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Intracytoplasmic sperm injection (ICSI) has been a successful assisted reproductive technique for men with severe male-factor infertility. However, ICSI requires the subjective selection of normal looking sperm, which does not preclude the transmission of genetically abnormal sperm. Correlation bet…
This book provides an approach for delivering more effective—and cost effective—behavioral health services. It offeres solutions to help improve the service delivery process, fine-tune behavioral health care needs assessments, match the level of care you provide to patients' needs and…
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Remodeling of the endometrial extracellular matrix, which occurs during the early stages of pregnancy in the human, is mediated by the temporal expression of urokinase-type plasminogen activator (uPA) and matrix metalloproteinases (MMP) in both the maternal and fetal compartments and counterbalance…
Volume 1 of this 7th edition contains 36 new chapters and full-color figures and photographs. Compared with the rather limited color-plate photographs in the sixth edition, the color photographs, figures, and tables in each chapter significantly enhance the new text. Informative chapters on the fou…
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Volume 2 of this 7th edition contains 36 new chapters and full-color figures and photographs. Compared with the rather limited color-plate photographs in the sixth edition, the color photographs, figures, and tables in each chapter significantly enhance the new text. Informative chapters on the fou…
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Male carriers of chromosomal abnormalities (CA) are more frequent in the infertile population. These men have higher levels of sperm aneuploidy due to the aberrant segregation of the chromosomes involved in the abnormality. The presence of a CA may also influence the segregation of other chromosome…
Due to the ?flare effect? associated with the flare protocol, variation in the degree of follicular maturation during stimulation may result in differences in follicle response as compared to the luteal protocol which is based on maximal pituitary suppression and synchronization of follicular matur…
The second edition of this book has been completely revised and updated and includes an expanded focus on developing a context-relevant curriculum. A major determinant in any nursing education curriculum is the context in which the curriculum is developed and offered. This context is the profession…
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This text examines all aspects of human development, emphasizing both basic concepts and relevant clinical problems. The book presents a week-by-week and stage-by-stage view of how fetal organs and systems develop, why and when birth defects occur, and what roles the placenta and fetal membranes pl…
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Nursing programs everywhere are looking to evidence-based practice (EBP) with renewed enthusiasm. This is often sparked by an effort to elevate clinical quality and improve outcomes, but nursing programs also turn to EBPs as a way to reinvigorate the practice environment. EBP de-emphasizes ritual o…
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Homeobox genes, which code for families of transcription factors, act at the top of genetic hierarchies. HOX genes specify positional identity during development, and in adult tissues, regulate differentiation and proliferation. Most ovarian carcinomas are derived from the ovarian surface epitheliu…
The association between subsets of male infertility, oligoasthenoteratozoospermia (OAT), obstructive azoospermic (OA), non-obstructive azoospermia (NOA), and increased risk of having chromosomal abnormalities in the sperm has not been investigated. Chromosomal aneuploidy in sperm will be systematic…
Ovarian cancer is the sixth most common cancer and the fifth leading cause of cancer-related death among women in developed countries. There is increasing evidence suggesting that the hormonal environment of the normal ovarian surface epithelium (OSE) and ovarian epithelial cancer (OEC) cells is as…
This comprehensive guide provides educators with the resources needed to implement a Preceptor Development Program in your organization. A series of six workshops, each four hours or less, addresses the learning needs of both beginning and experienced nurse preceptors, learners and hospital staff s…
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With the increase in the number of organizational leadership development programs, there is a pressing need for evaluation to answer important questions, improve practice, and inform decisions. The Handbook is a comprehensive resource filled with examples, tools, and the most innovative models and …
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Table of contents:; I. PHENOMENOLOGY OF THE TIC DISORDER; 1. Motor and Vocal Tics 1; Stanley Fahn; 2. Premonitory ("Sensory") Experiences 15; Tamara M. Pringsheim and Anthony E. Lang; 3. The Natural History of Gilles de la Tourette Syndrom…
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Health Behavior and Health Education: Theory, Research, and Practice provides a comprehensive, highly accessible, and in-depth analysis of health behavior theories that are most relevant to health education. This essential resource includes the most current information on theory, research, and prac…
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Loss of BRCA1/BRCA2 function through genetic or epigenetic mechanisms is common in epithelial ovarian carcinomas (EOC), but because there are multiple potential mechanisms of loss, the overall frequency is unknown. We characterized loss of BRCA1/BRCA2 at the DNA, RNA and protein level from an unsel…