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Bates' guide to physical examination and history taking

https://cwslc.andornot.com/en/permalink/catalog123792
Bickley, Lynn S., Szilagyi, Peter G. Philadelphia, PA: Lippincott Williams & Wilkins , 2023. 13th Ed.
Material Type
Book
Call Number
REF FA 100 BIC 2023
Availability
1 copy, 1 available
Confidently Perform Accurate, Efficient, and Effective Physical Examinations.; Master the techniques for successful physical examinations with the #1 choice for complete, authoritative guidance. This highly regarded text in book-only format includes fully-illustrated, step-by-step techniques that o…
Author
Bickley, Lynn S.
Szilagyi, Peter G.
Edition
13th Ed.
Place of Publication
Philadelphia, PA
Publisher
Lippincott Williams & Wilkins
Publication Date
2023
Physical Description
Hardcover: 1024 p.
Subject
General Medicine
Diagnostic Tests/Procedures. Physical Diagnosis
UBC MD Undergrad
Abstract
Confidently Perform Accurate, Efficient, and Effective Physical Examinations.
Master the techniques for successful physical examinations with the #1 choice for complete, authoritative guidance. This highly regarded text in book-only format includes fully-illustrated, step-by-step techniques that outline the correct performance of the physical examination and an easy-to-follow two-column format that correlates examination techniques on the left and abnormalities (clearly indicated in red) with differential diagnoses on the right.
ISBN
978-1975210533
Language
English
Material Type
Book
Call Number
REF FA 100 BIC 2023

Copies

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Lange: Current medical diagnosis and treatment

https://cwslc.andornot.com/en/permalink/catalog123804
Papadakis, Maxine A. (ed.), McPhee, Stephen J. (ed.), Rabow, Michael W. (ed.). [Toronto, ON]: McGraw Hill Lange , 2020. 59th ed.
Material Type
Book
Call Number
REF FA 140 PAP 2020
Availability
1 copy, 1 available
CURRENT Medical Diagnosis & Treatment is the most comprehensive, reliable, and timely reference available to answer common questions that arise in everyday clinical practice. Written by clinicians renowned in their respective fields, this trusted classic offers expert advice on all aspects of outpa…
Author
Papadakis, Maxine A. (ed.)
McPhee, Stephen J. (ed.)
Rabow, Michael W. (ed.)
Edition
59th ed.
Place of Publication
[Toronto, ON]
Publisher
McGraw Hill Lange
Publication Date
2020
Physical Description
Softcover: 1915 p.
Subject
Diagnostic Tests/Procedures. Physical Diagnosis
Symptoms
UBC MD Undergrad
Abstract
CURRENT Medical Diagnosis & Treatment is the most comprehensive, reliable, and timely reference available to answer common questions that arise in everyday clinical practice. Written by clinicians renowned in their respective fields, this trusted classic offers expert advice on all aspects of outpatient and inpatient medical care. You?ll find authoritative, evidence-based coverage of more than 1,000 diseases and disorders including concise, yet thorough synopsis of diagnosis and treatment. Presented in full-color, this single source reference has been fully updated with the latest developments and breakthroughs in medicine, guidelines, references, drug prices, and more.
ISBN
9781-260-45528-1
Language
English
Material Type
Book
Call Number
REF FA 140 PAP 2020

Copies

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Vancouver Notes for Internal Medicine: High-Yield Consult Guides

