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20 records – page 1 of 1.

Action of luteinizing hormone-releasing hormone in rat ovarian cells : hormone production and signal transduction

https://cwslc.andornot.com/en/permalink/catalog113996
Wang, Jian. [Vancouver, BC?]: University of British Columbia , 1989.
Website
http://hdl.handle.net/2429/29313
Material Type
Thesis
Call Number
Thesis Shelf
The present study was conducted to investigate the hypothesis that membrane phosphoinositide breakdown may participate in the actions of luteinizing hormone-releasing hormone (LHRH) on hormone production in the rat ovary. In granulosa cells prelabeled with [³H]-arachidonic acid or [³H]-inositol, tr…
Website
http://hdl.handle.net/2429/29313
Author
Wang, Jian
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1989
Subject
Faculty of Medicine
Theses
Abstract
The present study was conducted to investigate the hypothesis that membrane phosphoinositide breakdown may participate in the actions of luteinizing hormone-releasing hormone (LHRH) on hormone production in the rat ovary. In granulosa cells prelabeled with [³H]-arachidonic acid or [³H]-inositol, treatment with LHRH increased the accumulation of radiolabeled inositol lipids, diacylglycerol and free arachidonic acid, but luteinizing hormone (LH) or cholera toxin did not exert the same effect. Activation of protein kinase C by the phorbol ester, 12-0-tetradecanoyl phorbol-13-acetate (TPA) had a stimulatory action on membrane phosphoinositide breakdown.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Arteriosclerosis, thrombosis and vascular biology

https://cwslc.andornot.com/en/permalink/catalog114440

Biology of Reproduction

https://cwslc.andornot.com/en/permalink/catalog114443
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp16131&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=cell
Corporate Author
Massachusetts Institute of Technology
Place of Publication
Cambridge, Ma.
Publisher
Elsevier
Publication Date
1974 - present.
ISSN
0092-8674
Language
English
Material Type
Serial
Frequency
Biweekly
Holdings
CFRI/Study & Learning Commons - Print: v.76:1-v.98:4 (1994-1998); v.104:1-v.156:3+suppls. (2001-2014).
Missing: v.78:7, v.79:2 (1994); v.80:7, v.81:6, v.82:4,7 (1995); v.84:7, v.85:1, v.86:1,7 (1996); v.88:7, v.90:3,7 (1997); v.92:1,4,7, v.93:3-5, v.94, v.95:1-3,5,6 (1998); v.96:2,7, v.97:1-6 (1999); v.104:6 (2001); v.111:4 (2002); v.117:1 (2004); v.141:4 (2010).
Online: 1974 to present.
Websites
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Characterization of the human gonadotropin-releasing hormone receptor gene at the molecular level

https://cwslc.andornot.com/en/permalink/catalog113982
Fan, Nancy C. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7255
Material Type
Thesis
Call Number
Thesis Shelf
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling sti…
Website
http://hdl.handle.net/2429/7255
Author
Fan, Nancy C.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling stimulates the synthesis and release of both luteinizing hormone and follicle stimulating hormone from the anterior pituitary. In addition, GnRH - GnRH receptor binding acts locally to regulate human chorionic gonadotropin secretion in the placenta and steroidogenesis in the ovary. The objective of this thesis was to isolate and characterize the gene for the GnRH receptor in human.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Clinical Genetics: An International Journal of Genetics, Molecular and Personalized Medicine

https://cwslc.andornot.com/en/permalink/catalog114754
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp18084&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=clinical+genetics
Place of Publication
Malden, Ma.
Publisher
John Wiley & Sons, Inc.
Publication Date
1970 - Present.
ISSN
0009-9163
Language
English
Material Type
Serial
Frequency
Monthly
Holdings
CFRI/Study & Learning Commons - Print: v.45:6-v.57:4+special issue (1994-2000); v.61:1 (2002); v.69:3-v.76:3 (2006-2009).
Missing: v.51:3, v.52:4 (1997); v.53:2 (1998); v.55:4, v.56:1,3 (1999); v.57:1-3, v.58:1-6 (2000); v.59:1-6, v.60:1-6 (2001); v.61:2-6, v.62:1-6 (2002); 2003-2005; v.69:1-2 (2006); v.73:3-5 (2008); v.75:1,3,4, v.76:2,4-6 (2009).
Online: 1970 to present.
Websites
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Current Opinion in Cell Biology

https://cwslc.andornot.com/en/permalink/catalog114768
Website
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=current+opinion+in+cell+biology
Place of Publication
[United Kingdom]
Publisher
Elsevier B.V.
Publication Date
1989 - Present
ISSN
0955-0674
Language
English
Material Type
Serial
Frequency
Bimonthly
Holdings
CFRI/Study & Learning Commons - Print: v.10:1-v.18:1 (1998-2006).
Missing: v.10:2 (1998); v.11:3,6 (1999); v.12:6 (2000); v.13:1-2 (2001); v.14:1,3 (2002); v.v.15:5-6 (2003); v.16:3 (2004); v.17:4 (2005); v.18:2-6 (2006).
Online: 1989 to present.
Websites
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Effects and mechanisms of growth differentiation factor 9 on activin A-regulated inhibin B and progesterone production in human granulosa cells

