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Before We Are Born:: Essentials of Embryology and Birth Defects

https://cwslc.andornot.com/en/permalink/catalog125205
Wynbrandt, James., Ludman, Mark D. New York, NY: Elsevier Canada , 2019. 10th.
Material Type
Book
Call Number
REF GI 200 MOO 2019
Availability
1 copy, 1 available
Covering the essentials of normal and abnormal human development for students in a variety of health science disciplines,Before We Are Born: Essentials of Embryology and Birth Defects, 10th Edition,reflects new research findings and current clinical practice through concise text and abundant illust…
Author
Wynbrandt, James.
Ludman, Mark D.
Edition
10th
Place of Publication
New York, NY
Publisher
Elsevier Canada
Publication Date
2019
Physical Description
Hardcover, 350 pp.
Subject
Genetics/Genetic Disorders-Encyclopedias
Genetic Disorders
Birth Defects. Congenital Abnormalities
Children's Health-Encyclopedias
UBC MD Undergrad
Abstract
Covering the essentials of normal and abnormal human development for students in a variety of health science disciplines,Before We Are Born: Essentials of Embryology and Birth Defects, 10th Edition,reflects new research findings and current clinical practice through concise text and abundant illustrations . This edition has been fully updated by the world's foremost embryologists and is based on the popular text,The Developing Human, written by the same author team. It provides an easily accessible understanding of all of the latest advances in embryology, includingnormal and abnormal embryogenesis, causes of birth defects, and the role of genes in human development.
ISBN
978-0323608497
Language
English
Material Type
Book
Call Number
REF GI 200 MOO 2019

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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Being buddha at work: 108 ancient truths on change, stress, money & success

https://cwslc.andornot.com/en/permalink/catalog112929
Metcalf, Franz, Gallagher, BJ. San Francisco, CA: Berrett-Koehler , 2012.
Material Type
Book
Call Number
REF AA 75 MET 2012
Availability
2 copies, 2 available
"Being Buddah at Work" explores and answers 101 dilemmas that we encounter at work, with topics ranging from time management, goal-setting, conflict to job dissatisfaction, unemployment, and even workplace trysts. The authors emphasize practical learning and coping, not esoteric insights or metaphy…
Author
Metcalf, Franz
Gallagher, BJ
Place of Publication
San Francisco, CA
Publisher
Berrett-Koehler
Publication Date
2012
Physical Description
Paperback: 176 p.
Subject
Leadership/Coaching
Abstract
"Being Buddah at Work" explores and answers 101 dilemmas that we encounter at work, with topics ranging from time management, goal-setting, conflict to job dissatisfaction, unemployment, and even workplace trysts. The authors emphasize practical learning and coping, not esoteric insights or metaphysics, applying concrete solutions from Buddhist teachings to real problems.
ISBN
9781609942922
Language
English
Material Type
Book
Call Number
REF AA 75 MET 2012

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A Biological role for GnRH I and GnRH II at the maternal-fetal interface

https://cwslc.andornot.com/en/permalink/catalog113971
Zhou, Junshan. [Vancouver, BC?]: University of British Columbia , 2003.
Website
http://hdl.handle.net/2429/14957
Material Type
Thesis
Call Number
Thesis Shelf
Remodeling of the endometrial extracellular matrix, which occurs during the early stages of pregnancy in the human, is mediated by the temporal expression of urokinase-type plasminogen activator (uPA) and matrix metalloproteinases (MMP) in both the maternal and fetal compartments and counterbalance…
Website
http://hdl.handle.net/2429/14957
Author
Zhou, Junshan
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2003
Subject
Faculty of Medicine
Theses
Abstract
Remodeling of the endometrial extracellular matrix, which occurs during the early stages of pregnancy in the human, is mediated by the temporal expression of urokinase-type plasminogen activator (uPA) and matrix metalloproteinases (MMP) in both the maternal and fetal compartments and counterbalanced by their respective endogenous inhibitors, plasminogen activator inhibitor (PAI-1) and tissue inhibitors of metalloproteinases (TIMPs) in both an autocrine and paracrine manner. To date, the factors capable of regulating the expression of uPA and MMP proteolytic systems at the maternal-fetal interface remain poorly characterized.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Blueprints: Family medicine

