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20 records – page 1 of 1.

American journal of human genetics

https://cwslc.andornot.com/en/permalink/catalog114382

Atlas of human cross-sectional anatomy: With CT and MR images

https://cwslc.andornot.com/en/permalink/catalog112634
Cahill, Donald R., Orland, Matthew J., Miller, Gary M. [Toronto, ON]: Wiley-Liss , 1995. 3rd ed.
Material Type
Book
Call Number
REF AC 205 CAH 1995
Availability
1 copy, 1 available
This atlas provides detailed illustrations of anatomical cross-sections - meticulously drawn and labeled - that are matched with high-quality CT or MR images or actual photographs of cadaver sections. Orientation diagrams appear on the corner of every page and show precisely where the slice was tak…
Author
Cahill, Donald R.
Orland, Matthew J.
Miller, Gary M.
Edition
3rd ed.
Place of Publication
[Toronto, ON]
Publisher
Wiley-Liss
Publication Date
1995
Physical Description
Hardcover: 300 p.
Subject
Anatomy-Atlases. Pictorial Works
Abstract
This atlas provides detailed illustrations of anatomical cross-sections - meticulously drawn and labeled - that are matched with high-quality CT or MR images or actual photographs of cadaver sections. Orientation diagrams appear on the corner of every page and show precisely where the slice was taken as well as the direction from which the slice is being viewed.
ISBN
9780471591658
Language
English
Material Type
Book
Call Number
REF AC 205 CAH 1995

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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ATTENDING: Medicine, Mindfulness & Humanity

https://cwslc.andornot.com/en/permalink/catalog124049
Epstein, Ronald. New York: Scribner , 2017.
Material Type
Book
Call Number
REF MD 106 EPS 2017
Availability
1 copy, 0 available
The first book for the general public about the importance of mindfulness in medical practice, Attending is a groundbreaking, intimate exploration of how doctors approach their work with patients. From his early days as a Harvard Medical School student, Epstein saw what made good doctors great?more…
Author
Epstein, Ronald
Place of Publication
New York
Publisher
Scribner
Publication Date
2017
Physical Description
292pp
Subjects
Mind and body
Meditation
Abstract
The first book for the general public about the importance of mindfulness in medical practice, Attending is a groundbreaking, intimate exploration of how doctors approach their work with patients. From his early days as a Harvard Medical School student, Epstein saw what made good doctors great?more accurate diagnoses, fewer errors, and stronger connections with their patients. This made a lasting impression on him and set the stage for his life?s work?identifying the qualities and habits that distinguish master clinicians from those who are merely competent. The secret, he learned, was mindfulness.
ISBN
978-15011-21722
Language
English
Material Type
Book
Call Number
REF MD 106 EPS 2017

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF On Loan, due Wednesday, June 21, 2023
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Beyond self-care for helping professionals : the expressive therapies continuum and the life enrichment model

https://cwslc.andornot.com/en/permalink/catalog124763
Hinz, Lisa D. New York, NY: Routledge , 2019.
Material Type
Book
Call Number
AA 74 HIN 2019
Availability
2 copies, 2 available
Beyond Self-Care for Helping Professionals is an innovative guide to professional self-care focused not just on avoiding the consequences of failing to take care of oneself, but on optimal health and positive psychology. This new volume builds upon the Expressive Therapies Continuum to introduce th…
  1 image     1 document  
Author
Hinz, Lisa D.
Place of Publication
New York, NY
Publisher
Routledge
Publication Date
2019
Physical Description
134p
Subjects
Self Care
Caregivers
Healthy Lifestyle
Abstract
Beyond Self-Care for Helping Professionals is an innovative guide to professional self-care focused not just on avoiding the consequences of failing to take care of oneself, but on optimal health and positive psychology. This new volume builds upon the Expressive Therapies Continuum to introduce the Life Enrichment Model, a strengths-based model that encourages mindful participation in a broad array of enriching experiences. By enabling therapists and other Helping Professionals to develop a rich emotional, intellectual, and creative foundation to their lives and clinical practices, this guide sets a new standard for self-care in the helping professions.
ISBN
9781138231016
Language
English
Material Type
Book
Call Number
AA 74 HIN 2019

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
Copy 2 BC Children's and Women's Study and Learning Commons REF Available
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Documents

