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20 records – page 1 of 1.

Chromosome segregation and meiotic defects in carriers of chromosomal abnormalities

https://cwslc.andornot.com/en/permalink/catalog113956
Kirkpatrick, Gordon. [Vancouver, BC?]: University of British Columbia , 2009.
Website
http://hdl.handle.net/2429/9705
Material Type
Thesis
Call Number
Thesis Shelf
Male carriers of chromosomal abnormalities (CA) are more frequent in the infertile population. These men have higher levels of sperm aneuploidy due to the aberrant segregation of the chromosomes involved in the abnormality. The presence of a CA may also influence the segregation of other chromosome…
Website
http://hdl.handle.net/2429/9705
Author
Kirkpatrick, Gordon
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2009
Subject
Faculty of Medicine
Theses
Abstract
Male carriers of chromosomal abnormalities (CA) are more frequent in the infertile population. These men have higher levels of sperm aneuploidy due to the aberrant segregation of the chromosomes involved in the abnormality. The presence of a CA may also influence the segregation of other chromosomes, in a process known as in interchromosomal effect (ICE). The behaviour of the CA during meiosis may account for the infertility observed in this population. We studied chromosome segregation, ICE and meiotic defects in a variety of CA. In carriers of CA, we determined the segregation patterns of chromosomes involved in the abnormality.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Behavioral health care: Assessment, service planning, and total clinical outcomes management

https://cwslc.andornot.com/en/permalink/catalog111044
Lyons, John S., Weiner, Dana A. Kingston, NJ: Civic Research Institute , 2009.
Material Type
Book
Call Number
REF CC 600 LYO 2009
Availability
1 copy, 1 available
This book provides an approach for delivering more effective—and cost effective—behavioral health services. It offeres solutions to help improve the service delivery process, fine-tune behavioral health care needs assessments, match the level of care you provide to patients' needs and…
Author
Lyons, John S.
Weiner, Dana A.
Place of Publication
Kingston, NJ
Publisher
Civic Research Institute
Publication Date
2009
Physical Description
Hardcover: [534] p.
Subject
Behaviour Therapy. Behaviour Modification
Health Care Delivery Systems
Abstract
This book provides an approach for delivering more effective—and cost effective—behavioral health services. It offeres solutions to help improve the service delivery process, fine-tune behavioral health care needs assessments, match the level of care you provide to patients' needs and to retrieve better results.
ISBN
1887554696
Language
English
Material Type
Book
Call Number
REF CC 600 LYO 2009

Copies

Copy 1 BC Children's and Women's Study and Learning Commons Available
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Curriculum development in nursing education

https://cwslc.andornot.com/en/permalink/catalog112443
Iwasiw, Carroll L., Goldenberg, Dolly, Andrusyszyn, Mary-Anne. Sudbury, MA: Jones and Bartlett Publishers , 2009. 2nd ed.
Material Type
Book
Call Number
REF AA 75 IWA 2009
Availability
1 copy, 1 available
The second edition of this book has been completely revised and updated and includes an expanded focus on developing a context-relevant curriculum. A major determinant in any nursing education curriculum is the context in which the curriculum is developed and offered. This context is the profession…
Author
Iwasiw, Carroll L.
Goldenberg, Dolly
Andrusyszyn, Mary-Anne
Edition
2nd ed.
Place of Publication
Sudbury, MA
Publisher
Jones and Bartlett Publishers
Publication Date
2009
Physical Description
Softcover: 355 p.
Subject
Nursing. Registered Nurse. RN
Leadership/Coaching
Abstract
The second edition of this book has been completely revised and updated and includes an expanded focus on developing a context-relevant curriculum. A major determinant in any nursing education curriculum is the context in which the curriculum is developed and offered. This context is the professional, societal, health care, and educational situations to which the curriculum must respond, and is what makes each school's curriculum unique. This book helps nurse educators create a program of study that will meet the contextual needs of their individual setting.
Notes
RESTRICTED TO PHSA LEADERSHIP COACHING PARTICIPANTS ONLY.
Language
English
Material Type
Book
Call Number
REF AA 75 IWA 2009

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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The PIERS (Pre-eclampsia Integrated Estimate of RiSk) model : development of a valid outcome prediction model for pre-eclampsia.

