:1,3-5 (2009); v.47:6 (2009).; Online: 1996-

Websites

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=bio+techniques

Effects and mechanisms of growth differentiation factor 9 on activin A-regulated inhibin B and progesterone production in human granulosa cells

https://cwslc.andornot.com/en/permalink/catalog113951

Shi, Fengtao. [Vancouver, BC?]: University of British Columbia , 2010.

Website: http://hdl.handle.net/2429/28961

Material Type: Thesis

Call Number: Thesis Shelf

Activin A (homodimer of inhibin βA-subunit) is known to increase inhibin βB-subunit and inhibin B (heterodimer of inhibin α- and βB-subunit) levels and decrease progesterone accumulation in human granulosa cells. Growth differentiation factor 9 (GDF9) is a potent paracrine regul…

1 website

Website: http://hdl.handle.net/2429/28961

Author: Shi, Fengtao

Place of Publication: [Vancouver, BC?]

Publisher: University of British Columbia

Publication Date: 2010

Subject: Faculty of Medicine; Theses

Abstract: Activin A (homodimer of inhibin βA-subunit) is known to increase inhibin βB-subunit and inhibin B (heterodimer of inhibin α- and βB-subunit) levels and decrease progesterone accumulation in human granulosa cells. Growth differentiation factor 9 (GDF9) is a potent paracrine regulator of ovarian function, but its overall effects, particularly relating to activin A actions, are unknown. We examined the potential crosstalk between activin A and GDF9 in primary cultures of human granulosa-lutein (hGL) cells. Pretreatment of hGL cells with GDF9 for 24 h resulted in an increased expression of activin receptors and Smad2/3, and decreased inhibitory Smad7 activity. These effects were attenuated by BMP type II receptor ectodomain (BMPR2 ECD), a GDF9 antagonist.

Language: English

Material Type: Thesis

Call Number: Thesis Shelf

Websites

http://hdl.handle.net/2429/28961

Nature methods

https://cwslc.andornot.com/en/permalink/catalog119780

New York, NY: Nature Publishing Group , 2004 - Present.

Website: PHSA Users:; Not available online:; UBC Users:; http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=nature+methods

Material Type: Serial

4 websites

Website: PHSA Users:; Not available online:; UBC Users:; http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=nature+methods

Alternate Title: Nat. Methods

Place of Publication: New York, NY

Publisher: Nature Publishing Group

Publication Date: 2004 - Present.

ISSN: 1548-7091

Language: English

Material Type: Serial

Frequency: Monthly

Holdings: CFRI/Study & Learning Commons - Print: v.1:1-v.3:6 (2004-2006); v.6:1 (2009).; Online: 2004 to present.

Websites

PHSA Users:

Not available online:

UBC Users:

http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=nature+methods