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Challenging genetic determinism: New perspectives on the gene in its multiple environments

https://cwslc.andornot.com/en/permalink/catalog113270
Maheu, Louis, Macdonal, Roderick A. (Eds). Kingston, ON: McGill-Queen's University Press , 2011.
Material Type
Book
Call Number
REF GI 200 MAC 2011
Availability
2 copies, 2 available
Advances in genetic research have captured the attention of the media and the public through reports about genetically caused diseases and behaviours. However, all too often the coverage of scientists' innovations has implied that genetic factors alone are responsible for effects ranging from perso…
Author
Maheu, Louis
Macdonal, Roderick A. (Eds)
Place of Publication
Kingston, ON
Publisher
McGill-Queen's University Press
Publication Date
2011
Physical Description
319 pages
Subject
Personality
Genetics
UBC MD Undergrad
Abstract
Advances in genetic research have captured the attention of the media and the public through reports about genetically caused diseases and behaviours. However, all too often the coverage of scientists' innovations has implied that genetic factors alone are responsible for effects ranging from personality and sexual preferences to morbid obesity and intellectual disabilities. Challenging Genetic Determinism argues that hypotheses cannot be based solely on genetic factors but must take into account the context in which these factors occur.
ISBN
978-0773538139
Language
English
Material Type
Book
Call Number
REF GI 200 MAC 2011

Copies

Copy 2 BC Children's and Women's Study and Learning Commons REF Available
Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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The characterization of ADAMTS-12 in the regulation of human trophoblast invasion in vitro

https://cwslc.andornot.com/en/permalink/catalog113949
Zou, Junxuan. [Vancouver, BC?]: University of British Columbia , 2010.
Website
http://hdl.handle.net/2429/29783
Material Type
Thesis
Call Number
Thesis Shelf
The distintegrin-like and metalloproteinase with thrombospondin repeats (ADAMTS) are members of a gene family of secreted, multidomain and multifunctional proteinases that are able to proteolytically degrade a diverse array of cellular, extracellular and extracellular matrix (ECM) substrates. We ex…
Website
http://hdl.handle.net/2429/29783
Author
Zou, Junxuan
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2010
Subject
Faculty of Medicine
Theses
Abstract
The distintegrin-like and metalloproteinase with thrombospondin repeats (ADAMTS) are members of a gene family of secreted, multidomain and multifunctional proteinases that are able to proteolytically degrade a diverse array of cellular, extracellular and extracellular matrix (ECM) substrates. We examined the presence of ADAMTS in first trimester human placenta and only ADAMTS-12 was present in cultures of invasive extravillous cytotrophoblast (EVT) at significantly higher levels than in poorly invasive JEG-3 chorocarcinoma cells. Immunohistochemistry staining of chorionic villi derived from first trimester human placenta demonstrated that ADAMTS-12 was intensively immunolocalized in the cytotrophoblast layer but weakly immunolocalized in the poorly-invasive syncytial trophoblast layer.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Characterization of the human gonadotropin-releasing hormone receptor gene at the molecular level

https://cwslc.andornot.com/en/permalink/catalog113982
Fan, Nancy C. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7255
Material Type
Thesis
Call Number
Thesis Shelf
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling sti…
Website
http://hdl.handle.net/2429/7255
Author
Fan, Nancy C.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling stimulates the synthesis and release of both luteinizing hormone and follicle stimulating hormone from the anterior pituitary. In addition, GnRH - GnRH receptor binding acts locally to regulate human chorionic gonadotropin secretion in the placenta and steroidogenesis in the ovary. The objective of this thesis was to isolate and characterize the gene for the GnRH receptor in human.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Conn's current therapy 2013

https://cwslc.andornot.com/en/permalink/catalog112712
Bope, Edward T., Kellerman, Rick D. Philadelphia, PA: Elsevier Saunders , 2013.
Material Type
Book
Call Number
REF FA 140 BOP 2013
Availability
1 copy, 1 available
This text is designed to provide busy medical practitioners with quick, reliable treatment protocols for the most common complaints and diagnoses.
Author
Bope, Edward T.
Kellerman, Rick D.
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Publication Date
2013
Physical Description
Hardcover: 1236 p.
Subject
Diagnostic Tests/Procedures. Physical Diagnosis
Symptoms
UBC MD Undergrad
Abstract
This text is designed to provide busy medical practitioners with quick, reliable treatment protocols for the most common complaints and diagnoses.
ISBN
9781455702954
Language
English
Material Type
Book
Call Number
REF FA 140 BOP 2013