https://cwslc.andornot.com/en/permalink/catalog113957
Menzies, Jennifer Marie. [Vancouver, BC?]: University of British Columbia , 2009.
Website
http://hdl.handle.net/2429/6844
Material Type
Thesis
Call Number
Thesis Shelf
Availability
1 copy, 1 available
This research responded to the need to define evidence-based criteria of maternal risk by developing a model - the Pre-eclampsia Integrated Estimate of RiSk (or PIERS) model ? that predicts a combined adverse maternal outcome (mortality and/or significant morbidities) within 48 hour of, and up to s…
Website
http://hdl.handle.net/2429/6844
Author
Menzies, Jennifer Marie
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2009
Subject
Faculty of Medicine
Theses
Abstract
This research responded to the need to define evidence-based criteria of maternal risk by developing a model - the Pre-eclampsia Integrated Estimate of RiSk (or PIERS) model ? that predicts a combined adverse maternal outcome (mortality and/or significant morbidities) within 48 hour of, and up to seven days after, admission with pre-eclampsia (study eligibility)
Language
English
Material Type
Thesis
Call Number
Thesis Shelf

Copies

Copy 1 BC Children's and Women's Study and Learning Commons Thesis Shelf Available
Websites
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Infusion Nursing:: An Evidence-Based Approach

https://cwslc.andornot.com/en/permalink/catalog125213
McGee, Steven R.;. Philadelphia: Elsevier , 2009. 3rd.
Material Type
Book
Call Number
REF WB 200 ALE 2009
Availability
1 copy, 1 available
With a new focus on evidence-based practice, the 3rd edition of this authoritative reference covers every aspect of infusion therapy and can be applied to any clinical setting. Completely updated content brings you the latest advances in equipment, technology, best practices, guidelines, and patien…
Author
McGee, Steven R.;
Edition
3rd
Place of Publication
Philadelphia
Publisher
Elsevier
Publication Date
2009
Physical Description
624 pp Hardcover
Subjects
Evidence-Based Medicine
Infusion nursing
Evidence Based
Abstract
With a new focus on evidence-based practice, the 3rd edition of this authoritative reference covers every aspect of infusion therapy and can be applied to any clinical setting. Completely updated content brings you the latest advances in equipment, technology, best practices, guidelines, and patient safety. Other key topics include quality management, ethical and legal issues, patient education, and financial considerations. Ideal as a practical clinical reference, this essential guide is also a perfect review tool for the CRNI examination.
ISBN
978-1416064107
Material Type
Book
Call Number
REF WB 200 ALE 2009

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
Images
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Clinical and endocrine responses to ovarian hyperstimulation in flare and and luteal gonadotropin-releasing hormone agonist (GnRHa) protocols

https://cwslc.andornot.com/en/permalink/catalog113958
Nguyen, Tuan-Anh T. [Vancouver, BC?]: University of British Columbia , 2008.
Website
http://hdl.handle.net/2429/1395
Material Type
Thesis
Call Number
Thesis Shelf
Due to the ?flare effect? associated with the flare protocol, variation in the degree of follicular maturation during stimulation may result in differences in follicle response as compared to the luteal protocol which is based on maximal pituitary suppression and synchronization of follicular matur…
Website
http://hdl.handle.net/2429/1395
Author
Nguyen, Tuan-Anh T
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2008
Subject
Faculty of Medicine
Theses
Abstract
Due to the ?flare effect? associated with the flare protocol, variation in the degree of follicular maturation during stimulation may result in differences in follicle response as compared to the luteal protocol which is based on maximal pituitary suppression and synchronization of follicular maturation. In this study, besides other methods, Anti-Mullerian Hormone (AMH), a novel marker for ovarian reserve, was used as a tool to evaluate the ovarian responsiveness to stimulation.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Aneuploidy and DNA fragmentation in morphologically abnormal sperm

https://cwslc.andornot.com/en/permalink/catalog113959
Tang, Steven Siu Yan. [Vancouver, BC?]: University of British Columbia , 2008.
Website
http://hdl.handle.net/2429/945
Material Type
Thesis
Call Number
Thesis Shelf
Intracytoplasmic sperm injection (ICSI) has been a successful assisted reproductive technique for men with severe male-factor infertility. However, ICSI requires the subjective selection of normal looking sperm, which does not preclude the transmission of genetically abnormal sperm. Correlation bet…
Website
http://hdl.handle.net/2429/945
Author
Tang, Steven Siu Yan
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2008
Subject
Faculty of Medicine
Theses
Abstract
Intracytoplasmic sperm injection (ICSI) has been a successful assisted reproductive technique for men with severe male-factor infertility. However, ICSI requires the subjective selection of normal looking sperm, which does not preclude the transmission of genetically abnormal sperm. Correlation between abnormal sperm morphology and chromosomal abnormalities has been suggested but not been conclusive and less is known about the connection between sperm morphology and DNA integrity. Sperm morphology will be evaluated on its ability to identify the level of chromosomal abnormalities or fragmented DNA in sperm. To further focus this investigation on sperm morphology, men with infertility isolated to abnormal sperm morphology (isolated teratozoopsermia) are examined.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Meiotic defects in infertile men