https://cwslc.andornot.com/en/permalink/catalog125185
Vancouver, BC: Brush Education , 2022.
Material Type
Book
Call Number
REF AB 22 TAN 2022
Availability
2 copies, 2 available
A point-of-care guide for internal medicine trainees; When students and residents begin a new rotation in internal medicine, they often start from scratch, relying on their own research to prepare for consultations. What questions are crucial during history taking? What should the physical examinat…
Editor
Tang, Brandon
Zhuang, Meiying
Tessaro, James
Place of Publication
Vancouver, BC
Publisher
Brush Education
Publication Date
2022
Physical Description
424 pp
Subjects
Internal Medicine
Subject
Medical Directories. Resource Guides
UBC MD Undergrad
Abstract
A point-of-care guide for internal medicine trainees
When students and residents begin a new rotation in internal medicine, they often start from scratch, relying on their own research to prepare for consultations. What questions are crucial during history taking? What should the physical examination and investigations focus on? What should the consultation write-up include? Now, physician learners can turn to Vancouver Notes for Internal Medicine for guidance on conducting consultations in each of the core internal medicine subspecialties.
Vancouver Notes provides learners with an organized approach to common presentations in internal medicine. For each subspecialty, it lays out the process for identifying key information and communicating findings and management recommendations to a patient?s health-care team. Developed through the efforts of more than 90 resident physicians and faculty members at the University of British Columbia, Vancouver Notes combines valuable clinical pearls in a single, accessible resource to give students and residents the tools they need to succeed from day one.
ISBN
978-1550598995
Language
English
Material Type
Book
Call Number
REF AB 22 TAN 2022

Copies

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Fighting for a Hand to Hold:: Confronting Medical Colonialism against Indigenous Children in Canada

https://cwslc.andornot.com/en/permalink/catalog123859
Shaeen-Hussain, Samir. Quebec: McGill Queen University Press , 2020.
Material Type
Book
Call Number
ET 100 SHA 2020
Availability
1 copy, 1 available
Launched by healthcare providers in January 2018, the #aHand2Hold campaign confronted the Quebec government's practice of separating children from their families during medical evacuation airlifts, which disproportionately affected remote and northern Indigenous communities. Pediatric emergency phy…
Author
Shaeen-Hussain, Samir
Place of Publication
Quebec
Publisher
McGill Queen University Press
Publication Date
2020
Physical Description
Paperback 326pp
Subject
Diversity
Health
Ethics
health inequities
Indigenous
Abstract
Launched by healthcare providers in January 2018, the #aHand2Hold campaign confronted the Quebec government's practice of separating children from their families during medical evacuation airlifts, which disproportionately affected remote and northern Indigenous communities. Pediatric emergency physician Samir Shaheen-Hussain's captivating narrative of this successful campaign, which garnered unprecedented public attention and media coverage, seeks to answer lingering questions about why such a cruel practice remained in place for so long. In doing so it serves as an indispensable case study of contemporary medical colonialism in Quebec. Fighting for a Hand to Hold exposes the medical establishment's role in the displacement, colonization, and genocide of Indigenous peoples in Canada. Through meticulously gathered government documentation, historical scholarship, media reports, public inquiries, and personal testimonies, Shaheen-Hussain connects the draconian medevac practice with often-disregarded crimes and medical violence inflicted specifically on Indigenous children. This devastating history and ongoing medical colonialism prevent Indigenous communities from attaining internationally recognized measures of health and social well-being because of the pervasive, systemic anti-Indigenous racism that persists in the Canadian public health care system - and in settler society at large. Shaheen-Hussain's unique perspective combines his experience as a frontline pediatrician with his long-standing involvement in anti-authoritarian social justice movements. Sparked by the indifference and callousness of those in power, this book draws on the innovative work of Indigenous scholars and activists to conclude that a broader decolonization struggle calling for reparations, land reclamation, and self-determination for Indigenous peoples is critical to achieve reconciliation in Canada.
ISBN
9780-2280-03601
Material Type
Book
Call Number
ET 100 SHA 2020

Copies

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BLS Basic life support: Provider manual

