Browse and borrow resources that support the learning needs and professional development of C&W staff, clinicians, students and faculty.
Confidently Perform Accurate, Efficient, and Effective Physical Examinations.; Master the techniques for successful physical examinations with the #1 choice for complete, authoritative guidance. This highly regarded text in book-only format includes fully-illustrated, step-by-step techniques that o…
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CURRENT Medical Diagnosis & Treatment is the most comprehensive, reliable, and timely reference available to answer common questions that arise in everyday clinical practice. Written by clinicians renowned in their respective fields, this trusted classic offers expert advice on all aspects of outpa…
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A point-of-care guide for internal medicine trainees; When students and residents begin a new rotation in internal medicine, they often start from scratch, relying on their own research to prepare for consultations. What questions are crucial during history taking? What should the physical examinat…
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Launched by healthcare providers in January 2018, the #aHand2Hold campaign confronted the Quebec government's practice of separating children from their families during medical evacuation airlifts, which disproportionately affected remote and northern Indigenous communities. Pediatric emergency phy…
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The Basic Life Support (BLS) for Healthcare Providers (HCP) is a classroom course that is designed to teach a variety of healthcare professionals how to recognize a number of life-threatening emergencies, how to provide CPR, how to use an AED and how to relieve choking in a safe, timely and effecti…
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The Neonatal Resuscitation Program (NRP) is an educational program jointly sponsored with the American Heart Association (AHA). The course conveys an evidence-based approach to care of the newborn at birth and facilitates effective team-based care for healthcare professionals who care for newborns …
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Extensively revised toincorporate recent research and current clinical practice ,The Developing Human: Clinically Oriented Embryology, 11th Edition,covers all aspects of normal and abnormal embryonic and fetal development. In a clear, concise manner and lavishly illustrated throughout, this textboo…
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The Pediatric Advanced Life Support (PALS) Provider Course is designed for healthcare providers who initiate and direct basic through advanced life support. Course concepts are designed to be used throughout the stabilization and transport phases for both in-hospital and out-of-hospital pediatric e…
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Advanced Cardiovascular Life Support (ACLS) courses provide critical training to Canadian healthcare professionals. The Heart & Stroke ACLS course has been updated to reflect new science from the 2020 Guidelines Update for CPR and Emergency Cardiovascular Care (2020 Guidelines for CPR and ECC).; AC…
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Ovarian cancer is the most lethal gynecological cancer in the Western world, but comparatively little is known about its development. Epithelial ovarian carcinomas are thought to originate in the ovarian surface epithelium (OSE), i.e. the mesothelium covering the ovary, but experimental evidence fo…
These studies examined the effects of prostaglandin-F[sub 2a] (PGF[sub 2a]) on progesterone and 178-estradiol (estradiol) production, as well as DNA and PGF[sub 2a]-receptor (PGF[sub 2a]-R) mRNA levels, in the human granulosa-luteal cell (GLC). Additionally, the interactions of PGF[sub 2a] with hum…
The studies undertaken herewithin sought to characterize the pattern of regulation of the gonadotrophin-releasing hormone receptor (GnRH-R) mRNA levels in the rat ovary. The demonstration of gonadotrophin-releasing hormone (GnRH) transcripts in steroidproducing and steroid-dependent tissues suggest…
There is increasing evidence to suggest that activin can function as an autocrine/paracrine regulator in various tissues, including the reproductive system. At the cellular level, activin acts via a family of activin receptor (ActR) subtypes which includes two type I (ActRI and ActRLB) and two type…
It is well established that LH action is mediated primarily by adenylate cyclase/cAMP. Conversely, the role of inositol phosphate/calcium in LH signalling has only recently been investigated. We examined the effects of gonadotrophins on intracellular calcium mobilisation in HEK293 cells transiently…
Superovulation causes detrimental effects, including embryonic loss and implantation failure. This study determined potential roles for insulin-like growth factor (IGF-I) in uterine environment regulation and preimplantation development, in conjunction with the detrimental effects of superovulation…
The placenta is an important endocrine organ producing large amounts of steroid and protein hormones which are released into the maternal and fetal circulations. Moreover, it has a very high metabolic rate and consumes a significant proportion of the oxygen and glucose delivered to the uterus and i…
The gonadotropin - releasing hormone (GnRH) receptor is a plasma membrane associated receptor and a member of the GTP - binding protein coupled receptor family. The interaction of the ligand, GnRH, and the GnRH receptor is a critical event in the endocrine control of reproduction. This coupling sti…
In vitro fertilization (IVF) has been achieved in several mammalian species, including humans. Using the technique of IVF and embryo transfer, pregnancies can now be established in infertile women and thousands of live births have occurred. However, many of the embryos transferred to the uterus fai…
This thesis investigated the expression and regulation of cytochrome P450s, aromatase (P450arom) and cholesterol side chain cleavage (P450scc) enzyme mRNAs in human granulosa-luteal cells using reverse transcription-polymerase chain reaction (RT-PCR). The two enzymes are instrumental in steroid hor…
In order to characterize and compare the pattern of inhibin production in the follicular phase between patients of the clomiphene citrate/human menopausal gonadotropin (hMG) and Buserelin/hMG protocols in in-vitro fertilization, serum inhibin levels from 20 patients in each protocol were measured. …