https://cwslc.andornot.com/en/permalink/catalog112766
Lipsky, Martin S., King, Mitchell S. Baltimore, MD: Lippincott Williams & Wilkins, a Wolters Kluwer business , 2011. 3rd Ed.
Material Type
Book
Call Number
REF FA 310 LIP 2010
Availability
1 copy, 1 available
This resource provides students with a complete review of key concepts and topics and serves as a rapid reference during day-to-day activities in patient care—perfect for clerkship rotations and the USMLE.
Author
Lipsky, Martin S.
King, Mitchell S.
Edition
3rd Ed.
Place of Publication
Baltimore, MD
Publisher
Lippincott Williams & Wilkins, a Wolters Kluwer business
Publication Date
2011
Physical Description
Paperback: 329 pages
Subject
Family Medicine-Directories. Resource Guides
Medical Directories. Resource Guides
UBC MD Undergrad
Abstract
This resource provides students with a complete review of key concepts and topics and serves as a rapid reference during day-to-day activities in patient care—perfect for clerkship rotations and the USMLE.
ISBN
978-1608310876
Language
English
Material Type
Book
Call Number
REF FA 310 LIP 2010

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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Blueprints: Family medicine

https://cwslc.andornot.com/en/permalink/catalog121447
Lipsky, Martin S., King, Mitchell S. Baltimore, MD: Lippincott Williams & Wilkins, a Wolters Kluwer business , 2019. 4th Ed.
Material Type
Book
Call Number
REF FA 310 LIP 2019
Availability
2 copies, 2 available
This resource provides students with a complete review of key concepts and topics and serves as a rapid reference during day-to-day activities in patient care—perfect for clerkship rotations and the USMLE.
Author
Lipsky, Martin S.
King, Mitchell S.
Edition
4th Ed.
Place of Publication
Baltimore, MD
Publisher
Lippincott Williams & Wilkins, a Wolters Kluwer business
Publication Date
2019
Physical Description
Paperback: 497 pages
Subject
Family Medicine-Directories. Resource Guides
Medical Directories. Resource Guides
UBC MD Undergrad
Abstract
This resource provides students with a complete review of key concepts and topics and serves as a rapid reference during day-to-day activities in patient care—perfect for clerkship rotations and the USMLE.
ISBN
978-1496377883
Language
English
Material Type
Book
Call Number
REF FA 310 LIP 2019

Copies

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Blueprints: Medicine

https://cwslc.andornot.com/en/permalink/catalog112765
Young, Vincent B., Chick, Davoren A., Kormos, William A., Goroll, Allan H. Baltimore, MD: Lippincott Williams & Wilkins, a Wolters Kluwer business , 2016. 6th Ed.
Material Type
Book
Call Number
REF FA 22 YOU 2016
Availability
2 copies, 2 available
This book provides a concise review of what students need to know in their rotations or the Boards. Each chapter is brief and includes pedagogical features such as bold key words, tables, figures, and key points boxes. This edition has been reorganized to follow the Clerkship Directors in Internal …
Author
Young, Vincent B.
Chick, Davoren A.
Kormos, William A.
Goroll, Allan H.
Edition
6th Ed.
Place of Publication
Baltimore, MD
Publisher
Lippincott Williams & Wilkins, a Wolters Kluwer business
Publication Date
2016
Physical Description
Paperback: 403 pages
Subject
Medical Directories. Resource Guides
General Medicine-Directories. Resource Guides
UBC MD Undergrad
Abstract
This book provides a concise review of what students need to know in their rotations or the Boards. Each chapter is brief and includes pedagogical features such as bold key words, tables, figures, and key points boxes. This edition has been reorganized to follow the Clerkship Directors in Internal Medicine guidelines, and includes a new section on neurology, case studies, and additional tables and figures. A question-and-answer section at the end of the book includes 100 board-format questions with complete rationales for each answer choice.
ISBN
9781469864150
Language
English
Material Type
Book
Call Number
REF FA 22 YOU 2016