https://cwslc.andornot.com/en/permalink/catalog123201
American Heart Association, Heart & Stroke Foundation. [Ottawa, ON]: American Heart Association | Heart & Stroke Foundation , 2020.
Material Type
Book
Call Number
REF EB 270 AHA 2020
Availability
25 copies, 17 available
The Basic Life Support (BLS) for Healthcare Providers (HCP) is a classroom course that is designed to teach a variety of healthcare professionals how to recognize a number of life-threatening emergencies, how to provide CPR, how to use an AED and how to relieve choking in a safe, timely and effecti…
Website Notes
Click link to see Table of Contents
Corporate Author
American Heart Association
Heart & Stroke Foundation
Place of Publication
[Ottawa, ON]
Publisher
American Heart Association
Heart & Stroke Foundation
Publication Date
2020
Physical Description
Paperback: (112 p.: ill.).
Subject
Cardiopulmonary Resuscitation. CPR
First Aid
CPR
Certification
Abstract
The Basic Life Support (BLS) for Healthcare Providers (HCP) is a classroom course that is designed to teach a variety of healthcare professionals how to recognize a number of life-threatening emergencies, how to provide CPR, how to use an AED and how to relieve choking in a safe, timely and effective manner.
ISBN
9781988892603
Language
English
Material Type
Book
Call Number
REF EB 270 AHA 2020

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Neonatal Resuscitation Textbook (NRP): Provider Manual

https://cwslc.andornot.com/en/permalink/catalog123322
Weiner, Gary M., Zaichkin, Jeanette, Kattwinkel, John. Elk Grove Village, IL: American Academy of Pediatrics , 2021. 8th.
Material Type
Book
Call Number
REF EB 800 NEO 2021
Availability
71 copies, 45 available
The Neonatal Resuscitation Program (NRP) is an educational program jointly sponsored with the American Heart Association (AHA). The course conveys an evidence-based approach to care of the newborn at birth and facilitates effective team-based care for healthcare professionals who care for newborns …
Author
Weiner, Gary M.
Zaichkin, Jeanette
Kattwinkel, John
Edition
8th
Place of Publication
Elk Grove Village, IL
Publisher
American Academy of Pediatrics
Publication Date
2021
Physical Description
Paperback, 361 p., ill
Subject
Neonatal Assessment
First Aid
Nursing
Abstract
The Neonatal Resuscitation Program (NRP) is an educational program jointly sponsored with the American Heart Association (AHA). The course conveys an evidence-based approach to care of the newborn at birth and facilitates effective team-based care for healthcare professionals who care for newborns at the time of delivery.
New in the 8th edition:
Key Points at the beginning of each lesson.
Quick response (QR) codes that enable the reader to view short videos about the topic on their mobile device.
Lesson Review Questions grouped together at the end of each lesson.
Quality Improvement Opportunities and Frequently Asked Questions in each lesson.
New sections in Lesson 10 (Special Considerations) about resuscitation of the newborn with a myelomeningocele or an abdominal wall defect.
Three Supplemental Lessons (Improving Resuscitation Team Performance, Resuscitation Outside the Delivery Room, and Bringing Quality Improvement to Your Resuscitation Team) that all NRP users to enhance their resuscitation knowledge and performance.
ISBN
9781610025249
Language
English
Material Type
Book
Call Number
REF EB 800 NEO 2021

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The developing human: Clinical oriented embryology

https://cwslc.andornot.com/en/permalink/catalog123798
Moore, Keith L., Persaud, T.V.N. Philadelphia, PA: Saunders Elsevier , 2020. 11th Ed.
Material Type
Book
Call Number
REF AB 55 MOO 2020
Availability
1 copy, 1 available
Extensively revised toincorporate recent research and current clinical practice ,The Developing Human: Clinically Oriented Embryology, 11th Edition,covers all aspects of normal and abnormal embryonic and fetal development. In a clear, concise manner and lavishly illustrated throughout, this textboo…
Author
Moore, Keith L.
Persaud, T.V.N.
Edition
11th Ed.
Place of Publication
Philadelphia, PA
Publisher
Saunders Elsevier
Publication Date
2020
Physical Description
Softcover: 503 pages
Subject
Embryology
UBC MD Undergrad
Abstract
Extensively revised toincorporate recent research and current clinical practice ,The Developing Human: Clinically Oriented Embryology, 11th Edition,covers all aspects of normal and abnormal embryonic and fetal development. In a clear, concise manner and lavishly illustrated throughout, this textbook is designed to successfully meet the needs of medical and health sciences profession students, as well as those in graduate programs. It provides aneasy-to-digest, comprehensive review of what can be a complex and challenging subject .BONUS online features such asmultiple-choice questions and narrated animations further support student success.
ISBN
9780-323-611541
Language
English
Material Type
Book
Call Number
REF AB 55 MOO 2020

