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Confidently Perform Accurate, Efficient, and Effective Physical Examinations.; Master the techniques for successful physical examinations with the #1 choice for complete, authoritative guidance. This highly regarded text in book-only format includes fully-illustrated, step-by-step techniques that o…
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A point-of-care guide for internal medicine trainees; When students and residents begin a new rotation in internal medicine, they often start from scratch, relying on their own research to prepare for consultations. What questions are crucial during history taking? What should the physical examinat…
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For more than 40 years,West's Respiratory Physiology: The Essentialshas remained a critical resource for medical and allied health students learning the basics of respiratory physiology as well as an effective, quick review for residents and fellows in pulmonary medicine, critical care, anesthesiol…
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This worldwide bestseller offers simple guidance for building the kind of open and trusting relationships vital for tackling global systemic challenges and developing adaptive, innovative organizations?over 200,000 copies sold and translated into seventeen languages!; We live, say Edgar and Peter S…
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Established for more than 75 years,The Washington Manual of Medical Therapeutics, 36th Edition, provides concise, high-yield content that reflects today's fast-changing advances in medical technology and therapeutics. In one convenient, portable resource, you'll find complete coverage of every area…
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Harwood-Nuss' Clinical Practice of Emergency Medicine presents a clinically focused and evidence-based summary of emergency medicine. Chapters are templated to include the clinical presentation, differential diagnosis, evaluation, management and disposition, with highlighted critical interventions …
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Ovarian cancer is the most lethal gynecological cancer in the Western world, but comparatively little is known about its development. Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e. the mesothelium covering the ovary, but experimental evidence fo…
It is well established that LH action is mediated primarily by adenylate cyclase/cAMP. Conversely, the role of inositol phosphate/calcium in LH signalling has only recently been investigated. We examined the effects of gonadotrophins on intracellular calcium mobilisation in HEK293 cells transiently…
The purpose of this research was to examine hindlimb blood flow and oxygen supply in the late-gestation fetal lamb under normal and pathophysiological conditions. Although the carcass, or non-visceral tissue, accounts for a large proportion of fetal weight and oxygen demand, it has received little …
A comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics.
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A comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics.
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A comprehensive, authoritative and timely knowledgebase of human genes and genetic disorders compiled to support human genetics research and education and the practice of clinical genetics.
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These studies examined the effects of prostaglandin-F[sub 2a] (PGF[sub 2a]) on progesterone and 178-estradiol (estradiol) production, as well as DNA and PGF[sub 2a]-receptor (PGF[sub 2a]-R) mRNA levels, in the human granulosa-luteal cell (GLC). Additionally, the interactions of PGF[sub 2a] with hum…
The studies undertaken herewithin sought to characterize the pattern of regulation of the gonadotrophin-releasing hormone receptor (GnRH-R) mRNA levels in the rat ovary. The demonstration of gonadotrophin-releasing hormone (GnRH) transcripts in steroidproducing and steroid-dependent tissues suggest…
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type…
Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation…
The placenta is an important endocrine organ producing large amounts of steroid and protein hormones which are released into the maternal and fetal circulations. Moreover, it has a very high metabolic rate and consumes a significant proportion of the oxygen and glucose delivered to the uterus and i…
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling sti…
In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fai…
This thesis investigated the expression and regulation of cytochrome P450s, aromatase (P450arom) and cholesterol side chain cleavage (P450scc) enzyme mRNAs in human granulosa-luteal cells using reverse transcription-polymerase chain reaction (RT-PCR). The two enzymes are instrumental in steroid hor…