https://cwslc.andornot.com/en/permalink/catalog113960
Ferguson, Kyle Akira. [Vancouver, BC?]: University of British Columbia , 2008.
Website
http://hdl.handle.net/2429/1228
Material Type
Thesis
Call Number
Thesis Shelf
While the introduction of intracytoplasmic sperm injection (ICSI) has revolutionized the treatment of male infertility, concerns have been raised regarding the risk of chromosomal abnormalities in pregnancies derived from ICSI. Studies on sperm from infertile men have suggested that this population…
Website
http://hdl.handle.net/2429/1228
Author
Ferguson, Kyle Akira
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2008
Subject
Faculty of Medicine
Theses
Abstract
While the introduction of intracytoplasmic sperm injection (ICSI) has revolutionized the treatment of male infertility, concerns have been raised regarding the risk of chromosomal abnormalities in pregnancies derived from ICSI. Studies on sperm from infertile men have suggested that this population may produce higher rates of aneuploid sperm. Thus, we hypothesized that defects in early meiotic events may contribute to both male infertility and the production of aneuploid sperm.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Perinatal nursing: Professional development guidebook

https://cwslc.andornot.com/en/permalink/catalog108787
McDougall, Debbie, BC Women's Perinatal Educators. [Vancouver, BC?]: BC Women's Hospital + Health Centre , 2008.
Material Type
Book
Call Number
REF JC 500 MCD 2008
Availability
1 copy, 1 available
This guide provides a framework for competency-based education for perinatal nurses. It is adaptable to many perinatal nursing specialties and settings and provides practical information and tools to enable nurses to take charge of their orientation, ongoing education and continuing professional d…
Author
McDougall, Debbie
BC Women's Perinatal Educators
Place of Publication
[Vancouver, BC?]
Publisher
BC Women's Hospital + Health Centre
Publication Date
2008
Physical Description
3 ring binder: 410 pages; incl. 10 x 14 cm learning journal
Subject
Nursing. Registered Nurse. RN
Abstract
This guide provides a framework for competency-based education for perinatal nurses. It is adaptable to many perinatal nursing specialties and settings and provides practical information and tools to enable nurses to take charge of their orientation, ongoing education and continuing professional development. This comprehensive resource will help with orientation planning as well as the implementation of staff development programs. Perinatal competencies are articulated in the form of a CAPE tool (Competence Assessment, Planning and Evaluation) for basic, advanced and complex levels.
Language
English
Material Type
Book
Call Number
REF JC 500 MCD 2008

Copies

Copy 1 BC Children's and Women's Study and Learning Commons Missing Available
Images
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The developing human: Clinical oriented embryology

https://cwslc.andornot.com/en/permalink/catalog112676
Moore, Keith L., Persaud, T.V.N. Philadelphia, PA: Saunders Elsevier , 2008. 8th Ed.
Material Type
Book
Call Number
REF AB 55 MOO 2008
Availability
1 copy, 1 available
This text examines all aspects of human development, emphasizing both basic concepts and relevant clinical problems. The book presents a week-by-week and stage-by-stage view of how fetal organs and systems develop, why and when birth defects occur, and what roles the placenta and fetal membranes pl…
Author
Moore, Keith L.
Persaud, T.V.N.
Edition
8th Ed.
Place of Publication
Philadelphia, PA
Publisher
Saunders Elsevier
Publication Date
2008
Physical Description
Softcover: 522 pages
Subject
Embryology
UBC MD Undergrad
Abstract
This text examines all aspects of human development, emphasizing both basic concepts and relevant clinical problems. The book presents a week-by-week and stage-by-stage view of how fetal organs and systems develop, why and when birth defects occur, and what roles the placenta and fetal membranes play in development.
ISBN
9781416037064
Language
English
Material Type
Book
Call Number
REF AB 55 MOO 2008