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Pediatric advanced life support (PALS): Provider manual

https://cwslc.andornot.com/en/permalink/catalog123835
Chameides, Leon (ed.), Samson, Ricardo A. (ed.), Schexnayder, Stephen M. (ed.), et all. [Canada]: American Heart Association , 2020.
Material Type
Book
Call Number
REF EB 100 PAL 2020
Availability
26 copies, 13 available
The Pediatric Advanced Life Support (PALS) Provider Course is designed for healthcare providers who initiate and direct basic through advanced life support. Course concepts are designed to be used throughout the stabilization and transport phases for both in-hospital and out-of-hospital pediatric e…
Author
Chameides, Leon (ed.)
Samson, Ricardo A. (ed.)
Schexnayder, Stephen M. (ed.), et all.
Corporate Author
Heart & Stroke Foundation
Place of Publication
[Canada]
Publisher
American Heart Association
Publication Date
2020
Physical Description
Paperback, 332 p.
Subject
First Aid
Certification
Abstract
The Pediatric Advanced Life Support (PALS) Provider Course is designed for healthcare providers who initiate and direct basic through advanced life support. Course concepts are designed to be used throughout the stabilization and transport phases for both in-hospital and out-of-hospital pediatric emergencies. This course aims to increase your skills in the evaluation and management of an infant or child with respiratory compromise, circulatory compromise, or cardiac arrest.
ISBN
9781-988892-900
Language
English
Material Type
Book
Call Number
REF EB 100 PAL 2020

Copies

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Advanced cardiovascular life support (ACLS): Provider manual

https://cwslc.andornot.com/en/permalink/catalog123903
Heart & Stroke Foundation. [United States of America]: American Heart Association , 2020.
Material Type
Book
Call Number
REF EB 100 ACL 2020
Availability
15 copies, 12 available
Advanced Cardiovascular Life Support (ACLS) courses provide critical training to Canadian healthcare professionals. The Heart & Stroke ACLS course has been updated to reflect new science from the 2020 Guidelines Update for CPR and Emergency Cardiovascular Care (2020 Guidelines for CPR and ECC).; AC…
Corporate Author
Heart & Stroke Foundation
Place of Publication
[United States of America]
Publisher
American Heart Association
Publication Date
2020
Physical Description
Paperback, 202 pp
Subject
First Aid
CPR
Certification
Abstract
Advanced Cardiovascular Life Support (ACLS) courses provide critical training to Canadian healthcare professionals. The Heart & Stroke ACLS course has been updated to reflect new science from the 2020 Guidelines Update for CPR and Emergency Cardiovascular Care (2020 Guidelines for CPR and ECC).
ACLS builds on the foundation of basic life support (BLS) skills, emphasizing the importance of continuous, high-quality CPR. This advanced course highlights the importance of preventing cardiac arrest, high-performance team dynamics and communication, systems of care, recognition and intervention of cardiopulmonary arrest, immediate post-cardiac arrest, acute dysrhythmia, stroke, and acute coronary syndromes.
The ACLS Provider Manual is designed for a single user and is required for all students taking an ACLS course. Students will use this book to progress through the course and as a reference tool before and after the classroom session.
ISBN
9781-988892-726
Language
English
Material Type
Book
Call Number
REF EB 100 ACL 2020

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E-cadherin promotes tumorigenicity in human ovarian surface epithelium