Copies

Copy 1 BC Children's and Women's Study and Learning Commons MISSING Available
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Book of awesome: Snow days, bakery air, finding money in your pocket, and other simple, brilliant things

https://cwslc.andornot.com/en/permalink/catalog112885
Pasricha, Neil. New York, NY: Berkley , 2010.
Website
1000awesomethings.com
Material Type
Book
Call Number
REF AA 75 PAS 2010
Availability
1 copy, 1 available
The Book of Awesome is a high five for humanity and a big celebration of life's little moments and the underappreciated, simple things that make us happy.
Website
1000awesomethings.com
Author
Pasricha, Neil
Place of Publication
New York, NY
Publisher
Berkley
Publication Date
2010
Physical Description
Paperback: 393 p.
Subject
Leadership/Coaching
Abstract
The Book of Awesome is a high five for humanity and a big celebration of life's little moments and the underappreciated, simple things that make us happy.
ISBN
9780425238905
Language
English
Material Type
Book
Call Number
REF AA 75 PAS 2010

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF AA 75 PAS 2010 MISSING Available
Websites
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Braunwald's heart disease: A textbook of cardiovascular medicine: Volume 1

https://cwslc.andornot.com/en/permalink/catalog112636
Zipes, Douglas P., Libby, Peter, Bonow, Robert O., Braunwald, Eugene. Philadelphia, PA: Elsevier Saunders , 2005. 7th ed.
Material Type
Book
Call Number
REF FD 200 ZIP 2005 v.1
Availability
1 copy, 1 available
Volume 1 of this 7th edition contains 36 new chapters and full-color figures and photographs. Compared with the rather limited color-plate photographs in the sixth edition, the color photographs, figures, and tables in each chapter significantly enhance the new text. Informative chapters on the fou…
Author
Zipes, Douglas P.
Libby, Peter
Bonow, Robert O.
Braunwald, Eugene
Edition
7th ed
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Publication Date
2005
Physical Description
Hardcover: 1102 p.
Subject
Cardiovascular System-Anatomy/Physiology
Heart/Heart Diseases. Cardiology
UBC MD Undergrad
Abstract
Volume 1 of this 7th edition contains 36 new chapters and full-color figures and photographs. Compared with the rather limited color-plate photographs in the sixth edition, the color photographs, figures, and tables in each chapter significantly enhance the new text. Informative chapters on the foundations of cardiovascular medicine remain, including detailed discussions of history taking, physical examination, and electrocardiography, topics often overshadowed in an era of rapidly progressive medical technology.
ISBN
9789997637383
Language
English
Material Type
Book
Call Number
REF FD 200 ZIP 2005 v.1

Copies

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Braunwald's heart disease: A textbook of cardiovascular medicine: Volume 2

https://cwslc.andornot.com/en/permalink/catalog112637
Zipes, Douglas P., Libby, Peter, Bonow, Robert O., Braunwald, Eugene. Philadelphia, PA: Elsevier Saunders , 2005. 7th ed.
Material Type
Book
Call Number
REF FD 200 ZIP 2005 v.2
Availability
1 copy, 1 available
Volume 2 of this 7th edition contains 36 new chapters and full-color figures and photographs. Compared with the rather limited color-plate photographs in the sixth edition, the color photographs, figures, and tables in each chapter significantly enhance the new text. Informative chapters on the fou…
Author
Zipes, Douglas P.
Libby, Peter
Bonow, Robert O.
Braunwald, Eugene
Edition
7th ed
Place of Publication
Philadelphia, PA
Publisher
Elsevier Saunders
Publication Date
2005
Physical Description
Hardcover: 2183 p.
Subject
Cardiovascular System/Cardiovascular System Diseases
Heart/Heart Diseases. Cardiology
UBC MD Undergrad
Abstract
Volume 2 of this 7th edition contains 36 new chapters and full-color figures and photographs. Compared with the rather limited color-plate photographs in the sixth edition, the color photographs, figures, and tables in each chapter significantly enhance the new text. Informative chapters on the foundations of cardiovascular medicine remain, including detailed discussions of history taking, physical examination, and electrocardiography, topics often overshadowed in an era of rapidly progressive medical technology.
ISBN
9789997637390
Language
English
Material Type
Book
Call Number
REF FD 200 ZIP 2005 v.2