Copies

Copy 1 BC Children's and Women's Study and Learning Commons MISSING Available
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Health behavior and health education

https://cwslc.andornot.com/en/permalink/catalog113881
Glanz, Karen, Rimer, Barbara, Viswanath, K. Jossey-Bass , 2008. 4th ed.
Material Type
Book
Call Number
REF AB 70 GLA 2008
Availability
1 copy, 1 available
Health Behavior and Health Education: Theory, Research, and Practice provides a comprehensive, highly accessible, and in-depth analysis of health behavior theories that are most relevant to health education. This essential resource includes the most current information on theory, research, and prac…
Author
Glanz, Karen
Rimer, Barbara
Viswanath, K.
Edition
4th ed.
Publisher
Jossey-Bass
Publication Date
2008
Physical Description
Hardcover, 592 p.
Abstract
Health Behavior and Health Education: Theory, Research, and Practice provides a comprehensive, highly accessible, and in-depth analysis of health behavior theories that are most relevant to health education. This essential resource includes the most current information on theory, research, and practice at individual, interpersonal, and community and group levels. This edition includes substantial new content on current and emerging theories of health communication, e-health, culturally diverse communities, health promotion, the impact of stress, the importance of networks and community, social marketing, and evaluation.
ISBN
9780787996147
Language
English
Material Type
Book
Call Number
REF AB 70 GLA 2008

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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Learning healthcare system: Workshop summary (IOM Roundtable on Evidence-Based Medicine)

https://cwslc.andornot.com/en/permalink/catalog113231
Olsen, LeighAnne;, Aisner, Dara;, McGinnis, J. Michael (Eds). Washington, DC: National Academies Press , 2007.
Website
http://www.nap.edu/catalog.php?record_id=11903
Material Type
Online
This book considers how health care is structured to develop and to apply evidence--from health profession training and infrastructure development to advances in research methodology, patient engagement, payment schemes, and measurement--and highlights opportunities for the creation of a sustainabl…
Website
http://www.nap.edu/catalog.php?record_id=11903
Website Notes
Read online or download as PDF.
Author
Olsen, LeighAnne;
Aisner, Dara;
McGinnis, J. Michael (Eds).
Place of Publication
Washington, DC
Publisher
National Academies Press
Publication Date
2007
Physical Description
374 pages, 2 MB PDF file.
Subject
Health Care Delivery Systems
Evidence-Based Medicine
Abstract
This book considers how health care is structured to develop and to apply evidence--from health profession training and infrastructure development to advances in research methodology, patient engagement, payment schemes, and measurement--and highlights opportunities for the creation of a sustainable learning health care system that gets the right care to people when they need it and then captures the results for improvement. This book will be of primary interest to hospital and insurance industry administrators, health care providers, those who train and educate health workers, researchers, and policymakers.
ISBN
978-0-309-10300-8
Language
English
Material Type
Online
Websites
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Roles of Confined Placental Mosaicism (CPM) and H19/IGF2 imprinting in pregnancies derived from intracytoplasmic sperm injection (ICSI)

https://cwslc.andornot.com/en/permalink/catalog113961
Hatakeyama, Chiho. [Vancouver, BC?]: University of British Columbia , 2007.
Website
http://hdl.handle.net/2429/32719
Material Type
Thesis
Call Number
Thesis Shelf
In contrast to the success of ICSI in treating male infertility, concerns have been raised about the health outcomes of the children conceived through this procedure. Cohort studies have shown that the ICSI population has an increase in low birth weight (LBW), birth defects, chromosomal abnormaliti…
Website
http://hdl.handle.net/2429/32719
Author
Hatakeyama, Chiho
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2007
Subject
Faculty of Medicine
Theses
Abstract
In contrast to the success of ICSI in treating male infertility, concerns have been raised about the health outcomes of the children conceived through this procedure. Cohort studies have shown that the ICSI population has an increase in low birth weight (LBW), birth defects, chromosomal abnormalities, and imprinting disorders. However, the underlying causes remain unknown.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
Show Less

Recombinant human activated protein C as a therapy for pre-eclampsia

https://cwslc.andornot.com/en/permalink/catalog113962
Peng, Gang. [Vancouver, BC?]: University of British Columbia , 2007.
Website
http://hdl.handle.net/2429/32051
Material Type
Thesis
Call Number
Thesis Shelf
Pre-eclampsia remains one of the most common causes of maternal mortality in the developed world, and we still have no known effective prophylaxis and proven modifiers. The recent successful clinical trial of recombinant human activated protein C (rhAPC) in the management of SIRS (systemic inflamma…
Website
http://hdl.handle.net/2429/32051
Author
Peng, Gang
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2007
Subject
Faculty of Medicine
Theses
Abstract
Pre-eclampsia remains one of the most common causes of maternal mortality in the developed world, and we still have no known effective prophylaxis and proven modifiers. The recent successful clinical trial of recombinant human activated protein C (rhAPC) in the management of SIRS (systemic inflammatory response syndrome) has drawn attention to the possible use of this medicine for other conditions. Pre-eclampsia, has remarkable similarity to SIRS and may be such a condition.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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The handbook of leadership development evaluation