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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Crisis Management in Acute Care Settings: Human Factors, Team Psychology, and Patient Safety in a High Stakes Environment

https://cwslc.andornot.com/en/permalink/catalog114233
St. Pierre, Michael, Buerschaper, Cornelius, Simon, Robert. Berlin, Germany: Springer-Verlag , 2011. 2nd Ed.
Material Type
Book
Call Number
REF EB 800 STP 2011
Availability
1 copy, 1 available
Critical situations in acute and emergency care are one of the great clinical challenges because of the uncertainty, high stakes, time pressure, and stress that are involved. This book provides a comprehensive outline of all the human factors issues relevant to patient safety during acute care. Fol…
Author
St. Pierre, Michael
Buerschaper, Cornelius
Simon, Robert
Edition
2nd Ed.
Place of Publication
Berlin, Germany
Publisher
Springer-Verlag
Publication Date
2011
Physical Description
Hardcover: 346 pages
Subject
Emergency Care Services. Emergency Room. ER
Emergency Medicine
Safety
Abstract
Critical situations in acute and emergency care are one of the great clinical challenges because of the uncertainty, high stakes, time pressure, and stress that are involved. This book provides a comprehensive outline of all the human factors issues relevant to patient safety during acute care. Following an initial section discussing the basic principles of human behavior and decision making, the various influences on safe patient care are discussed in depth. These are divided into three interacting groups: individual factors, team factors, and organizational factors. Relevant psychological theories are carefully examined, and case studies and descriptions of proven strategies help to ground these theories in daily practice. This newly revised edition will help both physicians and non-physicians to better understand the principles of human behavior and decision making in critical situations and thus to provide safer treatment.
ISBN
9783642196997
Language
English
Material Type
Book
Call Number
REF EB 800 STP 2011

Copies

Copy 1 BC Children's and Women's Study and Learning Commons Available
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The developing human: Clinical oriented embryology

https://cwslc.andornot.com/en/permalink/catalog112676
Moore, Keith L., Persaud, T.V.N. Philadelphia, PA: Saunders Elsevier , 2008. 8th Ed.
Material Type
Book
Call Number
REF AB 55 MOO 2008
Availability
1 copy, 1 available
This text examines all aspects of human development, emphasizing both basic concepts and relevant clinical problems. The book presents a week-by-week and stage-by-stage view of how fetal organs and systems develop, why and when birth defects occur, and what roles the placenta and fetal membranes pl…
Author
Moore, Keith L.
Persaud, T.V.N.
Edition
8th Ed.
Place of Publication
Philadelphia, PA
Publisher
Saunders Elsevier
Publication Date
2008
Physical Description
Softcover: 522 pages
Subject
Embryology
UBC MD Undergrad
Abstract
This text examines all aspects of human development, emphasizing both basic concepts and relevant clinical problems. The book presents a week-by-week and stage-by-stage view of how fetal organs and systems develop, why and when birth defects occur, and what roles the placenta and fetal membranes play in development.
ISBN
9781416037064
Language
English
Material Type
Book
Call Number
REF AB 55 MOO 2008

Copies

Copy 1 BC Children's and Women's Study and Learning Commons MISSING Available
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The developing human: Clinical oriented embryology

https://cwslc.andornot.com/en/permalink/catalog123798
Moore, Keith L., Persaud, T.V.N. Philadelphia, PA: Saunders Elsevier , 2020. 11th Ed.
Material Type
Book
Call Number
REF AB 55 MOO 2020
Availability
1 copy, 1 available
Extensively revised toincorporate recent research and current clinical practice ,The Developing Human: Clinically Oriented Embryology, 11th Edition,covers all aspects of normal and abnormal embryonic and fetal development. In a clear, concise manner and lavishly illustrated throughout, this textboo…
Author
Moore, Keith L.
Persaud, T.V.N.
Edition
11th Ed.
Place of Publication
Philadelphia, PA
Publisher
Saunders Elsevier
Publication Date
2020
Physical Description
Softcover: 503 pages
Subject
Embryology
UBC MD Undergrad
Abstract
Extensively revised toincorporate recent research and current clinical practice ,The Developing Human: Clinically Oriented Embryology, 11th Edition,covers all aspects of normal and abnormal embryonic and fetal development. In a clear, concise manner and lavishly illustrated throughout, this textbook is designed to successfully meet the needs of medical and health sciences profession students, as well as those in graduate programs. It provides aneasy-to-digest, comprehensive review of what can be a complex and challenging subject .BONUS online features such asmultiple-choice questions and narrated animations further support student success.
ISBN
9780-323-611541
Language
English
Material Type
Book
Call Number
REF AB 55 MOO 2020