https://cwslc.andornot.com/en/permalink/catalog113975
Ong, Aldrich Dixon. [Vancouver, BC?]: University of British Columbia , 1999.
Website
http://hdl.handle.net/2429/9760
Material Type
Thesis
Call Number
Thesis Shelf
Ovarian cancer is the most lethal gynecological cancer in the Western world, but comparatively little is known about its development. Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e. the mesothelium covering the ovary, but experimental evidence fo…
Website
http://hdl.handle.net/2429/9760
Author
Ong, Aldrich Dixon
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1999
Subject
Faculty of Medicine
Theses
Abstract
Ovarian cancer is the most lethal gynecological cancer in the Western world, but comparatively little is known about its development. Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e. the mesothelium covering the ovary, but experimental evidence for this origin has been lacking. Contrary to most epithelia where neoplastic progression is associated with loss of E-cadherin, this cell-cell adhesion molecule is sparse in normal human OSE but its expression increases in ovarian epithelial metaplasia and neoplasia.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Prostaglandin F[sub 2a]-mediated luteolytic and luteotrophic effects on the human granulosa-luteal cell

https://cwslc.andornot.com/en/permalink/catalog113976
Vaananen, Jeffrey Eric. [Vancouver, BC?]: University of British Columbia , 1997.
Website
http://hdl.handle.net/2429/6811
Material Type
Thesis
Call Number
Thesis Shelf
These studies examined the effects of prostaglandin-F[sub 2a] (PGF[sub 2a]) on progesterone and 178-estradiol (estradiol) production, as well as DNA and PGF[sub 2a]-receptor (PGF[sub 2a]-R) mRNA levels, in the human granulosa-luteal cell (GLC). Additionally, the interactions of PGF[sub 2a] with hum…
Website
http://hdl.handle.net/2429/6811
Author
Vaananen, Jeffrey Eric
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1997
Subject
Faculty of Medicine
Theses
Abstract
These studies examined the effects of prostaglandin-F[sub 2a] (PGF[sub 2a]) on progesterone and 178-estradiol (estradiol) production, as well as DNA and PGF[sub 2a]-receptor (PGF[sub 2a]-R) mRNA levels, in the human granulosa-luteal cell (GLC). Additionally, the interactions of PGF[sub 2a] with human chorionic gonadotrophin (hCG), gonadotrophin-releasing hormone (GnRH) and prostaglandin E₂ (PGE₂) were examined, with respect to progesterone and estradiol production.
Language
English
Material Type
Thesis
Call Number
Thesis Shelf
Websites
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Regulation of rat ovarian gonadotropin Releasing hormone receptor mRNA levels

https://cwslc.andornot.com/en/permalink/catalog113977
Vaananen, Celine Claire. [Vancouver, BC?]: University of British Columbia , 1997.
Website
http://hdl.handle.net/2429/6615
Material Type
Thesis
Call Number
Thesis Shelf
The studies undertaken herewithin sought to characterize the pattern of regulation of the gonadotrophin-releasing hormone receptor (GnRH-R) mRNA levels in the rat ovary. The demonstration of gonadotrophin-releasing hormone (GnRH) transcripts in steroidproducing and steroid-dependent tissues suggest…
Website
http://hdl.handle.net/2429/6615
Author
Vaananen, Celine Claire
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1997
Subject
Faculty of Medicine
Theses
Abstract
The studies undertaken herewithin sought to characterize the pattern of regulation of the gonadotrophin-releasing hormone receptor (GnRH-R) mRNA levels in the rat ovary. The demonstration of gonadotrophin-releasing hormone (GnRH) transcripts in steroidproducing and steroid-dependent tissues suggests that GnRH may be implicated in the modulation of steroid action in those target tissues. Expression of GnRH-R mRNA increases in gonadal tissues and the pituitary with age, supporting the concept of GnRH as a local regulator in the developing rat as well as in the adult.
Language
English
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Localization and regulation of mRNA transcripts encoding activin receptors in human placental trophoblast cells

https://cwslc.andornot.com/en/permalink/catalog113978
Chen, Victor. [Vancouver, BC?]: University of British Columbia , 1997.
Website
http://hdl.handle.net/2429/6315
Material Type
Thesis
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Thesis Shelf
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type…
Website
http://hdl.handle.net/2429/6315
Author
Chen, Victor
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1997
Subject
Faculty of Medicine
Theses
Abstract
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type II (II and ILB) receptors. The role of activin in the human placenta is not clearly understood. In this study, the detection of inlubin/activin subunit and ActRI mRNA were examined in first trimester cytotrophoblasts, term cytotrophoblasts, extravillous trophoblast (EVT) cells, immortalized extravillous trophoblast (LEVT) cells, JEG-3 cells, decidual tissue, and decidual cells.
Language
English
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Single cell studies of calcium as second messenger in human granulosa-lutein and embryonic kidney 293 cells