Copies

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Building peer accountability: Toolkit for improving communication and collaboration

https://cwslc.andornot.com/en/permalink/catalog113762
Nursing Executive Centre. Washington, DC: The Advisory Board Company , 2011.
Material Type
Book
Call Number
REF JC 500 NUR 2011
Availability
4 copies, 4 available
Toolkit contains seven exercises to teach frontline nurses to deliver timely and effective peer feedback.
Corporate Author
Nursing Executive Centre
Place of Publication
Washington, DC
Publisher
The Advisory Board Company
Publication Date
2011
Physical Description
Spiralbound softcover:62 pages
Subject
Nursing. Registered Nurse. RN
Leadership/Coaching
Abstract
Toolkit contains seven exercises to teach frontline nurses to deliver timely and effective peer feedback.
Language
English
Material Type
Book
Call Number
REF JC 500 NUR 2011

Copies

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Canadian Essentials of Pediatric Nursing

https://cwslc.andornot.com/en/permalink/catalog125211
Ateah, Christine A, Scott, Shannon D., Kyle, Terri. New York, NY: Wolters Kluwer , 2019. 1st.
Material Type
Book
Call Number
CA 210 ATE 2019
Availability
1 copy, 1 available
In pediatric nursing, the ability to apply previously learned concepts to new situations is critical. In today's educational climate, with reduced class time being devoted to specialty areas, it is particularly important for nursing educators to focus on key concepts, rather than attempting to cove…
Author
Ateah, Christine A
Scott, Shannon D.
Kyle, Terri
Edition
1st
Place of Publication
New York, NY
Publisher
Wolters Kluwer
Publication Date
2019
Physical Description
1192 pp Hardcover
Subjects
Pediatrics
Nursing
Subject
Nursing Education
Infants
Children
Abstract
In pediatric nursing, the ability to apply previously learned concepts to new situations is critical. In today's educational climate, with reduced class time being devoted to specialty areas, it is particularly important for nursing educators to focus on key concepts, rather than attempting to cover everything within a specific topic.
The intent ofCanadianEssentials of Pediatric Nursingis to provide the nurse with the basis needed for sound nursing care of children. The main objective is to aid the students in building a strong knowledge base that reflects the Canadian context as well as to assist with the development of critical thinking skills. The book covers a broad scope of topics, placing emphasis on common issues and pediatric-specific content. The text presents the important differences when caring for children as compared to caring for adults. Rather than repeating medical-surgical content, the text builds upon that knowledge base. A nursing process approach provides relevant information in a concise and non-redundant manner. In Unit IV, specific nursing process content is discussed as appropriate for given disorders.
Each chapter ofCanadianEssentials of Pediatric Nursingfocuses on a different aspect of pediatric nursing care. The book is divided into four units, beginning with general concepts related to pediatric nursing and followed by normal growth and development and specifics related to caring for children. The fourth unit focuses on nursing management of alterations in children's health. The content of this text reflects Canadian trends and statistics (when available).
ISBN
978-1609137076
Language
English
Material Type
Book
Call Number
CA 210 ATE 2019