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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DNA methylation at imprinted and non-imprinted genes in the sperm of men affected by severe male factor infertility

https://cwslc.andornot.com/en/permalink/catalog113950
Minor, Agata. [Vancouver, BC?]: University of British Columbia , 2010.
Website
http://hdl.handle.net/2429/29282
Material Type
Thesis
Call Number
Thesis Shelf
Abnormal DNA methylation at imprinted and non-imprinted genes has been associated with spermatogenesis failure. However, little information is available regarding DNA methylation at those genes in men affected by severe male factor infertility. We hypothesized a higher incidence of aberrant DNA met…
Website
http://hdl.handle.net/2429/29282
Author
Minor, Agata
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2010
Subject
Faculty of Medicine
Theses
Abstract
Abnormal DNA methylation at imprinted and non-imprinted genes has been associated with spermatogenesis failure. However, little information is available regarding DNA methylation at those genes in men affected by severe male factor infertility. We hypothesized a higher incidence of aberrant DNA methylation would be present in the ejaculate and testicular sperm of men affected by severe male factor infertility compared to that in fertile control men. Furthermore, we hypothesized abnormal DNA methylation would also affect non-imprinted genes in the sperm of men affected by severe oligozoospermia.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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E-cadherin promotes tumorigenicity in human ovarian surface epithelium

https://cwslc.andornot.com/en/permalink/catalog113975
Ong, Aldrich Dixon. [Vancouver, BC?]: University of British Columbia , 1999.
Website
http://hdl.handle.net/2429/9760
Material Type
Thesis
Call Number
Thesis Shelf
Ovarian cancer is the most lethal gynecological cancer in the Western world, but comparatively little is known about its development. Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e. the mesothelium covering the ovary, but experimental evidence fo…
Website
http://hdl.handle.net/2429/9760
Author
Ong, Aldrich Dixon
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1999
Subject
Faculty of Medicine
Theses
Abstract
Ovarian cancer is the most lethal gynecological cancer in the Western world, but comparatively little is known about its development. Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e. the mesothelium covering the ovary, but experimental evidence for this origin has been lacking. Contrary to most epithelia where neoplastic progression is associated with loss of E-cadherin, this cell-cell adhesion molecule is sparse in normal human OSE but its expression increases in ovarian epithelial metaplasia and neoplasia.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Effects and mechanisms of growth differentiation factor 9 on activin A-regulated inhibin B and progesterone production in human granulosa cells

https://cwslc.andornot.com/en/permalink/catalog113951
Shi, Fengtao. [Vancouver, BC?]: University of British Columbia , 2010.
Website
http://hdl.handle.net/2429/28961
Material Type
Thesis
Call Number
Thesis Shelf
Activin A (homodimer of inhibin βA-subunit) is known to increase inhibin βB-subunit and inhibin B (heterodimer of inhibin α- and βB-subunit) levels and decrease progesterone accumulation in human granulosa cells. Growth differentiation factor 9 (GDF9) is a potent paracrine regul…
Website
http://hdl.handle.net/2429/28961
Author
Shi, Fengtao
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2010
Subject
Faculty of Medicine
Theses
Abstract
Activin A (homodimer of inhibin βA-subunit) is known to increase inhibin βB-subunit and inhibin B (heterodimer of inhibin α- and βB-subunit) levels and decrease progesterone accumulation in human granulosa cells. Growth differentiation factor 9 (GDF9) is a potent paracrine regulator of ovarian function, but its overall effects, particularly relating to activin A actions, are unknown. We examined the potential crosstalk between activin A and GDF9 in primary cultures of human granulosa-lutein (hGL) cells. Pretreatment of hGL cells with GDF9 for 24 h resulted in an increased expression of activin receptors and Smad2/3, and decreased inhibitory Smad7 activity. These effects were attenuated by BMP type II receptor ectodomain (BMPR2 ECD), a GDF9 antagonist.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Expression and function of HOXA genes in the normal ovary and ovarian carcinoma

https://cwslc.andornot.com/en/permalink/catalog113963
Ota, Takayo. [Vancouver, BC?]: University of British Columbia , 2006.
Website
http://hdl.handle.net/2429/30974
Material Type
Thesis
Call Number
Thesis Shelf
Homeobox genes, which code for families of transcription factors, act at the top of genetic hierarchies. HOX genes specify positional identity during development, and in adult tissues, regulate differentiation and proliferation. Most ovarian carcinomas are derived from the ovarian surface epitheliu…
Website
http://hdl.handle.net/2429/30974
Author
Ota, Takayo
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2006
Subject
Faculty of Medicine
Theses
Abstract
Homeobox genes, which code for families of transcription factors, act at the top of genetic hierarchies. HOX genes specify positional identity during development, and in adult tissues, regulate differentiation and proliferation. Most ovarian carcinomas are derived from the ovarian surface epithelium (OSE). In contrast to other carcinomas, OSE differentiates further with neoplastic progression and acquires Mtillerian duct-derived epithelial properties. I tested the hypothesis that growth and differentiation in ovarian carcinogenesis are regulated by HOX genes.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Genes & development