https://cwslc.andornot.com/en/permalink/catalog113979
Lee, Pearly S.N. [Vancouver, BC?]: University of British Columbia , 1999.
Website
http://hdl.handle.net/2429/10789
Material Type
Thesis
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Thesis Shelf
It is well established that LH action is mediated primarily by adenylate cyclase/cAMP. Conversely, the role of inositol phosphate/calcium in LH signalling has only recently been investigated. We examined the effects of gonadotrophins on intracellular calcium mobilisation in HEK293 cells transiently…
Website
http://hdl.handle.net/2429/10789
Author
Lee, Pearly S.N.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1999
Subject
Faculty of Medicine
Theses
Abstract
It is well established that LH action is mediated primarily by adenylate cyclase/cAMP. Conversely, the role of inositol phosphate/calcium in LH signalling has only recently been investigated. We examined the effects of gonadotrophins on intracellular calcium mobilisation in HEK293 cells transiently transfected with human wild type or chimeric gonadotrophs receptors (n=3400). Intracellular free calcium concentration was measured using fura-2 microspectrofluorimetric techniques. Human LH (2-4 μg/ml) arid CG (10 IU/ml) consistently evoked oscillatory calcium signals in HEK293 cells transfected with hLHr, whereas hFSH (2-4 μg/ml) failed to elicit any calcium responses.
Language
English
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The role for insulin-like growth factor-I in preimplantation embryonic development and decidualization following superovulation in the rat

https://cwslc.andornot.com/en/permalink/catalog113980
Katagiri, Seiji. [Vancouver, BC?]: University of British Columbia , 1996.
Website
http://hdl.handle.net/2429/4814
Material Type
Thesis
Call Number
Thesis Shelf
Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation…
Website
http://hdl.handle.net/2429/4814
Author
Katagiri, Seiji
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1996
Subject
Faculty of Medicine
Theses
Abstract
Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation in the rat. IGF-I may be beneficial to preimplantation embryonic development. IGF-I stimulated embryonic development and metabolism in vitro and increased the rate of implantation and fetal development when the blastocysts were transferred into a receptive uterus.
Language
English
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Maternal progesterone and fetal cortisol responses to hypoxemia in pregnant sheep

https://cwslc.andornot.com/en/permalink/catalog113981
Wu, Li-Hua. [Vancouver, BC?]: University of British Columbia , 1996.
Website
http://hdl.handle.net/2429/4269
Material Type
Thesis
Call Number
Thesis Shelf
The placenta is an important endocrine organ producing large amounts of steroid and protein hormones which are released into the maternal and fetal circulations. Moreover, it has a very high metabolic rate and consumes a significant proportion of the oxygen and glucose delivered to the uterus and i…
Website
http://hdl.handle.net/2429/4269
Author
Wu, Li-Hua
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1996
Subject
Faculty of Medicine
Theses
Abstract
The placenta is an important endocrine organ producing large amounts of steroid and protein hormones which are released into the maternal and fetal circulations. Moreover, it has a very high metabolic rate and consumes a significant proportion of the oxygen and glucose delivered to the uterus and its contents. However, while there have been many studies on the effects of hypoxemia on fetal cardiovascular, metabolic and endocrine functions, there are limited data on the effects of reduced oxygenation on placental endocrine activities. In the present study, we examined the effects of acute (2-h) moderate (maternal Pao₂ lowered by 27-35%, n=5) and severe (maternal Pao₂ lowered by 41-58%, n=4) hypoxemia on placental progesterone output into the maternal circulation in 7 chronically instrumented pregnant sheep (125 to 136 d). Hypoxemia was achieved by lowering maternal inspired O₂ concentration and the hypoxemia period was preceded and followed by 2 h pre-hypoxia and recovery periods, respectively. Control experiments (n=4), involving 6 h periods of normoxia were also carried out.
Language
English
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Characterization of the human gonadotropin-releasing hormone receptor gene at the molecular level