https://cwslc.andornot.com/en/permalink/catalog113951
Shi, Fengtao. [Vancouver, BC?]: University of British Columbia , 2010.
Website
http://hdl.handle.net/2429/28961
Material Type
Thesis
Call Number
Thesis Shelf
Activin A (homodimer of inhibin βA-subunit) is known to increase inhibin βB-subunit and inhibin B (heterodimer of inhibin α- and βB-subunit) levels and decrease progesterone accumulation in human granulosa cells. Growth differentiation factor 9 (GDF9) is a potent paracrine regul…
Website
http://hdl.handle.net/2429/28961
Author
Shi, Fengtao
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2010
Subject
Faculty of Medicine
Theses
Abstract
Activin A (homodimer of inhibin βA-subunit) is known to increase inhibin βB-subunit and inhibin B (heterodimer of inhibin α- and βB-subunit) levels and decrease progesterone accumulation in human granulosa cells. Growth differentiation factor 9 (GDF9) is a potent paracrine regulator of ovarian function, but its overall effects, particularly relating to activin A actions, are unknown. We examined the potential crosstalk between activin A and GDF9 in primary cultures of human granulosa-lutein (hGL) cells. Pretreatment of hGL cells with GDF9 for 24 h resulted in an increased expression of activin receptors and Smad2/3, and decreased inhibitory Smad7 activity. These effects were attenuated by BMP type II receptor ectodomain (BMPR2 ECD), a GDF9 antagonist.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Gonadotropins and leptin : the role and molecular mechanism in normal and neoplastic ovarian epithelium cells

https://cwslc.andornot.com/en/permalink/catalog113965
Choi, Jung-Hye. [Vancouver, BC?]: University of British Columbia , 2006.
Website
http://hdl.handle.net/2429/18509
Material Type
Thesis
Call Number
Thesis Shelf
Ovarian cancer is the sixth most common cancer and the fifth leading cause of cancer-related death among women in developed countries. There is increasing evidence suggesting that the hormonal environment of the normal ovarian surface epithelium (OSE) and ovarian epithelial cancer (OEC) cells is as…
Website
http://hdl.handle.net/2429/18509
Author
Choi, Jung-Hye
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2006
Subject
Faculty of Medicine
Theses
Abstract
Ovarian cancer is the sixth most common cancer and the fifth leading cause of cancer-related death among women in developed countries. There is increasing evidence suggesting that the hormonal environment of the normal ovarian surface epithelium (OSE) and ovarian epithelial cancer (OEC) cells is associated with the development and progression of ovarian cancer. Exposure to excess gonadotropins and leptin, related to menopause or infertility therapy and obesity, respectively, has been implicated as a risk factor for ovarian cancer.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Human molecular genetics

https://cwslc.andornot.com/en/permalink/catalog119692
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp33596&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=human+molecular+genetics
Place of Publication
Oxford, England
Publisher
Oxford University Press
Publication Date
1992 - Present
ISSN
0964-6906
Language
English
Material Type
Serial
Frequency
Bimonthly
Holdings
CFRI/Study & Learning Commons - Print: v.3:1-v.8:13 (1994-1999); v.9:15-16 (2000); v.10:1-16,19,20,22-25 (2001); v.11:17,20 (2002); v.12:13 (2003).
Missing: v.4:8 (1995); v.5:8 (1996); v.6:8,10 (1997).
Online: 1992 to present.
Websites
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Localization and regulation of mRNA transcripts encoding activin receptors in human placental trophoblast cells

https://cwslc.andornot.com/en/permalink/catalog113978
Chen, Victor. [Vancouver, BC?]: University of British Columbia , 1997.
Website
http://hdl.handle.net/2429/6315
Material Type
Thesis
Call Number
Thesis Shelf
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type…
Website
http://hdl.handle.net/2429/6315
Author
Chen, Victor
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1997
Subject
Faculty of Medicine
Theses
Abstract
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type II (II and ILB) receptors. The role of activin in the human placenta is not clearly understood. In this study, the detection of inlubin/activin subunit and ActRI mRNA were examined in first trimester cytotrophoblasts, term cytotrophoblasts, extravillous trophoblast (EVT) cells, immortalized extravillous trophoblast (LEVT) cells, JEG-3 cells, decidual tissue, and decidual cells.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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The molecular biology of calbindin-D9k

https://cwslc.andornot.com/en/permalink/catalog113987
Jeung, Eui-Bae. [Vancouver, BC?]: University of British Columbia , 1993.
Website
http://hdl.handle.net/2429/1766
Material Type
Thesis
Call Number
Thesis Shelf
Calbindin-D9k is a cytosolic calcium binding protein expressed in the mammalian intestine, placenta, and uterus. The protein is probably involved in calcium transport across the intestinal and placental epithelia. The objective of this thesis was to study the structure of the human and porcine calb…
Website
http://hdl.handle.net/2429/1766
Author
Jeung, Eui-Bae
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1993
Subject
Faculty of Medicine
Theses
Abstract
Calbindin-D9k is a cytosolic calcium binding protein expressed in the mammalian intestine, placenta, and uterus. The protein is probably involved in calcium transport across the intestinal and placental epithelia. The objective of this thesis was to study the structure of the human and porcine calbindin-D9k at the cDNA and genomic level. The cDNAs for the bovine, murine, and ratcalbindin-D9k as well as the gene for rat calbindin-D9k had been cloned previously.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Molecular endocrinology

https://cwslc.andornot.com/en/permalink/catalog119757
Website
PHSA Users:
http://search.ebscohost.com/login.aspx?direct=true&db=edspub&AN=edp49672&site=pfi-live
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_M&C=Molecular+Endocrinology
Alternate Title
Mol. Endocrinol.
Place of Publication
Baltimore, md.
Publisher
Endocrine Society
Publication Date
1987 - Present.
ISSN
0888-8809
Language
English
Material Type
Serial
Frequency
Monthly
Holdings
CFRI/Study & Learning Commons - Print: v.1:1-v.25:7 (1987-2011).
Missing: v.17:1-3 (2003); v.19:10 (2005); v.20:3-12 (2006); v.23:3,4,10 (2009); v.25:2,8-12 (2001).
Online: 1997 to present.
Websites
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20 records – page 1 of 1.