Copies

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Canadian journal of rural medicine: The official journal of the Society of Rural Physicians of Canada

https://cwslc.andornot.com/en/permalink/catalog114596
Website
PHSA Users:
http://web.a.ebscohost.com/pfi/detail/detail?vid=15&sid=80dd29ce-f1c9-480f-93d5-346abac169f7%40sessionmgr4009&hid=4106&bdata=JnNpdGU9cGZpLWxpdmU%3d#AN=edp15358&db=edspub
UBC Users:
http://gw2jh3xr2c.search.serialssolutions.com/?SS_searchTypeJournal=yes&V=1.0&L=GW2JH3XR2C&S=AC_T_B&C=Canadian+journal+of+rural+medicine
Alternate Title
Canadian journal of rural medicine : the official journal of the Society of Rural Physicians of Canada = Journal canadien de la médecine rurale : le journal officiel de la Société de médecine rurale du Canada.
Corporate Author
Society of Rural Physicians of Canada
Place of Publication
[Ottawa, ON]
Publisher
Canadian Medical Association
Publication Date
1996 - Present
Notes
Articles in English; some are also in French.
ISSN
1203-7796
Language
English, French
Material Type
Serial
Frequency
Quarterly
Holdings
CFRI/Study & Learning Commons - Print:v.10:1-v.15:4 (2005-2010); v.16:3 (2011); v.17:1-2 (2012).
Missing: v.8:2-4 (2003); v.9:1-4 (2004); v.11:4 (2006); v.12:4 (2007); v.13:2 (2008).
Online: 1996 to present.
Websites
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Canadian Perspectives on Advanced Practice Nursing

https://cwslc.andornot.com/en/permalink/catalog125189
Toronto, Canada: Canadian Scholars , 2020. 2nd.
Material Type
Book
Call Number
REF JC 500 STA 2020
Availability
1 copy, 1 available
This expanded second edition of Canadian Perspectives on Advanced Practice Nursing uses a case-study approach to understanding advanced practice nursing roles and competencies and their impact across all levels of the health care system. Focusing on the roles of clinical nurse specialists and nurse…
Editor
Staples, Eric
Pilon, Roger
Hannon, Ruth A.
Edition
2nd
Place of Publication
Toronto, Canada
Publisher
Canadian Scholars
Publication Date
2020
Physical Description
584 pp
Subjects
Nursing. Registered Nurse. RN
Leadership/Coaching
Advanced Practice Nursing
Abstract
This expanded second edition of Canadian Perspectives on Advanced Practice Nursing uses a case-study approach to understanding advanced practice nursing roles and competencies and their impact across all levels of the health care system. Focusing on the roles of clinical nurse specialists and nurse practitioners, this volume explores the continued integration of advanced practice nursing in relation to social, political, educational, regulatory, legislative, and economic environments that have shaped them. The contributors articulate the historical development and evolution of advanced practice nursing in Canada, from rural and remote outpost beginnings to the present, and propose a vision for the future within the Canadian health care system.
Highly accessible, comprehensive, and rich in pedagogy, this well-updated new edition is an indispensable resource for students in advanced practice nursing programs across Canada, as well as practicing clinical nurse specialists, nurse practitioners, policy- and decisionmakers, professional nursing organizations, and leaders in health care.
ISBN
978-1773382173
Language
English
Material Type
Book
Call Number
REF JC 500 STA 2020

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Cardiovascular, metabolic, endocrine and behavioral aspects of development in postnatal lambs in relation to age, sex, lamb number and acute fluoxetine administration

https://cwslc.andornot.com/en/permalink/catalog113943
Nguyen, Tuan-Anh Thi. [Vancouver, BC?]: University of British Columbia , 2013.
Website
http://hdl.handle.net/2429/44653
Material Type
Thesis
Call Number
Thesis Shelf
Human newborns exposed in utero to maternally administered SSRIs such as fluoxetine (FX) have an increased risk of adverse pregnancy outcomes including poor neonatal adaptation. This comprises respiratory difficulty, jitteriness, cyanosis when feeding and persists for several days after birth. Seve…
Website
http://hdl.handle.net/2429/44653
Author
Nguyen, Tuan-Anh Thi
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2013
Subject
Faculty of Medicine
Theses
Abstract
Human newborns exposed in utero to maternally administered SSRIs such as fluoxetine (FX) have an increased risk of adverse pregnancy outcomes including poor neonatal adaptation. This comprises respiratory difficulty, jitteriness, cyanosis when feeding and persists for several days after birth. Several potential mechanisms underlying these symptoms have been proposed: 1) acute toxicity to the drugs (i.e. serotonin syndrome), 2) withdrawal syndrome due to the sudden discontinuation of maternal-fetal placental drug transfer at birth or 3) an SSRIs-elicited alteration in fetal brain development. However, the actual mechanism has not been elucidated.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Case files: Internal medicine