https://cwslc.andornot.com/en/permalink/catalog109809
Hannum, Kelly (Editor), Martineau, Jennifer W. (Editor), Reinelt, Claire (Editor). San Francisco, CA: Jossey-Bass , 2007. 1st ed.
Material Type
Book
Call Number
REF AA 500 HAN 2007
Availability
1 copy, 1 available
With the increase in the number of organizational leadership development programs, there is a pressing need for evaluation to answer important questions, improve practice, and inform decisions. The Handbook is a comprehensive resource filled with examples, tools, and the most innovative models and …
Author
Hannum, Kelly (Editor)
Martineau, Jennifer W. (Editor)
Reinelt, Claire (Editor)
Edition
1st ed.
Place of Publication
San Francisco, CA
Publisher
Jossey-Bass
Publication Date
2007
Physical Description
Paperback, 632 p.
Subject
Administration
Program Evaluation
Abstract
With the increase in the number of organizational leadership development programs, there is a pressing need for evaluation to answer important questions, improve practice, and inform decisions. The Handbook is a comprehensive resource filled with examples, tools, and the most innovative models and approaches designed to evaluate leadership development in a variety of settings. It will help you answer the most common questions about leadership development efforts, including:
What difference does leadership development make?
What development and support strategies work best to enhance leadership?
Is the time and money spent on leadership development worthwhile?
What outcomes can be expected from leadership development?
How can leadership development efforts be sustained?
Notes
For PHSA Staff only
ISBN
978-0-7879-8217-1
Language
English
Material Type
Book
Call Number
REF AA 500 HAN 2007

Copies

Copy 1 BC Children's and Women's Study and Learning Commons Available
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Teaching nursing: Developing a student-centered learning environment

https://cwslc.andornot.com/en/permalink/catalog112442
Young, Lynne E., Paterson, Barbara L. Philadelphia, PA: Lippincott Williams & Wilkins , 2007.
Material Type
Book
Call Number
REF AA 75 YOU 2007
Availability
1 copy, 1 available
This book will help you provide today's diverse student population with the skills they need to become creative, critical, and cooperative problem solvers. Each chapter includes opening scenarios (to help link theory to practice), learning activities (to spark interest in key topics while encouragi…
Author
Young, Lynne E.
Paterson, Barbara L.
Place of Publication
Philadelphia, PA
Publisher
Lippincott Williams & Wilkins
Publication Date
2007
Physical Description
Softcover: 600 p.
Subject
Nursing. Registered Nurse. RN
Leadership/Coaching
Abstract
This book will help you provide today's diverse student population with the skills they need to become creative, critical, and cooperative problem solvers. Each chapter includes opening scenarios (to help link theory to practice), learning activities (to spark interest in key topics while encouraging further exploration of the concepts presented in each chapter) and resources for educators (to provide teaching ideas, tools, and strategies).
Notes
RESTRICTED TO PHSA LEADERSHIP COACHING PARTICIPANTS ONLY.
Language
English
Material Type
Book
Call Number
REF AA 75 YOU 2007

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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Textbook of Pediatric Emergency Procedures

https://cwslc.andornot.com/en/permalink/catalog125197
King, Christopher, Henretig, Fred, King, Brent, Loiselle, John. Philadelphia, PA: Wolters Kluwer , 2007. 2nd.
Material Type
Book
Call Number
REF EB 800 KIN 2007
Availability
1 copy, 1 available
Widely acclaimed for its outstanding step-by-step illustrations, comprehensive coverage, and reader-friendly format, Textbook of Pediatric Emergency Procedures is now in its thoroughly updated Second Edition. In 137 chapters, the book provides clear, complete instructions on every emergency medicin…
Author
King, Christopher
Henretig, Fred
King, Brent
Loiselle, John
Edition
2nd
Place of Publication
Philadelphia, PA
Publisher
Wolters Kluwer
Publication Date
2007
Physical Description
Hardcover, 1344 pp
Subjects
Pediatrics
Emergency Procedures
Subject
Emergency Medicine
Leadership/Coaching
Abstract
Widely acclaimed for its outstanding step-by-step illustrations, comprehensive coverage, and reader-friendly format, Textbook of Pediatric Emergency Procedures is now in its thoroughly updated Second Edition. In 137 chapters, the book provides clear, complete instructions on every emergency medicine procedure performed on infants, children, and adolescents. More than 1,000 detailed drawings, most in two-color, show howto perform each procedure. This edition includes a new chapter on new technologies and techniques for managing the difficult airway. Other new topics include use of tissue adhesives in laceration repair, focused abdominal sonography for trauma (FAST), management of priapism, reimplanting an avulsed permanent tooth, use of automatic external defibrillators, and procedures related to bioterrorism.
ISBN
978-0781753869
Language
English
Material Type
Book
Call Number
REF EB 800 KIN 2007