https://cwslc.andornot.com/en/permalink/catalog119625
Cold Spring Harbor Laboratory., Genetical Society (Great Britain). Cold Spring Harbor, N.Y.: Cold Spring Harbor Laboratory Press , 1987 - Present.
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp30646&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=Genes+%26+Development
Material Type
Serial
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp30646&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=Genes+%26+Development
Alternate Title
Genes and development
Corporate Author
Cold Spring Harbor Laboratory.
Genetical Society (Great Britain)
Place of Publication
Cold Spring Harbor, N.Y.
Publisher
Cold Spring Harbor Laboratory Press
Publication Date
1987 - Present
ISSN
0890-9369
Language
English
Material Type
Serial
Frequency
Biweekly
Holdings
CFRI/Study & Learning Commons - Print: v.8:4-v.17:17 (1994-2003).
Missing: v.8:6 (1994); v.9:5 (1995); v.13:21 (1999); v.14:22 (2000); v.15:13,16,18,24 (2001); v.16:1,6 (2002).
Online: 1987 to present.
Websites
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Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp30593&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=Gene+Therapy
Place of Publication
Baltimore, MD
Publisher
Nature Publishing Group
Publication Date
1994 - Present
ISSN
0969-7128
Language
English
Material Type
Serial
Frequency
Monthly
Holdings
CFRI/Study & Learning Commons - Print: v.1:2-v.12:14,17,19-22,24 (1994-2005); + suppls.
Missing: v.8:23 (2001); v.9:5,8,20,24 (2002); v.10:22-26 (2003); v.11:11,15,19,20 (2004); v.12:1,3,5,15,16,18,23 (2005).
Online: 1997 to present.
Websites
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Goal setting and motivation in therapy: Engaging children and parents

https://cwslc.andornot.com/en/permalink/catalog120014
Philadelphia, PA: Jessica Kingsley Publishers , 2016.
Material Type
Book
Call Number
REF CC 350 POU 2015
Availability
1 copy, 1 available
Setting goals not only allows children, and their families, to engage with the overall therapeutic process, but it also provides an essential motivational element throughout the entire therapeutic process. The editors and contributors give practical advice on empathically collaborating with the chi…
Editor
Poulsen, Anne A.
Ziviani, Jenny
Cuskelly, Monica
Place of Publication
Philadelphia, PA
Publisher
Jessica Kingsley Publishers
Publication Date
2016
Physical Description
Softcover; 269 p.
Subjects
Motivational interviewing
Subject
Family Therapy
Abstract
Setting goals not only allows children, and their families, to engage with the overall therapeutic process, but it also provides an essential motivational element throughout the entire therapeutic process. The editors and contributors give practical advice on empathically collaborating with the child and his or her family, to clearly identify achievable goals that can be wholeheartedly pursued. Key information on Self-Determination Theory (SDT) is accessibly explained, which will aid professional understanding of the relationship between motivation, goal-setting, and strong therapeutic practice. The approaches in this book can be used by a wide range of professionals, including those who specialise in working with children with physical disabilities, learning disabilities, and emotional and behavioural difficulties.
ISBN
9781849054485
Material Type
Book
Call Number
REF CC 350 POU 2015

Copies

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Human gonadotropin-releasing hormone-II regulation in ovarian cancer : mechanisms and potential functional role

https://cwslc.andornot.com/en/permalink/catalog113953
Poon, Song Ling. [Vancouver, BC?]: University of British Columbia , 2010.
Website
http://hdl.handle.net/2429/30021
Material Type
Thesis
Call Number
Thesis Shelf
It is increasingly apparent that GnRH-II acts as an autocrine/paracrine regulator in non-pituitary tissues, in addition to its role in the regulation of gonadotropin synthesis, and is an important player in cancer cell biology. High levels of GnRH-II and GnRHR in malignant ovarian tumors as compare…
Website
http://hdl.handle.net/2429/30021
Author
Poon, Song Ling
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2010
Subject
Faculty of Medicine
Theses
Abstract
It is increasingly apparent that GnRH-II acts as an autocrine/paracrine regulator in non-pituitary tissues, in addition to its role in the regulation of gonadotropin synthesis, and is an important player in cancer cell biology. High levels of GnRH-II and GnRHR in malignant ovarian tumors as compared with benign ovarian tissues underlies the importance of understanding GnRH-II function in ovarian cancer. In an attempt to define the regulation of GnRH-II in these tissues, we found that a cyclic-AMP responsive element (CRE) is critical for GnRH-II promoter transcription.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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