https://cwslc.andornot.com/en/permalink/catalog114803
Toy, Eugene, Patlan, John, Warner, Mark T. New York, NY: McGraw-Hill Education , 2017. 5th ed.
Material Type
Book
Call Number
REF AB 60 TOY 2017
Availability
2 copies, 2 available
Experience with clinical cases is key to mastering the art and science of medicine. This book provides 60 true-to-life cases that illustrate essential concepts in Internal Medicine. Each case includes a discussion correlated to key concepts, definitions of key terms, clinical pearls, and board-styl…
Author
Toy, Eugene
Patlan, John
Warner, Mark T.
Edition
5th ed.
Place of Publication
New York, NY
Publisher
McGraw-Hill Education
Publication Date
2017
Physical Description
Paperback, 588 p.
Subject
Internal Medicine
Abstract
Experience with clinical cases is key to mastering the art and science of medicine. This book provides 60 true-to-life cases that illustrate essential concepts in Internal Medicine. Each case includes a discussion correlated to key concepts, definitions of key terms, clinical pearls, and board-style review questions to reinforce your learning.
ISBN
9780071843355
Language
English
Material Type
Book
Call Number
REF AB 60 TOY 2017

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Change your questions change your life: 10 powerful tools for life and work

https://cwslc.andornot.com/en/permalink/catalog123809
Adams, Marilee. San Francisco: CA: Berrett-Koehler Publishers, Inc. , 2015. 3rd Edition.
Material Type
Book
Call Number
REF AA 75 ADA 2015
Availability
1 copy, 0 available
Questions are at the core of how we listen, behave, think, and relate--as individuals and organizations. Virtually everything we think and do is generated by questions. Questions push us into new territories. The future begins with our thinking, represented by the questions we ask ourselves. This b…
Author
Adams, Marilee
Edition
3rd Edition
Place of Publication
San Francisco: CA
Publisher
Berrett-Koehler Publishers, Inc.
Publication Date
2015
Physical Description
Paperback: 233 pages
Subject
Leadership/Coaching
Abstract
Questions are at the core of how we listen, behave, think, and relate--as individuals and organizations. Virtually everything we think and do is generated by questions. Questions push us into new territories. The future begins with our thinking, represented by the questions we ask ourselves. This book shows readers how to consistently choose the questions that can lead them to success, both personally and professionally. This technique, called "QuestionsThinking, stimulates innovation, accelerate productivity, and create more rewarding relationships.
Notes
RESTRICTED TO PHSA LEADERSHIP COACHING PARTICIPANTS ONLY.
ISBN
9781-62656 6330
Language
English
Material Type
Book
Call Number
REF AA 75 ADA 2015

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Copy 1 BC Children's and Women's Study and Learning Commons REF On Loan, due Wednesday, June 12, 2024
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Change your questions change your life: 10 powerful tools for life and work

https://cwslc.andornot.com/en/permalink/catalog111324
Adams, Marilee. San Francisco: CA: Berrett-Koehler Publishers, Inc. , 2009. 2nd Edition.
Material Type
Book
Call Number
REF AA 75 ADA 2009
Availability
48 copies, 39 available
Questions are at the core of how we listen, behave, think, and relate--as individuals and organizations. Virtually everything we think and do is generated by questions. Questions push us into new territories. The future begins with our thinking, represented by the questions we ask ourselves. This b…
Author
Adams, Marilee
Edition
2nd Edition
Place of Publication
San Francisco: CA
Publisher
Berrett-Koehler Publishers, Inc.
Publication Date
2009
Physical Description
Paperback: 196 pages
Subject
Leadership/Coaching
Abstract
Questions are at the core of how we listen, behave, think, and relate--as individuals and organizations. Virtually everything we think and do is generated by questions. Questions push us into new territories. The future begins with our thinking, represented by the questions we ask ourselves. This book shows readers how to consistently choose the questions that can lead them to success, both personally and professionally. This technique, called "QuestionsThinking, stimulates innovation, accelerate productivity, and create more rewarding relationships.
Notes
RESTRICTED TO PHSA LEADERSHIP COACHING PARTICIPANTS ONLY.
ISBN
9781576756003
Language
English
Material Type
Book
Call Number
REF AA 75 ADA 2009