Copies

Copy 1 BC Children's and Women's Study and Learning Commons REF Available
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Expression and function of HOXA genes in the normal ovary and ovarian carcinoma

https://cwslc.andornot.com/en/permalink/catalog113963
Ota, Takayo. [Vancouver, BC?]: University of British Columbia , 2006.
Website
http://hdl.handle.net/2429/30974
Material Type
Thesis
Call Number
Thesis Shelf
Homeobox genes, which code for families of transcription factors, act at the top of genetic hierarchies. HOX genes specify positional identity during development, and in adult tissues, regulate differentiation and proliferation. Most ovarian carcinomas are derived from the ovarian surface epitheliu…
Website
http://hdl.handle.net/2429/30974
Author
Ota, Takayo
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2006
Subject
Faculty of Medicine
Theses
Abstract
Homeobox genes, which code for families of transcription factors, act at the top of genetic hierarchies. HOX genes specify positional identity during development, and in adult tissues, regulate differentiation and proliferation. Most ovarian carcinomas are derived from the ovarian surface epithelium (OSE). In contrast to other carcinomas, OSE differentiates further with neoplastic progression and acquires Mtillerian duct-derived epithelial properties. I tested the hypothesis that growth and differentiation in ovarian carcinogenesis are regulated by HOX genes.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Implications of BRCA-loss phenotype in epithelial ovarian carcinoma

https://cwslc.andornot.com/en/permalink/catalog113964
Press, Joshua Zephyr. [Vancouver, BC?]: University of British Columbia , 2006.
Website
http://hdl.handle.net/2429/32234
Material Type
Thesis
Call Number
Thesis Shelf
Loss of BRCA1/BRCA2 function through genetic or epigenetic mechanisms is common in epithelial ovarian carcinomas (EOC), but because there are multiple potential mechanisms of loss, the overall frequency is unknown. We characterized loss of BRCA1/BRCA2 at the DNA, RNA and protein level from an unsel…
Website
http://hdl.handle.net/2429/32234
Author
Press, Joshua Zephyr
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2006
Subject
Faculty of Medicine
Theses
Abstract
Loss of BRCA1/BRCA2 function through genetic or epigenetic mechanisms is common in epithelial ovarian carcinomas (EOC), but because there are multiple potential mechanisms of loss, the overall frequency is unknown. We characterized loss of BRCA1/BRCA2 at the DNA, RNA and protein level from an unselected, consecutive series 49 non-mucinous, invasive EOC. BRCAl-loss was found in 21/49 tumors (43%).
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Gonadotropins and leptin : the role and molecular mechanism in normal and neoplastic ovarian epithelium cells

https://cwslc.andornot.com/en/permalink/catalog113965
Choi, Jung-Hye. [Vancouver, BC?]: University of British Columbia , 2006.
Website
http://hdl.handle.net/2429/18509
Material Type
Thesis
Call Number
Thesis Shelf
Ovarian cancer is the sixth most common cancer and the fifth leading cause of cancer-related death among women in developed countries. There is increasing evidence suggesting that the hormonal environment of the normal ovarian surface epithelium (OSE) and ovarian epithelial cancer (OEC) cells is as…
Website
http://hdl.handle.net/2429/18509
Author
Choi, Jung-Hye
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
2006
Subject
Faculty of Medicine
Theses
Abstract
Ovarian cancer is the sixth most common cancer and the fifth leading cause of cancer-related death among women in developed countries. There is increasing evidence suggesting that the hormonal environment of the normal ovarian surface epithelium (OSE) and ovarian epithelial cancer (OEC) cells is associated with the development and progression of ovarian cancer. Exposure to excess gonadotropins and leptin, related to menopause or infertility therapy and obesity, respectively, has been implicated as a risk factor for ovarian cancer.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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20 records – page 1 of 1.