https://cwslc.andornot.com/en/permalink/catalog113982
Fan, Nancy C. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7255
Material Type
Thesis
Call Number
Thesis Shelf
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling sti…
Website
http://hdl.handle.net/2429/7255
Author
Fan, Nancy C.
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling stimulates the synthesis and release of both luteinizing hormone and follicle stimulating hormone from the anterior pituitary. In addition, GnRH - GnRH receptor binding acts locally to regulate human chorionic gonadotropin secretion in the placenta and steroidogenesis in the ovary. The objective of this thesis was to isolate and characterize the gene for the GnRH receptor in human.
Language
English
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Superovulation and chromosomal aberrations

https://cwslc.andornot.com/en/permalink/catalog113983
Ma, Sai. [Vancouver, BC?]: University of British Columbia , 1995.
Website
http://hdl.handle.net/2429/7516
Material Type
Thesis
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In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fai…
Website
http://hdl.handle.net/2429/7516
Author
Ma, Sai
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1995
Subject
Faculty of Medicine
Theses
Abstract
In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fail to achieve or sustain implantation. The failure of implantation has raised questions about the possible detrimental effect of superovulation on chromosomal complements. In this study, the hypothesis that chromosomal aberrations exist in mouse preimplantation embryos and human unfertilized oocytes after superovulation, was tested. The incidence of aneuploidy in spontaneously ovulated group (5.6%) was similar to that reported by others.
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English
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Regulation of cytochrome P450 and P450 mRNA in human granulosa-luteal cells

https://cwslc.andornot.com/en/permalink/catalog113984
Ge, Hong. [Vancouver, BC?]: University of British Columbia , 1994.
Website
http://hdl.handle.net/2429/3482
Material Type
Thesis
Call Number
Thesis Shelf
This thesis investigated the expression and regulation of cytochrome P450s, aromatase (P450arom) and cholesterol side chain cleavage (P450scc) enzyme mRNAs in human granulosa-luteal cells using reverse transcription-polymerase chain reaction (RT-PCR). The two enzymes are instrumental in steroid hor…
Website
http://hdl.handle.net/2429/3482
Author
Ge, Hong
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1994
Subject
Faculty of Medicine
Theses
Abstract
This thesis investigated the expression and regulation of cytochrome P450s, aromatase (P450arom) and cholesterol side chain cleavage (P450scc) enzyme mRNAs in human granulosa-luteal cells using reverse transcription-polymerase chain reaction (RT-PCR). The two enzymes are instrumental in steroid hormone biosynthesis.
Language
English
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Study of serum inhibin levels in two in-vitro fertilization protocols

https://cwslc.andornot.com/en/permalink/catalog113985
Kwong, Eugene Cheuk Kun. [Vancouver, BC?]: University of British Columbia , 1994.
Website
http://hdl.handle.net/2429/5375
Material Type
Thesis
Call Number
Thesis Shelf
In order to characterize and compare the pattern of inhibin production in the follicular phase between patients of the clomiphene citrate/human menopausal gonadotropin (hMG) and Buserelin/hMG protocols in in-vitro fertilization, serum inhibin levels from 20 patients in each protocol were measured. …
Website
http://hdl.handle.net/2429/5375
Author
Kwong, Eugene Cheuk Kun
Place of Publication
[Vancouver, BC?]
Publisher
University of British Columbia
Publication Date
1994
Subject
Faculty of Medicine
Theses
Abstract
In order to characterize and compare the pattern of inhibin production in the follicular phase between patients of the clomiphene citrate/human menopausal gonadotropin (hMG) and Buserelin/hMG protocols in in-vitro fertilization, serum inhibin levels from 20 patients in each protocol were measured. The patients were matched for age and had tubal diseases only. It was hypothesized that the serum inhibin levels would be different in these two groups due to possible local actions of clomiphene citrate and Buserelin (a GnRH agonist) on the ovary.
Language
English
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