Copies

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The characterization of ADAMTS-12 in the regulation of human trophoblast invasion in vitro

https://cwslc.andornot.com/en/permalink/catalog113949
Zou, Junxuan. [Vancouver, BC?]: University of British Columbia , 2010.
Website
http://hdl.handle.net/2429/29783
Material Type
Thesis
Call Number
Thesis Shelf
The distintegrin-like and metalloproteinase with thrombospondin repeats (ADAMTS) are members of a gene family of secreted, multidomain and multifunctional proteinases that are able to proteolytically degrade a diverse array of cellular, extracellular and extracellular matrix (ECM) substrates. We ex…
Website
http://hdl.handle.net/2429/29783
Author
Zou, Junxuan
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2010
Subject
Faculty of Medicine
Theses
Abstract
The distintegrin-like and metalloproteinase with thrombospondin repeats (ADAMTS) are members of a gene family of secreted, multidomain and multifunctional proteinases that are able to proteolytically degrade a diverse array of cellular, extracellular and extracellular matrix (ECM) substrates. We examined the presence of ADAMTS in first trimester human placenta and only ADAMTS-12 was present in cultures of invasive extravillous cytotrophoblast (EVT) at significantly higher levels than in poorly invasive JEG-3 chorocarcinoma cells. Immunohistochemistry staining of chorionic villi derived from first trimester human placenta demonstrated that ADAMTS-12 was intensively immunolocalized in the cytotrophoblast layer but weakly immunolocalized in the poorly-invasive syncytial trophoblast layer.
Language
English
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Characterization of the human gonadotropin-releasing hormone receptor gene at the molecular level

https://cwslc.andornot.com/en/permalink/catalog113982
Fan, Nancy C. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7255
Material Type
Thesis
Call Number
Thesis Shelf
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling sti…
Website
http://hdl.handle.net/2429/7255
Author
Fan, Nancy C.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling stimulates the synthesis and release of both luteinizing hormone and follicle stimulating hormone from the anterior pituitary. In addition, GnRH - GnRH receptor binding acts locally to regulate human chorionic gonadotropin secretion in the placenta and steroidogenesis in the ovary. The objective of this thesis was to isolate and characterize the gene for the GnRH receptor in human.
Language
English
Material Type
Thesis
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Characterizations of a tumor-associated antigen COX-1

https://cwslc.andornot.com/en/permalink/catalog113988
Sheu, Fong-Shyong. [Vancouver, BC?]: University of British Columbia , 1991.
Website
http://hdl.handle.net/2429/30332
Material Type
Thesis
Call Number
Thesis Shelf
By using modified hybridoma technology, monoclonal antibodies against an ovarian tumor cell line, OC-3-VGH, were generated in Dr. Lee's laboratory. Among these antibodies, RP 215 was shown to react specifically with a tumor-associated antigen, COX-1. On SDS gel, COX-1 has a molecular weight of 60 K…
Website
http://hdl.handle.net/2429/30332
Author
Sheu, Fong-Shyong
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1991
Subject
Faculty of Medicine
Theses
Abstract
By using modified hybridoma technology, monoclonal antibodies against an ovarian tumor cell line, OC-3-VGH, were generated in Dr. Lee's laboratory. Among these antibodies, RP 215 was shown to react specifically with a tumor-associated antigen, COX-1. On SDS gel, COX-1 has a molecular weight of 60 KD and exists as an aggregate in the natural- state. A highly purified COX-1 was obtained mainly by immunoaffirtity chromatography, with RP 215 as the affinity ligand, from the shed medium of cultured tumor cells.
Language
English
Material Type
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